ATE112773T1 - 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one. - Google Patents

5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.

Info

Publication number
ATE112773T1
ATE112773T1 AT89308506T AT89308506T ATE112773T1 AT E112773 T1 ATE112773 T1 AT E112773T1 AT 89308506 T AT89308506 T AT 89308506T AT 89308506 T AT89308506 T AT 89308506T AT E112773 T1 ATE112773 T1 AT E112773T1
Authority
AT
Austria
Prior art keywords
alkyl
beta
phenyl
amidomethyloxazolidine
substituted
Prior art date
Application number
AT89308506T
Other languages
German (de)
English (en)
Inventor
Steven L Brickner
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE112773T1 publication Critical patent/ATE112773T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT89308506T 1988-09-15 1989-08-22 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one. ATE112773T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24498888A 1988-09-15 1988-09-15
US25385088A 1988-10-05 1988-10-05
US32494289A 1989-03-17 1989-03-17

Publications (1)

Publication Number Publication Date
ATE112773T1 true ATE112773T1 (de) 1994-10-15

Family

ID=27399816

Family Applications (2)

Application Number Title Priority Date Filing Date
AT89308506T ATE112773T1 (de) 1988-09-15 1989-08-22 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
AT94102762T ATE201870T1 (de) 1988-09-15 1989-08-22 3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT94102762T ATE201870T1 (de) 1988-09-15 1989-08-22 3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one

Country Status (13)

Country Link
EP (3) EP0359418B1 (OSRAM)
JP (2) JP2865211B2 (OSRAM)
KR (1) KR0138262B1 (OSRAM)
AT (2) ATE112773T1 (OSRAM)
AU (1) AU617871B2 (OSRAM)
CA (1) CA1335103C (OSRAM)
DE (2) DE68918792T2 (OSRAM)
DK (2) DK175696B1 (OSRAM)
ES (1) ES2157934T3 (OSRAM)
GR (1) GR3036491T3 (OSRAM)
LV (1) LV12888B (OSRAM)
TW (1) TW219936B (OSRAM)
WO (1) WO1990002744A1 (OSRAM)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
DE69132691T2 (de) * 1990-06-07 2002-06-20 Astrazeneca Ab, Soedertaelje Indolderivate als 5-HT1-like Agonisten
CA2115029C (en) * 1991-08-14 2002-03-26 Stanford Salvatore Pelosi, Jr. Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
KR950702417A (ko) * 1992-07-08 1995-07-29 로렌스 티. 웰츠 마이코박테륨 투베르쿨로시스에 대해 유용한 5′-인돌리닐 옥사졸리디논(5′-indolinyl oxazolidinones useful against mycobacterium tuberculosis)
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
SI0788498T1 (en) * 1994-10-26 2001-12-31 Upjohn Co Phenyloxazolidinone antimicrobials
KR100392216B1 (ko) * 1994-11-15 2003-10-17 파마시아 앤드 업존 캄파니 이환상옥사진및티아진옥사졸리디논항세균물질
EP0807112B1 (en) * 1995-02-03 2001-09-05 PHARMACIA & UPJOHN COMPANY Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DK0828741T3 (da) * 1995-05-11 2001-11-26 Upjohn Co Spirocykliske og bicykliske diazinyl- og carbazinyloxazolidinoner
US5883093A (en) * 1995-09-12 1999-03-16 Pharmacia & Upjohn Company Phenyloxazolidinone antimicrobials
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19601265A1 (de) 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601264A1 (de) 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601627A1 (de) 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
RU2208613C2 (ru) 1997-05-30 2003-07-20 Фармация Энд Апджон Компани Оксазолидиноновые антибактериальные агенты, содержащие тиокарбонильную функциональную группу
DE19730847A1 (de) * 1997-07-18 1999-01-28 Bayer Ag Tricyclisch substituierte Oxazolidinone
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
US5998406A (en) * 1997-11-12 1999-12-07 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
CN1288462A (zh) 1998-01-23 2001-03-21 法玛西雅厄普约翰美国公司 噁唑烷酮组合库、组合物和制备方法
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
CA2374383A1 (en) * 1999-07-28 2001-02-08 Pharmacia & Upjohn Company Oxazolidinones and their use as antiinfectives
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
RU2292345C9 (ru) 2000-07-17 2007-05-10 Ранбакси Лабораторис Лимитед Производные оксазолидинона
EP1330459B1 (en) 2000-10-02 2006-08-02 Emory University Triptolide analogs for the treatment of autoimmune and inflammatory disorders
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
EP1781643A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxindole oxazolidinones as antibacterial agents
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
KR20070116989A (ko) * 2005-04-06 2007-12-11 파마시아 앤드 업존 캄파니 엘엘씨 항균제로서의 옥신돌 옥사졸리디논
NZ585752A (en) * 2007-12-24 2011-11-25 Cipla Ltd Process for the synthesis of propargylated aminoindan derivatives
US8598156B2 (en) 2010-03-25 2013-12-03 Glaxosmithkline Llc Chemical compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES533097A0 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
HK1002234A1 (en) 1998-08-07
DE68918792D1 (de) 1994-11-17
EP0609905A1 (en) 1994-08-10
ATE201870T1 (de) 2001-06-15
DE68918792T2 (de) 1995-03-30
AU4195789A (en) 1990-04-02
EP0434714A1 (en) 1991-07-03
EP0609905B1 (en) 2001-06-06
JP3188418B2 (ja) 2001-07-16
DE68929303D1 (de) 2001-07-12
DK200401246A (da) 2004-08-18
DK175696B1 (da) 2005-01-24
KR0138262B1 (ko) 1998-05-15
JP2865211B2 (ja) 1999-03-08
LV12888B (en) 2002-12-20
EP0359418B1 (en) 1994-10-12
TW219936B (OSRAM) 1994-02-01
EP0359418A1 (en) 1990-03-21
JPH1180139A (ja) 1999-03-26
CA1335103C (en) 1995-04-04
GR3036491T3 (en) 2001-11-30
JPH04500665A (ja) 1992-02-06
AU617871B2 (en) 1991-12-05
DK175940B1 (da) 2005-08-01
DK45591A (da) 1991-03-13
DK45591D0 (da) 1991-03-13
WO1990002744A1 (en) 1990-03-22
ES2157934T3 (es) 2001-09-01
KR900701780A (ko) 1990-12-04
DE68929303T2 (de) 2002-05-02

Similar Documents

Publication Publication Date Title
ATE112773T1 (de) 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
DE3879915D1 (de) Heterocyclische verbindungen.
CA2098301A1 (en) Certain aminomethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands
ATE135687T1 (de) Perhydroisoindolderivate, ihre herstellung und diese enthaltende arzneimittel
NO820264L (no) Fremgangsmaate for fremstilling av 2-penemforbindelser
FI931370A0 (fi) Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
BR9006840A (pt) Compostos heterociclicos
FI954131A0 (fi) Heterosykliset yhdisteet ja niiden valmistus ja käyttö
BR8807266A (pt) Compostos heterociclicos
FI943313A0 (fi) Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI894061A0 (fi) Menetelmä lääkeaineina käyttökelpoisten , -disubstituoitujen N-sykloalkyylialkyylibentsyyliamiinien valmistamiseksi ja niiden synteesivälituotteita
DK132188A (da) Anvendelse af tetrahydrobenz(c,d)indol-6-carboxamider som anxiolytika
ATE70274T1 (de) Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide.
DE69015471D1 (de) 1-Benzhydrylazetidine, deren Herstellung und Verwendung als Zwischenprodukte zur Herstellung von Verbindungen mit antimikrobieller Wirkung.
JPS6440449A (en) Substituted 2-nitromethaphenylenediamine, manufacture and hair dye composition
DE59003309D1 (de) Monoklines Metazachlor und Verfahren zu seiner Herstellung.
PT79969B (de) Isoxazol-derivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ZA796789B (en) Novel 3,4-diaza-bicyclo (4.1.0) hept-2-en-5-ones, their preparation, and therapeutic agents containing these compounds
EP0319689A3 (en) N-sultam-sulfon amides substituted by a heterocyclic ring, process for their preparation and their use as herbicides and as plant growth regulators
ATE143573T1 (de) Zahnbürste
ES481207A1 (es) Un procedimiento para l preparacion de derivados de benzoci-cloheptapiridinas.
GR3000725T3 (en) 3-amino-dihydropyridines, process for their preparation and their use as medicaments
DK0483063T3 (da) Ergolinderivater
DE3673797D1 (de) Triazinderivat, seine herstellung und verwendung.
JPS56169612A (en) Hair cosmetic

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee