PT99280A - Processo de preparacao de derivados do indolo e de composicoes farmaceuticas - Google Patents
Processo de preparacao de derivados do indolo e de composicoes farmaceuticasInfo
- Publication number
- PT99280A PT99280A PT99280A PT9928091A PT99280A PT 99280 A PT99280 A PT 99280A PT 99280 A PT99280 A PT 99280A PT 9928091 A PT9928091 A PT 9928091A PT 99280 A PT99280 A PT 99280A
- Authority
- PT
- Portugal
- Prior art keywords
- indoor
- pct
- preparation
- hydrogen
- pharmaceutical compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909022858A GB9022858D0 (en) | 1990-10-20 | 1990-10-20 | Derivatives of indoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99280A true PT99280A (pt) | 1992-08-31 |
| PT99280B PT99280B (pt) | 1999-04-30 |
Family
ID=10684077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99280A PT99280B (pt) | 1990-10-20 | 1991-10-18 | Processo de preparacao de derivados do indolo e de composicoes farmaceuticas |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5385919A (pt) |
| EP (1) | EP0553218B1 (pt) |
| JP (1) | JPH06501945A (pt) |
| AT (1) | ATE181327T1 (pt) |
| AU (1) | AU648351B2 (pt) |
| CA (1) | CA2094383A1 (pt) |
| DE (1) | DE69131353T2 (pt) |
| GB (1) | GB9022858D0 (pt) |
| IE (1) | IE63139B1 (pt) |
| IL (1) | IL99777A0 (pt) |
| NZ (1) | NZ240120A (pt) |
| PT (1) | PT99280B (pt) |
| WO (1) | WO1992006972A1 (pt) |
| ZA (1) | ZA918083B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999032482A1 (en) * | 1997-12-19 | 1999-07-01 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| EP1266897A3 (en) * | 1997-12-19 | 2003-12-03 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| US6410562B1 (en) | 1998-12-18 | 2002-06-25 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| CA2590894A1 (en) * | 2005-01-14 | 2006-07-20 | Teva Pharmaceutical Industries Ltd. | Preparation of crude candesartan cilexetil |
| CN104395314A (zh) | 2012-06-20 | 2015-03-04 | 霍夫曼-拉罗奇有限公司 | 端锚聚合酶抑制剂吡咯并吡嗪酮 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE528814A (pt) * | 1953-05-13 | |||
| US4328345A (en) * | 1978-10-02 | 1982-05-04 | Schering Corporation | Pyridyl substituted indoles |
| US4436746A (en) * | 1982-09-30 | 1984-03-13 | Ciba-Geigy Corporation | Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles |
| EP0141686B1 (fr) * | 1983-08-11 | 1987-09-09 | Synthelabo | Dérivés de l'indole, leur préparation et leur application en thérapeutique |
| US5017584A (en) * | 1984-12-20 | 1991-05-21 | Sterling Drug Inc. | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas |
| EP0211698B1 (fr) * | 1985-02-08 | 1991-01-30 | Synthelabo | Dérivés de (dihydro-4,5 1H-imidazolyl-2)-2 dihydro-2,3 indole, leur préparation et leur application en thérapeutique |
| US4912125A (en) * | 1985-09-03 | 1990-03-27 | Ciba-Geigy Corporation | 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles for reducing intraocular pressure |
| US4908376A (en) * | 1985-09-03 | 1990-03-13 | Ciba-Geigy Corporation | 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles in composition form for reducing intraocular pressure |
| DE3824658A1 (de) * | 1988-07-15 | 1990-01-18 | Schering Ag | N-hetaryl-imidazolderivate |
| JP2722586B2 (ja) * | 1989-01-13 | 1998-03-04 | 大正製薬株式会社 | インドリルイミダゾール誘導体 |
| PT95899A (pt) * | 1989-11-17 | 1991-09-13 | Glaxo Group Ltd | Processo para a preparacao de derivados indole |
-
1990
- 1990-10-20 GB GB909022858A patent/GB9022858D0/en active Pending
-
1991
- 1991-09-26 IE IE339391A patent/IE63139B1/en not_active IP Right Cessation
- 1991-10-07 NZ NZ240120A patent/NZ240120A/en unknown
- 1991-10-09 ZA ZA918083A patent/ZA918083B/xx unknown
- 1991-10-10 AU AU86681/91A patent/AU648351B2/en not_active Ceased
- 1991-10-10 US US08/039,232 patent/US5385919A/en not_active Expired - Fee Related
- 1991-10-10 JP JP3516463A patent/JPH06501945A/ja active Pending
- 1991-10-10 DE DE69131353T patent/DE69131353T2/de not_active Expired - Fee Related
- 1991-10-10 CA CA002094383A patent/CA2094383A1/en not_active Abandoned
- 1991-10-10 AT AT91919221T patent/ATE181327T1/de not_active IP Right Cessation
- 1991-10-10 WO PCT/GB1991/001756 patent/WO1992006972A1/en not_active Ceased
- 1991-10-10 EP EP91919221A patent/EP0553218B1/en not_active Expired - Lifetime
- 1991-10-17 IL IL99777A patent/IL99777A0/xx unknown
- 1991-10-18 PT PT99280A patent/PT99280B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE913393A1 (en) | 1992-04-22 |
| AU648351B2 (en) | 1994-04-21 |
| DE69131353D1 (de) | 1999-07-22 |
| GB9022858D0 (en) | 1990-12-05 |
| WO1992006972A1 (en) | 1992-04-30 |
| EP0553218B1 (en) | 1999-06-16 |
| IL99777A0 (en) | 1992-08-18 |
| US5385919A (en) | 1995-01-31 |
| CA2094383A1 (en) | 1992-04-21 |
| DE69131353T2 (de) | 1999-10-14 |
| NZ240120A (en) | 1993-10-26 |
| AU8668191A (en) | 1992-05-20 |
| IE63139B1 (en) | 1995-03-22 |
| EP0553218A1 (en) | 1993-08-04 |
| ZA918083B (en) | 1992-12-30 |
| JPH06501945A (ja) | 1994-03-03 |
| PT99280B (pt) | 1999-04-30 |
| ATE181327T1 (de) | 1999-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920422 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990112 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000731 |