DE69131353T2 - Indolderivate - Google Patents

Indolderivate

Info

Publication number
DE69131353T2
DE69131353T2 DE69131353T DE69131353T DE69131353T2 DE 69131353 T2 DE69131353 T2 DE 69131353T2 DE 69131353 T DE69131353 T DE 69131353T DE 69131353 T DE69131353 T DE 69131353T DE 69131353 T2 DE69131353 T2 DE 69131353T2
Authority
DE
Germany
Prior art keywords
pct
hydrogen
date
pyridyl
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131353T
Other languages
English (en)
Other versions
DE69131353D1 (de
Inventor
Christopher Chapleo
Gay Fagan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Reckitt and Colman Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt and Colman Products Ltd filed Critical Reckitt and Colman Products Ltd
Publication of DE69131353D1 publication Critical patent/DE69131353D1/de
Application granted granted Critical
Publication of DE69131353T2 publication Critical patent/DE69131353T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
DE69131353T 1990-10-20 1991-10-10 Indolderivate Expired - Fee Related DE69131353T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909022858A GB9022858D0 (en) 1990-10-20 1990-10-20 Derivatives of indoles
PCT/GB1991/001756 WO1992006972A1 (en) 1990-10-20 1991-10-10 Indole derivatives

Publications (2)

Publication Number Publication Date
DE69131353D1 DE69131353D1 (de) 1999-07-22
DE69131353T2 true DE69131353T2 (de) 1999-10-14

Family

ID=10684077

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131353T Expired - Fee Related DE69131353T2 (de) 1990-10-20 1991-10-10 Indolderivate

Country Status (14)

Country Link
US (1) US5385919A (de)
EP (1) EP0553218B1 (de)
JP (1) JPH06501945A (de)
AT (1) ATE181327T1 (de)
AU (1) AU648351B2 (de)
CA (1) CA2094383A1 (de)
DE (1) DE69131353T2 (de)
GB (1) GB9022858D0 (de)
IE (1) IE63139B1 (de)
IL (1) IL99777A0 (de)
NZ (1) NZ240120A (de)
PT (1) PT99280B (de)
WO (1) WO1992006972A1 (de)
ZA (1) ZA918083B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1266897A3 (de) * 1997-12-19 2003-12-03 Eli Lilly And Company Hypoglykämische Imidazolinderivate
WO1999032482A1 (en) * 1997-12-19 1999-07-01 Eli Lilly And Company Hypoglycemic imidazoline compounds
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
CN101103021A (zh) * 2005-01-14 2008-01-09 特瓦制药工业有限公司 粗坎地沙坦西酯的制备
EP2864330A1 (de) 2012-06-20 2015-04-29 F. Hoffmann-La Roche AG Pyrrolopyrazoninhibitoren von tankyrase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE528814A (de) * 1953-05-13
US4328345A (en) * 1978-10-02 1982-05-04 Schering Corporation Pyridyl substituted indoles
US4436746A (en) * 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
EP0141686B1 (de) * 1983-08-11 1987-09-09 Synthelabo Indol-Derivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung
US5017584A (en) * 1984-12-20 1991-05-21 Sterling Drug Inc. Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas
EP0211698B1 (de) * 1985-02-08 1991-01-30 Synthelabo (Dihydro-4,5-1H-imidazolyl-2)-2-dihydro-2,3-indolderivate, ihre Herstellung und Anwendung als Heilmittel
US4912125A (en) * 1985-09-03 1990-03-27 Ciba-Geigy Corporation 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles for reducing intraocular pressure
US4908376A (en) * 1985-09-03 1990-03-13 Ciba-Geigy Corporation 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles in composition form for reducing intraocular pressure
DE3824658A1 (de) * 1988-07-15 1990-01-18 Schering Ag N-hetaryl-imidazolderivate
JP2722586B2 (ja) * 1989-01-13 1998-03-04 大正製薬株式会社 インドリルイミダゾール誘導体
PT95899A (pt) * 1989-11-17 1991-09-13 Glaxo Group Ltd Processo para a preparacao de derivados indole

Also Published As

Publication number Publication date
CA2094383A1 (en) 1992-04-21
NZ240120A (en) 1993-10-26
JPH06501945A (ja) 1994-03-03
IE913393A1 (en) 1992-04-22
EP0553218B1 (de) 1999-06-16
WO1992006972A1 (en) 1992-04-30
PT99280B (pt) 1999-04-30
PT99280A (pt) 1992-08-31
GB9022858D0 (en) 1990-12-05
AU8668191A (en) 1992-05-20
EP0553218A1 (de) 1993-08-04
DE69131353D1 (de) 1999-07-22
AU648351B2 (en) 1994-04-21
IL99777A0 (en) 1992-08-18
IE63139B1 (en) 1995-03-22
ZA918083B (en) 1992-12-30
ATE181327T1 (de) 1999-07-15
US5385919A (en) 1995-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee