ATE240314T1 - Kristalle von benzimidazolderivate und verfahren zu ihrer herstellung - Google Patents

Kristalle von benzimidazolderivate und verfahren zu ihrer herstellung

Info

Publication number
ATE240314T1
ATE240314T1 AT97912445T AT97912445T ATE240314T1 AT E240314 T1 ATE240314 T1 AT E240314T1 AT 97912445 T AT97912445 T AT 97912445T AT 97912445 T AT97912445 T AT 97912445T AT E240314 T1 ATE240314 T1 AT E240314T1
Authority
AT
Austria
Prior art keywords
substituted
optionally
crystals
production
benzimidazole derivatives
Prior art date
Application number
AT97912445T
Other languages
English (en)
Inventor
Masayasu Kato
Toru Ishida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17920069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE240314(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE240314T1 publication Critical patent/ATE240314T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97912445T 1996-11-14 1997-11-13 Kristalle von benzimidazolderivate und verfahren zu ihrer herstellung ATE240314T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30336196 1996-11-14
PCT/JP1997/004136 WO1998021201A1 (en) 1996-11-14 1997-11-13 Crystals of benzimidazole derivatives and their production

Publications (1)

Publication Number Publication Date
ATE240314T1 true ATE240314T1 (de) 2003-05-15

Family

ID=17920069

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97912445T ATE240314T1 (de) 1996-11-14 1997-11-13 Kristalle von benzimidazolderivate und verfahren zu ihrer herstellung

Country Status (18)

Country Link
US (1) US6002011A (de)
EP (1) EP0944617B1 (de)
KR (1) KR100519576B1 (de)
CN (2) CN1171885C (de)
AT (1) ATE240314T1 (de)
AU (1) AU731776B2 (de)
CA (1) CA2269053C (de)
DE (1) DE69722027T2 (de)
DK (1) DK0944617T3 (de)
ES (1) ES2199356T3 (de)
ID (1) ID21547A (de)
IL (1) IL129724A (de)
NZ (1) NZ335145A (de)
PT (1) PT944617E (de)
TR (1) TR199901055T2 (de)
TW (1) TW385306B (de)
WO (1) WO1998021201A1 (de)
ZA (1) ZA9710255B (de)

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PL333847A1 (en) * 1999-06-18 2001-01-02 Inst Farmaceutyczny Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
WO2001002389A1 (en) * 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Crystals of benzimidazole compounds
EP1897877B1 (de) 2000-05-15 2014-09-24 Takeda Pharmaceutical Company Limited Kristallinische Formen von (R)-Lansoprazol
ATE342263T1 (de) 2000-08-04 2006-11-15 Takeda Pharmaceutical Salze von benzimidazol-derivaten und deren verwendung
US7396841B2 (en) 2000-08-18 2008-07-08 Takeda Pharmaceutical Company Limited Injections
CA2436825C (en) 2000-12-01 2011-01-18 Takeda Chemical Industries, Ltd. Process for the crystallization of (r)- or (s)-lansoprazole
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
ES2392960T3 (es) 2001-10-17 2012-12-17 Takeda Pharmaceutical Company Limited Gránulos que contienen gran cantidad de compuesto químico inestable en medio ácido
KR20090045420A (ko) * 2002-02-19 2009-05-07 테바 파마슈티컬 인더스트리즈 리미티드 아토르바스타틴 헤미-칼슘 용매화합물의 탈용매화
CA2480352A1 (en) * 2002-03-27 2003-10-09 Teva Pharmaceutical Industries Ltd. Lansoprazole polymorphs and processes for preparation thereof
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TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
EP1764364A1 (de) * 2002-08-21 2007-03-21 Teva Pharmaceutical Industries Ltd Eine Methode zur Reinigung von Lansoprazol
ATE375338T1 (de) * 2002-08-21 2007-10-15 Teva Pharma Verfahren zur aufreinigung von lanzoprazol
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
CA2771725C (en) 2002-10-16 2015-08-18 Takeda Pharmaceutical Company Limited Solid preparation comprising a non-toxic base and a proton pump inhibitor
ES2237354T3 (es) * 2002-11-18 2007-11-01 Teva Pharmaceutical Industries Ltd. Lansoprazol estable que contiene mas de 500 ppm, hasta aproximadamente 3.000 ppm de agua y mas de 200 ppm, hasta aproximadamente 5.000 ppm de alcohol.
EP1743893A1 (de) 2002-11-18 2007-01-17 Teva Pharmaceutical Industries Ltd. Stabiles Lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm Wasser und mehr als 200 ppm bis zu 5000 ppm Alkohol
JP2006516574A (ja) * 2003-02-05 2006-07-06 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール安定化方法
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
TW200526268A (en) * 2003-12-17 2005-08-16 Takeda Pharmaceutical Injectable composition
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
EP1768668A2 (de) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multi-ppi-dosierform
JP5173191B2 (ja) 2004-09-13 2013-03-27 武田薬品工業株式会社 酸化化合物の製造方法及び製造装置
EP1681056A1 (de) * 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Verfahren zur Herstellung von Lansoprazol
EP1852100B1 (de) 2005-02-25 2018-05-09 Takeda Pharmaceutical Company Limited Verfahren zur herstellung eines beschichteten granulats von benzimidazole
EP1889841A4 (de) * 2005-06-07 2010-04-07 Takeda Pharmaceutical Kristall eines salzes einer benzimidazolverbindung
CA2611917A1 (en) * 2005-06-13 2006-12-21 Takeda Pharmaceutical Company Limited Injection
CN101389316A (zh) 2005-12-28 2009-03-18 武田药品工业株式会社 控制释放固体制剂
KR100758600B1 (ko) * 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
US8129536B2 (en) * 2006-09-22 2012-03-06 Orchid Chemicals & Pharmaceuticals Limited Method for the purification of lansoprazole
WO2008068767A2 (en) * 2006-12-07 2008-06-12 Hetero Drugs Limited A novel crystalline form of lansoprazole
ITMI20062481A1 (it) * 2006-12-22 2008-06-23 Recordati Chem Pharm Processo per la preparazione di lansoprazolo forma i microcristallino
WO2008081891A1 (ja) 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤
US20100286400A1 (en) * 2007-12-31 2010-11-11 Takeda Pharmaceutical Company Limited Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
UA103189C2 (ru) * 2008-03-10 2013-09-25 Такеда Фармасьютикал Компани Лимитед Кристаллическая форма бензимидазольного соединения
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
US20130012714A1 (en) * 2010-02-11 2013-01-10 Orchid Chemicals & Pharmaceuticals Limited Novel solvate of dexlansoprazole
MX2013006247A (es) 2010-12-03 2014-01-31 Takeda Pharmaceutical Tableta oralmente desintegradora.
JP2014501224A (ja) 2010-12-27 2014-01-20 武田薬品工業株式会社 口腔内崩壊錠
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CA2857457C (en) 2011-11-30 2018-05-01 Takeda Pharmaceutical Company Limited Dry coated tablet
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
HK1221899A1 (en) 2013-05-21 2017-06-16 Takeda Pharmaceutical Company Limited Oral disintegrating tablets
CN103539728A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种拉唑类药物中间体氯甲基吡啶衍生物的合成方法
CN103539729A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种氯甲基吡啶衍生物的工业化生产方法
CN104829594A (zh) * 2015-05-15 2015-08-12 苗怡文 一种治疗胃溃疡的药物兰索拉唑化合物
CN104817492B (zh) * 2015-05-22 2018-05-18 抚州三和医药化工有限公司 兰索拉唑中间体2-羟甲基-3-甲基-4-(2,2,2-三氟乙氧基）吡啶的分离纯化方法
KR102649498B1 (ko) 2023-12-06 2024-03-20 거산해운(주) 선사별 실시간 통합 예약 정보를 기반으로 한 화주의 해상 운송 예약 자동화 플랫폼 서비스 제공 방법, 장치 및 시스템

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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
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DE4018642C2 (de) * 1990-06-11 1993-11-25 Byk Gulden Lomberg Chem Fab Neue Salzform des 5-Difluormethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]-1H-benzimitazol-Natriumsalzes
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
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GB2297550C2 (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives

Also Published As

Publication number Publication date
WO1998021201A1 (en) 1998-05-22
HK1020194A1 (en) 2000-03-31
KR20000053158A (ko) 2000-08-25
DK0944617T3 (da) 2003-09-01
CN1237167A (zh) 1999-12-01
CN100355749C (zh) 2007-12-19
EP0944617A1 (de) 1999-09-29
DE69722027T2 (de) 2004-03-25
CN1171885C (zh) 2004-10-20
DE69722027D1 (de) 2003-06-18
ID21547A (id) 1999-06-24
AU731776B2 (en) 2001-04-05
US6002011A (en) 1999-12-14
ZA9710255B (en) 1999-05-13
CA2269053A1 (en) 1998-05-22
TR199901055T2 (xx) 1999-07-21
AU4965297A (en) 1998-06-03
CA2269053C (en) 2006-07-18
IL129724A0 (en) 2000-02-29
PT944617E (pt) 2003-08-29
TW385306B (en) 2000-03-21
NZ335145A (en) 2000-12-22
CN1616457A (zh) 2005-05-18
ES2199356T3 (es) 2004-02-16
IL129724A (en) 2004-02-19
KR100519576B1 (ko) 2005-10-07
EP0944617B1 (de) 2003-05-14

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