PT944617E - Cristais de derivados de benzimidazole e sua producao - Google Patents

Cristais de derivados de benzimidazole e sua producao

Info

Publication number
PT944617E
PT944617E PT97912445T PT97912445T PT944617E PT 944617 E PT944617 E PT 944617E PT 97912445 T PT97912445 T PT 97912445T PT 97912445 T PT97912445 T PT 97912445T PT 944617 E PT944617 E PT 944617E
Authority
PT
Portugal
Prior art keywords
crystals
production
substituted
optionally
benzimidazole derivatives
Prior art date
Application number
PT97912445T
Other languages
English (en)
Inventor
Masayasu Kato
Toru Ishida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17920069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT944617(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of PT944617E publication Critical patent/PT944617E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT97912445T 1996-11-14 1997-11-13 Cristais de derivados de benzimidazole e sua producao PT944617E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30336196 1996-11-14

Publications (1)

Publication Number Publication Date
PT944617E true PT944617E (pt) 2003-08-29

Family

ID=17920069

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97912445T PT944617E (pt) 1996-11-14 1997-11-13 Cristais de derivados de benzimidazole e sua producao

Country Status (19)

Country Link
US (1) US6002011A (pt)
EP (1) EP0944617B1 (pt)
KR (1) KR100519576B1 (pt)
CN (2) CN100355749C (pt)
AT (1) ATE240314T1 (pt)
AU (1) AU731776B2 (pt)
CA (1) CA2269053C (pt)
DE (1) DE69722027T2 (pt)
DK (1) DK0944617T3 (pt)
ES (1) ES2199356T3 (pt)
HK (1) HK1020194A1 (pt)
ID (1) ID21547A (pt)
IL (1) IL129724A (pt)
NZ (1) NZ335145A (pt)
PT (1) PT944617E (pt)
TR (1) TR199901055T2 (pt)
TW (1) TW385306B (pt)
WO (1) WO1998021201A1 (pt)
ZA (1) ZA9710255B (pt)

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IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
DE50012015D1 (de) * 1999-02-04 2006-03-30 Joern Bullerdiek Mittel zur prävention und/oder behandlung einer gewebeveränderung mesenchymalen ursprungs
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
PL333847A1 (en) * 1999-06-18 2001-01-02 Inst Farmaceutyczny Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
DE60020967T2 (de) 1999-06-30 2006-05-04 Takeda Pharmaceutical Co. Ltd. Kristalle von lansoprazole
ES2511774T3 (es) 2000-05-15 2014-10-23 Takeda Pharmaceutical Company Limited Formas cristalinas de (R)-lansoprazol
EP1306375B1 (en) * 2000-08-04 2006-10-11 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and application thereof
WO2002015908A1 (fr) 2000-08-18 2002-02-28 Takeda Chemical Industries, Ltd. Injections
HU229356B1 (en) 2000-12-01 2013-11-28 Takeda Pharmaceutical Process for the crystallization of (r)- or (s)-lansoprazole
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
DK2258351T3 (da) 2001-10-17 2013-08-26 Takeda Pharmaceutical Granula indeholdende lansoprazol i stor mængde
WO2003070665A2 (en) * 2002-02-19 2003-08-28 Teva Pharmaceutical Industries Ltd. Desolvating solvates of atorvastatin hemi-calcium
EP1476442A2 (en) * 2002-03-27 2004-11-17 Teva Pharmaceutical Industries Ltd. Lansoprazole polymorphs and processes for preparation thereof
KR100873419B1 (ko) * 2002-06-18 2008-12-11 페어차일드코리아반도체 주식회사 높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
EP1501824B1 (en) * 2002-08-21 2007-10-10 Teva Pharmaceutical Industries Ltd A method for the purification of lansoprazole
EP1837335A1 (en) * 2002-08-21 2007-09-26 Teva Pharmaceutical Industries Ltd A method for the purification of Lansoprazole
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
EP1552833B1 (en) 2002-10-16 2016-12-28 Takeda Pharmaceutical Company Limited Process for producing an amorphous optically active isomer of lansoprazole
EP1743893A1 (en) 2002-11-18 2007-01-17 Teva Pharmaceutical Industries Ltd. Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
DE03789888T1 (de) * 2002-11-18 2005-08-18 Teva Pharmaceutical Industries Ltd. Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
US7678816B2 (en) * 2003-02-05 2010-03-16 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
TW200526268A (en) * 2003-12-17 2005-08-16 Takeda Pharmaceutical Injectable composition
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
JP5563735B2 (ja) 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
US8592598B2 (en) * 2004-09-13 2013-11-26 Takeda Pharmaceutical Company Limited Method of producing a crystal of an imidazole compound
EP1681056A1 (en) 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Process for preparing lansoprazole
ES2675581T3 (es) 2005-02-25 2018-07-11 Takeda Pharmaceutical Company Limited Método para producir gránulos de un compuesto de bencimidazol recubiertos
WO2006132217A1 (ja) * 2005-06-07 2006-12-14 Takeda Pharmaceutical Company Limited ベンズイミダゾール化合物の塩の結晶
EP1903039A4 (en) * 2005-06-13 2010-09-22 Takeda Pharmaceutical INJECTION
RU2496480C2 (ru) 2005-12-28 2013-10-27 Такеда Фармасьютикал Компани Лимитед Твердый препарат с контролируемым высвобождением
KR100758600B1 (ko) * 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
US8129536B2 (en) * 2006-09-22 2012-03-06 Orchid Chemicals & Pharmaceuticals Limited Method for the purification of lansoprazole
US20100093804A1 (en) * 2006-12-07 2010-04-15 Hetero Drugs Limited novel crystalline form of lansoprazole
ITMI20062481A1 (it) * 2006-12-22 2008-06-23 Recordati Chem Pharm Processo per la preparazione di lansoprazolo forma i microcristallino
US9486446B2 (en) 2006-12-28 2016-11-08 Takeda Pharmaceutical Company Limited Orally disintegrating solid preparation
EP2573082A1 (en) * 2007-12-31 2013-03-27 Takeda Pharmaceutical Company Limited Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
CA2671369C (en) * 2008-03-10 2011-05-10 Takeda Pharmaceutical Company Limited Crystal of benzimidazole compound
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
US20130012714A1 (en) * 2010-02-11 2013-01-10 Orchid Chemicals & Pharmaceuticals Limited Novel solvate of dexlansoprazole
EP2647381A4 (en) 2010-12-03 2015-12-23 Takeda Pharmaceutical MELTING TABLET
TW201304823A (zh) 2010-12-27 2013-02-01 Takeda Pharmaceutical 口腔內崩壞錠
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
UY34478A (es) 2011-11-30 2013-06-28 Takeda Pharmaceutical Comprimido recubierto seco
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
CA2913106A1 (en) 2013-05-21 2014-11-27 Takeda Pharmaceutical Company Limited Orally disintegrable tablet
CN103539729A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种氯甲基吡啶衍生物的工业化生产方法
CN103539728A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种拉唑类药物中间体氯甲基吡啶衍生物的合成方法
CN104829594A (zh) * 2015-05-15 2015-08-12 苗怡文 一种治疗胃溃疡的药物兰索拉唑化合物
CN104817492B (zh) * 2015-05-22 2018-05-18 抚州三和医药化工有限公司 兰索拉唑中间体2-羟甲基-3-甲基-4-(2,2,2-三氟乙氧基）吡啶的分离纯化方法
KR102649498B1 (ko) 2023-12-06 2024-03-20 거산해운(주) 선사별 실시간 통합 예약 정보를 기반으로 한 화주의 해상 운송 예약 자동화 플랫폼 서비스 제공 방법, 장치 및 시스템

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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
DE4018642C2 (de) * 1990-06-11 1993-11-25 Byk Gulden Lomberg Chem Fab Neue Salzform des 5-Difluormethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]-1H-benzimitazol-Natriumsalzes
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
US5374730A (en) * 1993-11-04 1994-12-20 Torcan Chemical Ltd. Preparation of omeprazole and lansoprazole
GB2297550C2 (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives

Also Published As

Publication number Publication date
TR199901055T2 (xx) 1999-07-21
KR20000053158A (ko) 2000-08-25
WO1998021201A1 (en) 1998-05-22
CA2269053A1 (en) 1998-05-22
ZA9710255B (en) 1999-05-13
DE69722027D1 (de) 2003-06-18
CN1237167A (zh) 1999-12-01
HK1020194A1 (en) 2000-03-31
US6002011A (en) 1999-12-14
DE69722027T2 (de) 2004-03-25
ES2199356T3 (es) 2004-02-16
AU4965297A (en) 1998-06-03
NZ335145A (en) 2000-12-22
CN1616457A (zh) 2005-05-18
ATE240314T1 (de) 2003-05-15
ID21547A (id) 1999-06-24
AU731776B2 (en) 2001-04-05
CN100355749C (zh) 2007-12-19
KR100519576B1 (ko) 2005-10-07
DK0944617T3 (da) 2003-09-01
CA2269053C (en) 2006-07-18
IL129724A0 (en) 2000-02-29
TW385306B (en) 2000-03-21
CN1171885C (zh) 2004-10-20
EP0944617B1 (en) 2003-05-14
EP0944617A1 (en) 1999-09-29
IL129724A (en) 2004-02-19

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