ATE75737T1 - Indenothiazolderivate und verfahren zu ihrer herstellung. - Google Patents
Indenothiazolderivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE75737T1 ATE75737T1 AT87200041T AT87200041T ATE75737T1 AT E75737 T1 ATE75737 T1 AT E75737T1 AT 87200041 T AT87200041 T AT 87200041T AT 87200041 T AT87200041 T AT 87200041T AT E75737 T1 ATE75737 T1 AT E75737T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- low alkyl
- unsubstituted
- alkyl group
- Prior art date
Links
- IDUZNWHHEUJEBT-UHFFFAOYSA-N 2H-indeno[1,2-d][1,3]thiazole Chemical class C1=CC=C2C3=NCSC3=CC2=C1 IDUZNWHHEUJEBT-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP764086 | 1986-01-16 | ||
| EP87200041A EP0230334B1 (de) | 1986-01-16 | 1987-01-14 | Indenothiazolderivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE75737T1 true ATE75737T1 (de) | 1992-05-15 |
Family
ID=11671425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87200041T ATE75737T1 (de) | 1986-01-16 | 1987-01-14 | Indenothiazolderivate und verfahren zu ihrer herstellung. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4877876A (de) |
| EP (1) | EP0230334B1 (de) |
| JP (1) | JPH0667919B2 (de) |
| KR (1) | KR900003368B1 (de) |
| CN (1) | CN87100171A (de) |
| AT (1) | ATE75737T1 (de) |
| AU (1) | AU598229B2 (de) |
| CA (1) | CA1292226C (de) |
| DE (1) | DE3778714D1 (de) |
| ES (1) | ES2038166T3 (de) |
| SU (1) | SU1609449A3 (de) |
| WO (1) | WO1987004434A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0513387T3 (da) * | 1990-11-30 | 2000-06-05 | Otsuka Pharma Co Ltd | Thiazolderivater som inhibitorer af aktivt oxygen |
| US5834499A (en) * | 1994-03-11 | 1998-11-10 | Yamanouchi Pharmaceutical Co., Ltd. | 5-HT3 receptor agonist, novel thiazole derivative and intermediate thereof |
| TW416953B (en) | 1996-09-25 | 2001-01-01 | Takeda Chemical Industries Ltd | Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use |
| DE19844547C2 (de) * | 1998-09-29 | 2002-11-07 | Aventis Pharma Gmbh | Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE19908538A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen |
| DE19908537A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Verwendung von polycyclischen 2-Amino-Thiazol Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas |
| OA11941A (en) | 1999-05-10 | 2006-04-12 | Warner Lambert Co | Aromatic amides. |
| RU2252219C2 (ru) * | 1999-11-05 | 2005-05-20 | Авентис Фарма Дойчланд Гмбх | Производные индено-, нафто- и бензоциклогептадигидротиазола, их получение и их применение в качестве анорексических лекарственных средств |
| YU56302A (sh) * | 2000-02-23 | 2005-11-28 | Aventis Pharma Deutschland Gmbh. | Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstva |
| DE10008274A1 (de) * | 2000-02-23 | 2001-08-30 | Aventis Pharma Gmbh | Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| NZ520981A (en) * | 2000-02-26 | 2004-08-27 | Aventis Pharma Gmbh | 8,8a-dihydro-indeno[1,2-d]thiazole derivatives with a sulphonamido or sulphono substituent in the 2 position, a method for production thereof and use thereof as a medicament |
| US7732484B2 (en) * | 2000-08-01 | 2010-06-08 | University Of Virginia Patent Foundation | Use of selective adenosine A1 receptor allosteric enhancers to manipulate angiogenesis |
| US7485655B2 (en) * | 2002-01-16 | 2009-02-03 | University Of Virginia Patent Foundation | 2-Aminothiazole allosteric enhancers of A1 adenosine receptors |
| WO2006013054A1 (en) * | 2004-08-05 | 2006-02-09 | F. Hoffmann-La Roche Ag | Substituted n-acyl-2-aminothiazoles |
| TWI402261B (zh) | 2006-06-19 | 2013-07-21 | Takeda Pharmaceutical | 三環化合物及其醫藥組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082773A (en) * | 1972-07-03 | 1978-04-04 | E. R. Squibb & Sons, Inc. | Tricyclic tetrahydro naphthaleneols and related compounds |
| US4321372A (en) * | 1980-06-16 | 1982-03-23 | Pfizer Inc. | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides |
| DE3027528A1 (de) * | 1980-07-19 | 1982-02-18 | Basf Ag, 6700 Ludwigshafen | Ueberbrueckte thiazolyloxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
-
1987
- 1987-01-13 CA CA000527229A patent/CA1292226C/en not_active Expired - Fee Related
- 1987-01-14 AU AU68420/87A patent/AU598229B2/en not_active Ceased
- 1987-01-14 KR KR1019870700826A patent/KR900003368B1/ko not_active Expired
- 1987-01-14 EP EP87200041A patent/EP0230334B1/de not_active Expired - Lifetime
- 1987-01-14 US US07/107,600 patent/US4877876A/en not_active Expired - Fee Related
- 1987-01-14 JP JP62006820A patent/JPH0667919B2/ja not_active Expired - Lifetime
- 1987-01-14 DE DE8787200041T patent/DE3778714D1/de not_active Expired - Fee Related
- 1987-01-14 AT AT87200041T patent/ATE75737T1/de not_active IP Right Cessation
- 1987-01-14 ES ES198787200041T patent/ES2038166T3/es not_active Expired - Lifetime
- 1987-01-14 WO PCT/JP1987/000021 patent/WO1987004434A1/ja not_active Ceased
- 1987-01-15 CN CN198787100171A patent/CN87100171A/zh active Pending
- 1987-09-15 SU SU874203319A patent/SU1609449A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1987004434A1 (fr) | 1987-07-30 |
| JPS62252780A (ja) | 1987-11-04 |
| JPH0667919B2 (ja) | 1994-08-31 |
| CN87100171A (zh) | 1988-01-20 |
| US4877876A (en) | 1989-10-31 |
| KR900003368B1 (ko) | 1990-05-16 |
| EP0230334B1 (de) | 1992-05-06 |
| ES2038166T3 (es) | 1993-07-16 |
| KR880700798A (ko) | 1988-04-12 |
| EP0230334A1 (de) | 1987-07-29 |
| CA1292226C (en) | 1991-11-19 |
| AU6842087A (en) | 1987-08-14 |
| AU598229B2 (en) | 1990-06-21 |
| SU1609449A3 (ru) | 1990-11-23 |
| DE3778714D1 (de) | 1992-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |