DE69629333D1 - Adduktabschirmungstest - Google Patents
AdduktabschirmungstestInfo
- Publication number
- DE69629333D1 DE69629333D1 DE69629333T DE69629333T DE69629333D1 DE 69629333 D1 DE69629333 D1 DE 69629333D1 DE 69629333 T DE69629333 T DE 69629333T DE 69629333 T DE69629333 T DE 69629333T DE 69629333 D1 DE69629333 D1 DE 69629333D1
- Authority
- DE
- Germany
- Prior art keywords
- signal
- label
- binding partner
- alteration
- ability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US478221 | 1995-06-07 | ||
| US08/478,221 US5731148A (en) | 1995-06-07 | 1995-06-07 | Adduct protection assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69629333D1 true DE69629333D1 (de) | 2003-09-11 |
| DE69629333T2 DE69629333T2 (de) | 2004-06-24 |
Family
ID=23899023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69629333T Expired - Lifetime DE69629333T2 (de) | 1995-06-07 | 1996-06-03 | Adduktabschirmungstest |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5731148A (de) |
| EP (1) | EP0747706B1 (de) |
| JP (1) | JP3577085B2 (de) |
| KR (1) | KR19990022460A (de) |
| AT (1) | ATE246807T1 (de) |
| AU (1) | AU703605B2 (de) |
| CA (1) | CA2222556C (de) |
| DE (1) | DE69629333T2 (de) |
| DK (1) | DK0747706T3 (de) |
| ES (1) | ES2203656T3 (de) |
| WO (1) | WO1996041197A1 (de) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5714380A (en) | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
| US7070925B1 (en) | 1996-07-16 | 2006-07-04 | Gen-Probe Incorporated | Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe |
| JP2000514307A (ja) * | 1996-07-16 | 2000-10-31 | ジェン―プローブ・インコーポレーテッド | 増加した標的特異的ｔ▲下ｍ▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 |
| ES2324503T3 (es) | 1997-04-10 | 2009-08-07 | Stichting Katholieke Universiteit University Medical Centre Nijmegen | Pca3, genes pca3 y metodos de uso. |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| EP0975807B1 (de) | 1997-05-02 | 2006-09-27 | Gen-Probe Incorporated | Zwei-schritt hybridisierung und einfang von einem polynukleotid |
| US6180340B1 (en) | 1997-10-31 | 2001-01-30 | Gen-Probe Incorporated | Extended dynamic range assays |
| WO1999049293A2 (en) * | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
| CA2333253C (en) | 1998-07-02 | 2010-09-07 | Gen-Probe Incorporated | Molecular torches |
| US5998175A (en) * | 1998-07-24 | 1999-12-07 | Lumigen, Inc. | Methods of synthesizing and amplifying polynucleotides by ligation of multiple oligomers |
| US6245519B1 (en) | 1999-02-12 | 2001-06-12 | Gen-Probe Incorporated | Protection probes |
| EP1422298B1 (de) | 1999-07-09 | 2010-01-27 | Gen-Probe Incorporated | HIV-1 Detektion mittels Nukleinsäureamplifizierung |
| US6506887B1 (en) * | 1999-07-29 | 2003-01-14 | Somalogic, Incorporated | Conditional-selex |
| AU7636400A (en) | 1999-09-29 | 2001-04-30 | Diagnocure Inc. | Pca3 messenger rna species in benign and malignant prostate tissues |
| US6506567B2 (en) * | 2000-01-31 | 2003-01-14 | Fuji Photo Film Co., Ltd. | Water-soluble flourescent intercalator compound |
| AU784335B2 (en) * | 2000-02-03 | 2006-03-16 | Research Development Foundation | Signaling aptamers that transduce molecular recognition to differential signal |
| WO2002048404A2 (en) * | 2000-12-14 | 2002-06-20 | Gen-Probe Incorporated | Method and kit for enhancing the association rates of polynucleotides |
| EP1423522A2 (de) | 2001-01-23 | 2004-06-02 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus-replikons und replikon- verbesserte zellen |
| US6780602B2 (en) * | 2001-11-01 | 2004-08-24 | Microbiosystems, Limited Partnership | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
| ATE519861T1 (de) | 2002-06-14 | 2011-08-15 | Gen Probe Inc | Zusammensetzungen zum nachweis von hepatitis-b- virus |
| CA2501946C (en) | 2002-10-16 | 2014-12-23 | Gen-Probe Incorporated | Compositions and methods for detecting west nile virus |
| CA2513780C (en) | 2003-02-07 | 2014-12-30 | Diagnocure Inc. | Method to detect prostate cancer from a urine sample |
| US20060257929A1 (en) * | 2003-11-12 | 2006-11-16 | Microbiosystems, Limited Partnership | Method for the rapid taxonomic identification of pathogenic microorganisms and their toxic proteins |
| AU2004303886B2 (en) | 2003-12-19 | 2009-09-03 | Gen-Probe Incorporated | Compositions, methods and kits for detecting the nucleic acids of HIV-1 and HIV-2 |
| CN104109712A (zh) | 2004-02-18 | 2014-10-22 | 克罗莫塞尔公司 | 使用信号探针的方法和材料 |
| CA2562517A1 (en) | 2004-04-16 | 2005-10-27 | Spartan Bioscience Inc. | System for rapid nucleic acid amplification and detection |
| ATE466107T1 (de) | 2004-07-01 | 2010-05-15 | Gen Probe Inc | Verfahren und zusammensetzungen zum nachweis von nukleinsäuren in einer biologischen probe |
| CA2838428C (en) * | 2004-07-13 | 2015-09-29 | Gen-Probe Incorporated | Compositions and methods for detection of hepatitis a virus nucleic acid |
| EP1794328B1 (de) | 2004-09-30 | 2015-05-27 | Gen-Probe Incorporated | Verfahren zum nachweis und zur quantifizierung von hiv-1 |
| CA2582661C (en) | 2004-11-09 | 2015-08-11 | Gen-Probe Incorporated | Compositions and methods for detecting group a streptococci |
| CA2491067A1 (en) | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
| EP2471805A3 (de) | 2005-05-06 | 2013-01-16 | Gen-Probe Incorporated | Zusammensetzungen und Verfahren zur spezifischen Detektion von Nukleinsäuren der Viren Influenza A oder B |
| JP5187847B2 (ja) | 2005-05-06 | 2013-04-24 | ジェン−プローブ・インコーポレーテッド | 核酸標的の捕獲方法 |
| JP2010511385A (ja) * | 2006-11-30 | 2010-04-15 | クロモセル コーポレイション | タンパク質産生のための至適化された宿主細胞 |
| EP1978111B1 (de) | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa |
| US9458451B2 (en) | 2007-06-21 | 2016-10-04 | Gen-Probe Incorporated | Multi-channel optical measurement instrument |
| JP5646455B2 (ja) | 2008-04-21 | 2014-12-24 | ジェン−プロウブ インコーポレイテッド | チクングニヤウイルスを検出するための方法 |
| EP2806037B1 (de) | 2008-05-13 | 2016-09-21 | Gen-Probe Incorporated | Inaktivierbare Target-Capture-Oligomere zur Verwendung bei der selektiven Hybridisierung und beim Fangen von Zielnukleinsäuresequenzen |
| CA2723917A1 (en) | 2008-05-30 | 2009-12-30 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of salmonella |
| US8097412B2 (en) * | 2008-07-12 | 2012-01-17 | Biodiagnostics, Inc. | DNA-based test for detection of annual and intermediate ryegrass |
| CA2638458A1 (en) * | 2008-07-31 | 2010-01-31 | Spartan Bioscience Inc. | Thermal recycling by positioning relative to fixed-temperature source |
| WO2010068473A1 (en) | 2008-11-25 | 2010-06-17 | Gen-Probe Incorporated | Compositions and methods for detecting small rnas, and uses thereof |
| CA2746539A1 (en) | 2008-12-30 | 2010-07-08 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
| US8368882B2 (en) | 2009-01-30 | 2013-02-05 | Gen-Probe Incorporated | Systems and methods for detecting a signal and applying thermal energy to a signal transmission element |
| EP3705486B1 (de) | 2009-02-26 | 2022-11-16 | Gen-Probe Incorporated | Assay zum nachweisen menschlicher parvoviren-nukleinsäure |
| EP2588629B1 (de) | 2010-06-30 | 2017-05-17 | Gen-Probe Incorporated | Methode und apparatur zur identifizierung von analyt-beinhaltenden proben unter verwendung von single-read determination des analyten und prozesskontrollsignalen |
| EP2593569B1 (de) | 2010-07-12 | 2018-01-03 | Gen-Probe Incorporated | Zusammensetzungen und tests für den nachweis von nukleinsäuren des saisonalen h1 influenza a virus |
| US9938590B2 (en) | 2010-09-16 | 2018-04-10 | Gen-Probe Incorporated | Capture probes immobilizable via L-nucleotide tail |
| EP2625297B1 (de) | 2010-10-04 | 2018-10-10 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, verfahren und kits für den nachweis von adenovirus-nukleinsäuren |
| ES2945966T3 (es) | 2011-07-15 | 2023-07-11 | Gen Probe Inc | Composiciones y procedimiento para detectar ácido nucleico del parvovirus humano y ácido nucleico del virus de la hepatitis A |
| DE102011120550B4 (de) | 2011-12-05 | 2013-11-07 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren |
| EP2971131A4 (de) | 2013-03-15 | 2016-11-23 | Chromocell Corp | Verfahren und materialien unter verwendung von signalsonden |
| JP6767374B2 (ja) | 2014-10-20 | 2020-10-14 | ジェン−プローブ・インコーポレーテッド | 赤血球溶解溶液 |
| EP3387107B1 (de) | 2015-12-11 | 2020-08-12 | Spartan Bioscience Inc. | Röhrchenverschlusssystem und verfahren zur nukleinsäureamplifikation |
| DE202017007129U1 (de) | 2016-04-27 | 2019-08-29 | Gen-Probe Incorporated | Lysereagenz für Blutzellen |
| EP4212635A1 (de) | 2017-03-24 | 2023-07-19 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von rsv a in proben |
| EP3601617B3 (de) | 2017-03-24 | 2024-03-20 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis oder zur quantifizierung des parainfluenzavirus |
| JP6956800B2 (ja) | 2017-03-25 | 2021-11-02 | ジェン−プローブ・インコーポレーテッド | アデノウイルス、メタニューモウイルス、および／またはライノウイルス核酸を検出するための組成物、方法、およびキット |
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| EP3830302B1 (de) | 2018-08-01 | 2022-10-05 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von nukleinsäuren des epstein-barr-virus |
| WO2020033557A1 (en) | 2018-08-08 | 2020-02-13 | Gen-Probe Incorporated | Compositions, methods and kits for detecting mycoplasma genitalium |
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| WO2020086546A1 (en) | 2018-10-22 | 2020-04-30 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus |
| EP3942078A1 (de) | 2019-03-22 | 2022-01-26 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zur detektion von gruppe-a-streptococcus |
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| AU2020343334A1 (en) | 2019-09-05 | 2022-04-07 | Gen-Probe Incorporated | Detection of Chlamydia trachomatis nucleic acid variants |
| JP2023516683A (ja) | 2020-03-04 | 2023-04-20 | ジェン－プローブ・インコーポレーテッド | ＳＡＲＳ－ＣｏＶ－２核酸を検出するための組成物および方法 |
| CN116323440A (zh) | 2020-10-21 | 2023-06-23 | 简·探针公司 | 流体容器管理系统 |
| AU2022319876A1 (en) | 2021-07-27 | 2024-01-18 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal pathogens |
| WO2023175434A1 (en) | 2022-03-15 | 2023-09-21 | Diagenode S.A. | Detection of methylation status of a dna sample |
| WO2024054924A1 (en) | 2022-09-08 | 2024-03-14 | Gen-Probe Incorporated | Method of detecting nucleic acid analytes using dual-specificity primers |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6515469A (de) * | 1965-01-22 | 1966-07-25 | ||
| US4190496A (en) * | 1971-05-14 | 1980-02-26 | Syva Company | Homogeneous enzyme assay for antibodies |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US4199559A (en) * | 1974-08-12 | 1980-04-22 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4383031A (en) * | 1975-04-28 | 1983-05-10 | Miles Laboratories, Inc. | Homogeneous chemiluminescent specific binding assay |
| US4174384A (en) * | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US4318707A (en) * | 1978-11-24 | 1982-03-09 | Syva Company | Macromolecular fluorescent quencher particle in specific receptor assays |
| CA1185177A (en) * | 1981-07-17 | 1985-04-09 | Larry E. Morrison | Non-radiative energy transfer immunochemical technique |
| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| US4668640A (en) * | 1981-12-11 | 1987-05-26 | Abbott Laboratories | Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins |
| GB2112779B (en) * | 1981-12-11 | 1986-10-15 | Welsh Nat School Med | Aryl acridinium esters as luminescent labelling materials |
| US4462931A (en) * | 1982-06-16 | 1984-07-31 | American Cyanamid Company | Enhanced aqueous chemiluminescent systems |
| US4508642A (en) * | 1983-04-21 | 1985-04-02 | World Victor B | Method of obtaining greater lifetime duration from chemiluminescent systems |
| US4640898A (en) * | 1983-08-01 | 1987-02-03 | University Of Health Sciences/The Chicago Medical School | Homogeneous fluorescence ligang binding assay based upon preferential alteration of the respective intensities of bound and free label by solvent components |
| US4816419A (en) * | 1983-08-01 | 1989-03-28 | University Of Health Sciences/The Chicago Medical School | Fluorescence ligand binding assay using charge-matched dye and solvent components |
| US4582789A (en) * | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
| AU580042B2 (en) * | 1984-03-22 | 1988-12-22 | Bresatec Limited | Non-radioactive biological probes |
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US4670379A (en) * | 1984-12-19 | 1987-06-02 | E. I. Du Pont De Nemours And Company | Polynucleotide hydridization assays employing catalyzed luminescence |
| EP0187332B1 (de) * | 1985-01-10 | 1989-02-01 | Molecular Diagnostics, Inc. | Photochemisches Verfahren zum Markieren von Nucleinsäuren zum Nachweis in Hybridisationsproben |
| US4655969A (en) * | 1985-04-03 | 1987-04-07 | Richter Herbert P | Chemiluminescent systems |
| JP2509574B2 (ja) * | 1985-08-15 | 1996-06-19 | アモコ・コーポレーション | 標識付けした核酸 |
| JPS6261969A (ja) * | 1985-09-06 | 1987-03-18 | アモコ・コーポレーション | アクリジニウムエステルの合成法 |
| DE3545398A1 (de) * | 1985-12-20 | 1987-06-25 | Boehringer Mannheim Gmbh | Verfahren zur steigerung der quanten-ausbeute bei der oxidation von luminol durch peroxide in gegenwart von peroxidase |
| US4698183A (en) * | 1986-02-04 | 1987-10-06 | American Cyanamid Company | High light output-short duration chemiluminescent compositions |
| DE3645292C2 (de) * | 1986-08-22 | 1997-12-11 | Hoechst Ag | Chemilumineszenzimmunoassays und ein Verfahren zu ihrer Herstellung |
| US4745181A (en) * | 1986-10-06 | 1988-05-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| US4918192A (en) * | 1986-10-06 | 1990-04-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| US5110932A (en) * | 1986-10-06 | 1992-05-05 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| DE3750503T2 (de) * | 1986-10-22 | 1995-02-09 | Abbott Lab | Chemilumineszierende Acridinium- und Phenantridiniumsalze. |
| JPS63107898A (ja) * | 1986-10-23 | 1988-05-12 | Natl Inst For Res In Inorg Mater | プラズマを用いるダイヤモンドの合成法 |
| US4927769A (en) * | 1987-07-08 | 1990-05-22 | Ciba Corning Diagnostics Corp. | Method for enhancement of chemiluminescence |
| JP3787352B2 (ja) * | 1987-09-21 | 2006-06-21 | ジェン−プローブ・インコーポレイテッド | ハイブリダイゼーション保護検定 |
| PT88550A (pt) * | 1987-09-21 | 1989-07-31 | Ml Tecnology Ventures Lp | Processo para a preparacao de reagentes de ligacao nao nucleotidicos para sondas nucleotidicas |
| US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| US5185439A (en) * | 1987-10-05 | 1993-02-09 | Gen-Probe Incorporated | Acridinium ester labelling and purification of nucleotide probes |
| US4883898A (en) * | 1987-12-10 | 1989-11-28 | University Of Chicago | Chemiluminescent compounds |
| NL8703075A (nl) * | 1987-12-18 | 1989-07-17 | Nederlanden Staat | Acridiniumverbindingen als chemiluminescentie-merkstof. |
| US5338847A (en) * | 1987-12-31 | 1994-08-16 | London Diagnostics, Inc. | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation |
| NZ227506A (en) * | 1987-12-31 | 1992-06-25 | London Diagnostics Inc | Specific binding assays using chemiluminescent compounds |
| US5321136A (en) * | 1987-12-31 | 1994-06-14 | London Diagnostics, Inc. | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom |
| US5284951A (en) * | 1987-12-31 | 1994-02-08 | London Diagnostics, Inc. | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom |
| DE3844954C2 (de) * | 1988-02-20 | 1998-07-16 | Hoechst Ag | Spezielle chemilumineszierende Acridinderivate und ihre Verwendung in Lumineszenzimmunoassays |
| US4950613A (en) * | 1988-02-26 | 1990-08-21 | Gen-Probe Incorporated | Proteted chemiluminescent labels |
| AU634716B2 (en) * | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5241070A (en) * | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
| CA1339491C (en) * | 1988-09-26 | 1997-10-07 | Say-Jong Law | Nucleophilic polysubstituted aryl acridinium ester and uses thereof |
| US5093270A (en) * | 1989-05-24 | 1992-03-03 | Ciba Corning Diagnostics Corp. | Method for enhancing signal release from liposomes using water-miscible alcohols |
| GB2233451B (en) * | 1989-06-27 | 1993-09-15 | Tropix Inc | Chemiluminescence enhancement |
| JPH0335147A (ja) * | 1989-07-03 | 1991-02-15 | Doujin Kagaku Kenkyusho:Kk | 化学発光の検出 |
| ES2124231T3 (es) * | 1990-10-26 | 1999-02-01 | Genta Inc | Procedimiento mejorado para sintesis de oligomeros. |
| EP0511366A1 (de) * | 1990-11-21 | 1992-11-04 | Beckman Instruments, Inc. | Chemilumineszierende derivate |
| EP0492570B1 (de) * | 1990-12-24 | 2001-05-02 | Enzo Diagnostics, Inc. | Verfahren zum Nachweis eines Zielpolynukleotids in einer Probe unter Verwendung eines Reagenz, das den Hintergrund verringert, und eine dieses Reagenz enthaltende Zusammensetzung und Kit |
| JPH0579985A (ja) * | 1991-09-24 | 1993-03-30 | Kyoto Daiichi Kagaku:Kk | 化学発光増強剤及び増強方法 |
| JPH05255264A (ja) * | 1992-03-13 | 1993-10-05 | Sanyo Chem Ind Ltd | 標識剤および標識されたリガンドの製法 |
| JPH07506254A (ja) * | 1992-05-06 | 1995-07-13 | ジェン−プローブ・インコーポレイテッド | ヒトｂ型肝炎ウイルスに対する核酸増幅オリゴヌクレオチドおよびプローブ |
| JP3248628B2 (ja) * | 1992-06-25 | 2002-01-21 | 国際試薬株式会社 | 化学発光性化合物およびこれを用いるアッセイ法 |
| WO1994002486A1 (en) * | 1992-07-20 | 1994-02-03 | Syntex (U.S.A.) Inc. | Novel chemiluminescent compounds and methods of use |
| JP3207933B2 (ja) * | 1992-09-09 | 2001-09-10 | 株式会社ヤトロン | アクリジニウム誘導体の発光方法及びそれを用いた検査対象物質の検出方法 |
| EP0602524A1 (de) * | 1992-12-15 | 1994-06-22 | Hoechst Aktiengesellschaft | Chemilumineszenzmarkierte Gensonden und ihre Verwendung in Gensondentesten |
| JP3584379B2 (ja) * | 1993-02-04 | 2004-11-04 | 持田製薬株式会社 | アクリジニウム化合物およびアクリジニウム化合物複合体 |
| KR100325554B1 (ko) * | 1993-03-26 | 2002-11-02 | 젠-프로브 인코포레이티드 | 사람의면역결핍 바이러스타입1의검출 |
| US5491072A (en) * | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| WO1995003427A2 (en) * | 1993-07-19 | 1995-02-02 | Gen-Probe Incorporated | Oligonucleotide screening assay |
| JPH07330838A (ja) * | 1994-06-10 | 1995-12-19 | Nippon Oil & Fats Co Ltd | アクリダン基含有高分子および化学発光方法 |
| JP3694044B2 (ja) * | 1994-06-22 | 2005-09-14 | 株式会社三菱化学ヤトロン | アクリジニウム誘導体の発光方法及びその方法を用いた検査対象物質の検出方法 |
| EP0709466B1 (de) * | 1994-10-28 | 2006-09-27 | Gen-Probe Incorporated | Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen |
-
1995
- 1995-06-07 US US08/478,221 patent/US5731148A/en not_active Expired - Lifetime
-
1996
- 1996-05-23 JP JP50074597A patent/JP3577085B2/ja not_active Expired - Lifetime
- 1996-05-23 KR KR1019970708941A patent/KR19990022460A/ko not_active Application Discontinuation
- 1996-05-23 CA CA002222556A patent/CA2222556C/en not_active Expired - Fee Related
- 1996-05-23 WO PCT/US1996/007776 patent/WO1996041197A1/en not_active Application Discontinuation
- 1996-05-23 AU AU60244/96A patent/AU703605B2/en not_active Ceased
- 1996-06-03 AT AT96108880T patent/ATE246807T1/de not_active IP Right Cessation
- 1996-06-03 DK DK96108880T patent/DK0747706T3/da active
- 1996-06-03 EP EP96108880A patent/EP0747706B1/de not_active Expired - Lifetime
- 1996-06-03 DE DE69629333T patent/DE69629333T2/de not_active Expired - Lifetime
- 1996-06-03 ES ES96108880T patent/ES2203656T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK0747706T3 (da) | 2003-11-24 |
| EP0747706A1 (de) | 1996-12-11 |
| WO1996041197A1 (en) | 1996-12-19 |
| JP2002515118A (ja) | 2002-05-21 |
| CA2222556C (en) | 2002-06-11 |
| US5731148A (en) | 1998-03-24 |
| AU703605B2 (en) | 1999-03-25 |
| CA2222556A1 (en) | 1996-12-19 |
| KR19990022460A (ko) | 1999-03-25 |
| DE69629333T2 (de) | 2004-06-24 |
| EP0747706B1 (de) | 2003-08-06 |
| ES2203656T3 (es) | 2004-04-16 |
| AU6024496A (en) | 1996-12-30 |
| JP3577085B2 (ja) | 2004-10-13 |
| ATE246807T1 (de) | 2003-08-15 |
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