ZA918083B - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
ZA918083B
ZA918083B ZA918083A ZA918083A ZA918083B ZA 918083 B ZA918083 B ZA 918083B ZA 918083 A ZA918083 A ZA 918083A ZA 918083 A ZA918083 A ZA 918083A ZA 918083 B ZA918083 B ZA 918083B
Authority
ZA
South Africa
Prior art keywords
pct
hydrogen
date
indole derivatives
pyridyl
Prior art date
Application number
ZA918083A
Other languages
English (en)
Inventor
Christopher Bourne Chapleo
Bourne Chapleo Christopher
Gay Patricia Fagan
Patricia Fagan Gay
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of ZA918083B publication Critical patent/ZA918083B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA918083A 1990-10-20 1991-10-09 Indole derivatives ZA918083B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909022858A GB9022858D0 (en) 1990-10-20 1990-10-20 Derivatives of indoles

Publications (1)

Publication Number Publication Date
ZA918083B true ZA918083B (en) 1992-12-30

Family

ID=10684077

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918083A ZA918083B (en) 1990-10-20 1991-10-09 Indole derivatives

Country Status (14)

Country Link
US (1) US5385919A (de)
EP (1) EP0553218B1 (de)
JP (1) JPH06501945A (de)
AT (1) ATE181327T1 (de)
AU (1) AU648351B2 (de)
CA (1) CA2094383A1 (de)
DE (1) DE69131353T2 (de)
GB (1) GB9022858D0 (de)
IE (1) IE63139B1 (de)
IL (1) IL99777A0 (de)
NZ (1) NZ240120A (de)
PT (1) PT99280B (de)
WO (1) WO1992006972A1 (de)
ZA (1) ZA918083B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2315226A1 (en) * 1997-12-19 1999-07-01 Eli Lilly And Company Hypoglycemic imidazoline compounds
EP1266897A3 (de) * 1997-12-19 2003-12-03 Eli Lilly And Company Hypoglykämische Imidazolinderivate
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
EP1836195A2 (de) * 2005-01-14 2007-09-26 Teva Pharmaceutical Industries Ltd Herstellung von rohem candesartan-cilexetil
CA2870062A1 (en) 2012-06-20 2013-12-27 F.Hoffmann-La Roche Ag Pyrrolopyrazone inhibitors of tankyrase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE528814A (de) * 1953-05-13
US4328345A (en) * 1978-10-02 1982-05-04 Schering Corporation Pyridyl substituted indoles
US4436746A (en) * 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
ATE29494T1 (de) * 1983-08-11 1987-09-15 Synthelabo Indol-derivate, verfahren zu deren herstellung und deren therapeutische anwendung.
US5017584A (en) * 1984-12-20 1991-05-21 Sterling Drug Inc. Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas
EP0211698B1 (de) * 1985-02-08 1991-01-30 Synthelabo (Dihydro-4,5-1H-imidazolyl-2)-2-dihydro-2,3-indolderivate, ihre Herstellung und Anwendung als Heilmittel
US4908376A (en) * 1985-09-03 1990-03-13 Ciba-Geigy Corporation 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles in composition form for reducing intraocular pressure
US4912125A (en) * 1985-09-03 1990-03-27 Ciba-Geigy Corporation 2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles for reducing intraocular pressure
DE3824658A1 (de) * 1988-07-15 1990-01-18 Schering Ag N-hetaryl-imidazolderivate
JP2722586B2 (ja) * 1989-01-13 1998-03-04 大正製薬株式会社 インドリルイミダゾール誘導体
PT95899A (pt) * 1989-11-17 1991-09-13 Glaxo Group Ltd Processo para a preparacao de derivados indole

Also Published As

Publication number Publication date
CA2094383A1 (en) 1992-04-21
NZ240120A (en) 1993-10-26
ATE181327T1 (de) 1999-07-15
EP0553218B1 (de) 1999-06-16
AU8668191A (en) 1992-05-20
GB9022858D0 (en) 1990-12-05
JPH06501945A (ja) 1994-03-03
IL99777A0 (en) 1992-08-18
EP0553218A1 (de) 1993-08-04
AU648351B2 (en) 1994-04-21
PT99280B (pt) 1999-04-30
US5385919A (en) 1995-01-31
IE913393A1 (en) 1992-04-22
WO1992006972A1 (en) 1992-04-30
IE63139B1 (en) 1995-03-22
DE69131353D1 (de) 1999-07-22
DE69131353T2 (de) 1999-10-14
PT99280A (pt) 1992-08-31

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