JPS6463569A - Heteroaryl derivative - Google Patents
Heteroaryl derivativeInfo
- Publication number
- JPS6463569A JPS6463569A JP63064125A JP6412588A JPS6463569A JP S6463569 A JPS6463569 A JP S6463569A JP 63064125 A JP63064125 A JP 63064125A JP 6412588 A JP6412588 A JP 6412588A JP S6463569 A JPS6463569 A JP S6463569A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- compound
- atoms
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A compound of formula I [M is 5-7 membered heterocyclic group which contains 2N atoms and may be substituted, on its cyclic carbon atoms, with alkyl and oxo; A is formula II (X<1>, X<2> are H, halogen, where they are not H simultaneously); B is formula III (R<1> is H, alkyl; R<2>, R<3> are H, or incorporate to form oxo; Y is NR<5>; R<4>, R<5> are H, aryl, aralkyl, alkyl); A, B are different substituents of M on N atoms]. EXAMPLE:1-[Bis(4-fluorophenyl)methyl]-4-(1-naphthylaminocarbonylmethyl )pipe razine. USE:Cerebral metabolism improver. It has excellent calcium-inhibiting action and hypoxia-antagonistic action. PREPARATION:The reaction of an amino compound of the formula: A-M-H with an alkylating agent of formula IV (Xa is halogen, alkanesulfonyl, or the like) gives the compound of formula I.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63064125A JPS6463569A (en) | 1987-03-18 | 1988-03-17 | Heteroaryl derivative |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6315787 | 1987-03-18 | ||
| JP63064125A JPS6463569A (en) | 1987-03-18 | 1988-03-17 | Heteroaryl derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6463569A true JPS6463569A (en) | 1989-03-09 |
Family
ID=26404243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63064125A Pending JPS6463569A (en) | 1987-03-18 | 1988-03-17 | Heteroaryl derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6463569A (en) |
-
1988
- 1988-03-17 JP JP63064125A patent/JPS6463569A/en active Pending
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