YU56302A - Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstva - Google Patents
Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstvaInfo
- Publication number
- YU56302A YU56302A YU56302A YUP56302A YU56302A YU 56302 A YU56302 A YU 56302A YU 56302 A YU56302 A YU 56302A YU P56302 A YUP56302 A YU P56302A YU 56302 A YU56302 A YU 56302A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- production
- derivatives
- indeno
- thiazol
- medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Fuses (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
Abstract
Pronalazak se odnosi na policiklične dihidrotiazole kao i na njihove fiziološki prihvatljive soli i fiziološki funkcionalne derivate. Opisuju se jedinjenja Formule I u kojoj ostaci imaju navedena značenja, kao i njihove fiziološki prihvatljive soli i postupak za njihovu proizvodnju. Ova jedinjenja su pogodna naprimer kao anorektična sredstva.[The invention relates to polycyclic dihydrothiazoles and to their physiologically compatible salts and physiologically functional derivatives. The invention relates to compounds of formula (I), wherein the groups have the given meanings, to their physiologically compatible salts and to a method for their production. The compounds are, for example, suitable for use as anorectic agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10008275 | 2000-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU56302A true YU56302A (sh) | 2005-11-28 |
Family
ID=7631989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU56302A YU56302A (sh) | 2000-02-23 | 2001-02-12 | Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstva |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6403624B1 (sh) |
| EP (1) | EP1259498B1 (sh) |
| JP (1) | JP4898052B2 (sh) |
| KR (1) | KR20020079891A (sh) |
| CN (1) | CN1195747C (sh) |
| AT (1) | ATE283265T1 (sh) |
| AU (1) | AU781003B2 (sh) |
| BR (1) | BR0108605A (sh) |
| CA (1) | CA2400698A1 (sh) |
| CZ (1) | CZ20022838A3 (sh) |
| DE (1) | DE50104600D1 (sh) |
| EE (1) | EE200200466A (sh) |
| ES (1) | ES2231482T3 (sh) |
| HK (1) | HK1055117A1 (sh) |
| HR (1) | HRP20020688A2 (sh) |
| HU (1) | HUP0300140A3 (sh) |
| IL (1) | IL151327A0 (sh) |
| MX (1) | MXPA02007021A (sh) |
| NO (1) | NO20023978L (sh) |
| NZ (1) | NZ520926A (sh) |
| PL (1) | PL357547A1 (sh) |
| PT (1) | PT1259498E (sh) |
| RU (1) | RU2261860C2 (sh) |
| SK (1) | SK12162002A3 (sh) |
| WO (1) | WO2001062746A1 (sh) |
| YU (1) | YU56302A (sh) |
| ZA (1) | ZA200206487B (sh) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10142660A1 (de) | 2001-08-31 | 2003-03-20 | Aventis Pharma Gmbh | Verwendung von Derivaten von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas |
| DE10142659A1 (de) * | 2001-08-31 | 2003-03-20 | Aventis Pharma Gmbh | Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US20080125403A1 (en) | 2004-04-02 | 2008-05-29 | Merck & Co., Inc. | Method of Treating Men with Metabolic and Anthropometric Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| CN102264228A (zh) | 2008-10-22 | 2011-11-30 | 默沙东公司 | 用于抗糖尿病药的新的环状苯并咪唑衍生物 |
| US8329914B2 (en) | 2008-10-31 | 2012-12-11 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| WO2011106273A1 (en) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA2826649C (en) | 2011-02-25 | 2016-07-26 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| WO2012118972A2 (en) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| US20140045746A1 (en) | 2012-08-02 | 2014-02-13 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| BR112015019836A2 (pt) | 2013-02-22 | 2017-07-18 | Merck Sharp & Dohme | composto, composição farmacêutica, e, uso de um composto |
| US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CN113388007A (zh) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| US11072602B2 (en) | 2016-12-06 | 2021-07-27 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| EP3558298A4 (en) | 2016-12-20 | 2020-08-05 | Merck Sharp & Dohme Corp. | ANTIDIABETIC SPIROCHROMAN COMPOUNDS |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2640358A1 (de) | 1976-09-08 | 1978-03-16 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
| GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
| DE19844547C2 (de) * | 1998-09-29 | 2002-11-07 | Aventis Pharma Gmbh | Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE19908539A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
-
2001
- 2001-02-12 BR BR0108605-7A patent/BR0108605A/pt not_active IP Right Cessation
- 2001-02-12 WO PCT/EP2001/001499 patent/WO2001062746A1/de not_active Application Discontinuation
- 2001-02-12 CZ CZ20022838A patent/CZ20022838A3/cs unknown
- 2001-02-12 JP JP2001562528A patent/JP4898052B2/ja not_active Expired - Fee Related
- 2001-02-12 ES ES01929342T patent/ES2231482T3/es not_active Expired - Lifetime
- 2001-02-12 HU HU0300140A patent/HUP0300140A3/hu unknown
- 2001-02-12 CN CNB018054919A patent/CN1195747C/zh not_active Expired - Fee Related
- 2001-02-12 PL PL01357547A patent/PL357547A1/xx not_active Application Discontinuation
- 2001-02-12 AU AU56153/01A patent/AU781003B2/en not_active Ceased
- 2001-02-12 EE EEP200200466A patent/EE200200466A/xx unknown
- 2001-02-12 IL IL15132701A patent/IL151327A0/xx unknown
- 2001-02-12 YU YU56302A patent/YU56302A/sh unknown
- 2001-02-12 CA CA002400698A patent/CA2400698A1/en not_active Abandoned
- 2001-02-12 PT PT01929342T patent/PT1259498E/pt unknown
- 2001-02-12 MX MXPA02007021A patent/MXPA02007021A/es active IP Right Grant
- 2001-02-12 NZ NZ520926A patent/NZ520926A/en unknown
- 2001-02-12 EP EP01929342A patent/EP1259498B1/de not_active Expired - Lifetime
- 2001-02-12 SK SK1216-2002A patent/SK12162002A3/sk unknown
- 2001-02-12 DE DE50104600T patent/DE50104600D1/de not_active Expired - Lifetime
- 2001-02-12 RU RU2002125460/04A patent/RU2261860C2/ru not_active IP Right Cessation
- 2001-02-12 AT AT01929342T patent/ATE283265T1/de not_active IP Right Cessation
- 2001-02-12 KR KR1020027011001A patent/KR20020079891A/ko not_active Application Discontinuation
- 2001-02-23 US US09/790,911 patent/US6403624B1/en not_active Expired - Lifetime
-
2002
- 2002-08-14 ZA ZA200206487A patent/ZA200206487B/en unknown
- 2002-08-21 NO NO20023978A patent/NO20023978L/no not_active Application Discontinuation
- 2002-08-22 HR HRP20020688 patent/HRP20020688A2/hr not_active Application Discontinuation
-
2003
- 2003-10-15 HK HK03107412A patent/HK1055117A1/xx not_active IP Right Cessation
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