AR224547A1 - Compuestos de 2-beta-acetoximetil-2-alfa-metil(5r)penam desprovistos de actividad terapeutica,y utiles,como intermediarios para la preparacion de inhibidores de beta-lactamasa,y procedimiento para preparar a dichos inhibidores partiendo del citado intermediario - Google Patents

Compuestos de 2-beta-acetoximetil-2-alfa-metil(5r)penam desprovistos de actividad terapeutica,y utiles,como intermediarios para la preparacion de inhibidores de beta-lactamasa,y procedimiento para preparar a dichos inhibidores partiendo del citado intermediario

Info

Publication number
AR224547A1
AR224547A1 AR282629A AR28262980A AR224547A1 AR 224547 A1 AR224547 A1 AR 224547A1 AR 282629 A AR282629 A AR 282629A AR 28262980 A AR28262980 A AR 28262980A AR 224547 A1 AR224547 A1 AR 224547A1
Authority
AR
Argentina
Prior art keywords
beta
inhidents
inhidated
acetoximetil
penam
Prior art date
Application number
AR282629A
Other languages
English (en)
Spanish (es)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AR224547A1 publication Critical patent/AR224547A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AR282629A 1979-09-26 1980-09-24 Compuestos de 2-beta-acetoximetil-2-alfa-metil(5r)penam desprovistos de actividad terapeutica,y utiles,como intermediarios para la preparacion de inhibidores de beta-lactamasa,y procedimiento para preparar a dichos inhibidores partiendo del citado intermediario AR224547A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/079,127 US4256733A (en) 1979-09-26 1979-09-26 Acetoxymethyl penam compounds as β-lactamase inhibitors

Publications (1)

Publication Number Publication Date
AR224547A1 true AR224547A1 (es) 1981-12-15

Family

ID=22148609

Family Applications (1)

Application Number Title Priority Date Filing Date
AR282629A AR224547A1 (es) 1979-09-26 1980-09-24 Compuestos de 2-beta-acetoximetil-2-alfa-metil(5r)penam desprovistos de actividad terapeutica,y utiles,como intermediarios para la preparacion de inhibidores de beta-lactamasa,y procedimiento para preparar a dichos inhibidores partiendo del citado intermediario

Country Status (36)

Country Link
US (1) US4256733A (xx)
JP (1) JPS6016958B2 (xx)
KR (1) KR840000796B1 (xx)
AR (1) AR224547A1 (xx)
AT (1) AT366384B (xx)
AU (1) AU517074B2 (xx)
BE (1) BE885389A (xx)
CA (1) CA1150242A (xx)
CH (1) CH645646A5 (xx)
CS (1) CS212284B2 (xx)
DD (1) DD153123A5 (xx)
DE (1) DE3035995C2 (xx)
DK (1) DK404980A (xx)
EG (1) EG14888A (xx)
ES (1) ES8106528A1 (xx)
FI (2) FI67552C (xx)
FR (1) FR2465736A1 (xx)
GB (2) GB2059420B (xx)
GR (1) GR70065B (xx)
HU (1) HU183212B (xx)
IE (2) IE50507B1 (xx)
IL (1) IL61117A (xx)
IN (1) IN154557B (xx)
IT (1) IT1132754B (xx)
LU (1) LU82795A1 (xx)
MX (1) MX6580E (xx)
NL (1) NL185923C (xx)
NO (2) NO160370C (xx)
NZ (1) NZ195058A (xx)
PH (1) PH15697A (xx)
PL (1) PL126949B1 (xx)
PT (1) PT71837B (xx)
SE (2) SE449865B (xx)
SU (1) SU959628A3 (xx)
YU (1) YU41733B (xx)
ZA (1) ZA805132B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364957A (en) * 1979-09-26 1982-12-21 Pfizer Inc. Bis-esters of alkanediols as antibacterial agents
US4511512A (en) * 1980-05-01 1985-04-16 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Produktionsaktiensel skab) Substantially pure dicyclohexyl ammonium 6-β-bromo-penicillanate
US4361513A (en) * 1980-12-11 1982-11-30 Pfizer Inc. Esters of penicillanic acid sulfone
US4474698A (en) * 1980-12-11 1984-10-02 Pfizer Inc. Process for preparing esters of penicillanic acid sulfone
US4558042A (en) * 1981-05-06 1985-12-10 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
ZA826687B (en) * 1981-09-14 1983-07-27 Pfizer Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
JPS58185589A (ja) * 1982-04-23 1983-10-29 Taiho Yakuhin Kogyo Kk ペニシリン誘導体
JPS62198687A (ja) * 1986-02-27 1987-09-02 Taiho Yakuhin Kogyo Kk ２β−置換チオメチルペニシリン誘導体
US4861768A (en) * 1986-02-27 1989-08-29 Taiho Pharmaceutical Company, Limited 2 β-substituted thiomethylpenicillin derivatives and their preparation and use
SK63894A3 (en) * 1991-12-19 1995-03-08 Novo Nordisk As Method of preparation of beta-lactam antibiotic
CN115385934A (zh) * 2022-10-26 2022-11-25 北京纳百生物科技有限公司 一种舒巴坦半抗原及其合成方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN149747B (xx) * 1977-06-07 1982-04-03 Pfizer

Also Published As

Publication number Publication date
US4256733A (en) 1981-03-17
MX6580E (es) 1985-07-24
JPS6016958B2 (ja) 1985-04-30
DE3035995A1 (de) 1981-04-02
FI840367A (fi) 1984-01-30
FI67552B (fi) 1984-12-31
YU244980A (en) 1983-02-28
NZ195058A (en) 1982-12-07
IE801095L (en) 1981-01-09
NO160299B (no) 1988-12-27
IL61117A0 (en) 1980-11-30
NO831082L (no) 1981-03-27
PH15697A (en) 1983-03-14
FI840367A0 (fi) 1984-01-30
NO160299C (no) 1989-04-05
AT366384B (de) 1982-04-13
NL185923B (nl) 1990-03-16
NO160370C (no) 1989-04-12
NL185923C (nl) 1990-08-16
AU517074B2 (en) 1981-07-09
YU41733B (en) 1987-12-31
LU82795A1 (fr) 1981-04-17
BE885389A (fr) 1981-03-25
CA1150242A (en) 1983-07-19
GB2125037B (en) 1984-08-01
GB2125037A (en) 1984-02-29
FI67552C (fi) 1985-04-10
GB2059420B (en) 1984-03-14
DE3035995C2 (de) 1985-01-10
IT8024920A0 (it) 1980-09-25
IE50506B1 (en) 1986-04-30
SE449865B (sv) 1987-05-25
JPS5657788A (en) 1981-05-20
CS212284B2 (en) 1982-03-26
DK404980A (da) 1981-03-27
NO802836L (no) 1981-03-27
PT71837B (en) 1981-07-09
GR70065B (xx) 1982-07-26
SE8005714L (sv) 1981-03-27
SE8500965D0 (sv) 1985-02-27
SE461528B (sv) 1990-02-26
DD153123A5 (de) 1981-12-23
KR840000796B1 (ko) 1984-06-12
GB8319784D0 (en) 1983-08-24
AU6271380A (en) 1981-04-09
SU959628A3 (ru) 1982-09-15
ZA805132B (en) 1981-12-30
IE801998L (en) 1981-03-26
ES495354A0 (es) 1981-08-16
FI67854C (fi) 1985-06-10
ATA474680A (de) 1981-08-15
IN154557B (xx) 1984-11-10
GB2059420A (en) 1981-04-23
EG14888A (en) 1985-06-30
PT71837A (en) 1980-10-01
PL126949B1 (en) 1983-09-30
IE50507B1 (en) 1986-04-30
HU183212B (en) 1984-04-28
NO160370B (no) 1989-01-02
IL61117A (en) 1983-10-31
FR2465736B1 (xx) 1982-04-30
KR830003494A (ko) 1983-06-20
NL8005344A (nl) 1981-03-30
FI67854B (fi) 1985-02-28
CH645646A5 (fr) 1984-10-15
FR2465736A1 (fr) 1981-03-27
IT1132754B (it) 1986-07-02
FI803028A (fi) 1981-03-27
PL226868A1 (xx) 1981-10-16
ES8106528A1 (es) 1981-08-16

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