AR117530A2 - Una composición que comprende un virus del síndrome reproductor y respiratorio porcino (prrsv) de un tipo europeo, un producto de vacuna, una composición de proteína, un ácido nucleico aislado y un vector de expresión recombinante - Google Patents
Una composición que comprende un virus del síndrome reproductor y respiratorio porcino (prrsv) de un tipo europeo, un producto de vacuna, una composición de proteína, un ácido nucleico aislado y un vector de expresión recombinanteInfo
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- AR117530A2 AR117530A2 ARP190103882A ARP190103882A AR117530A2 AR 117530 A2 AR117530 A2 AR 117530A2 AR P190103882 A ARP190103882 A AR P190103882A AR P190103882 A ARP190103882 A AR P190103882A AR 117530 A2 AR117530 A2 AR 117530A2
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- seq
- prrsv
- nucleic acid
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
- C12N2770/10064—Methods of inactivation or attenuation by serial passage
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10071—Demonstrated in vivo effect
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
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- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Reivindicación 1: Una composición, caracterizada porque comprende un virus del síndrome reproductor y respiratorio porcino (PRRSV) de un tipo europeo, que es de la cepa depositada en la Colección europea de cultivos celulares (ECACC) con el número de acceso ECACC 11012502. Reivindicación 5: La composición según cualquiera de las reivindicaciones 1 a 4, caracterizada porque además comprende uno o más patógenos atenuados o inactivados no PRRSV o material antigénico del mismo. Reivindicación 6: La composición según la reivindicación 5, caracterizada porque dichos patógenos no PRRSV se seleccionan de virus de la seudorrabia, virus de la gripe porcina, parvovirus porcino, virus de la gastroenteritis transmisible, Escherichia coli, Erysipelas rhusiopathiae, Bordetella bronchiseptica, Salmonella choleraesuis, Haemophilus parasuis, Pasteurella multocida, Streptococcus suis, Mycoplasma hyopneumoniae y Actinobacillus pleuropneumoniae. Reivindicación 13: Un producto de vacuna, caracterizado porque comprende en recipientes separados una composición liofilizada de acuerdo con cualquiera de las reivindicaciones 1 a 7, y un disolvente para reconstitución, y que opcionalmente contiene adicionalmente un prospecto o etiqueta que comprende instrucciones de uso. Reivindicación 15: Una composición de proteína que comprende una proteína que tiene la secuencia de SEQ ID Nº 7, o las proteínas que tienen las secuencias de SEQ ID Nº 2; SEQ ID Nº 3; SEQ ID Nº 4; SEQ ID Nº 5; SEQ ID Nº 6; SEQ ID Nº 7; SEQ ID Nº 8 y SEQ ID Nº 9. Reivindicación 18: El vector de expresión recombinante según la reivindicación 17, caracterizado porque (i) dicha secuencia de ácido nucleico que codifica dicho ORF es SEQ ID Nº 24, o (ii) dicha secuencia de ácido nucleico que codifica dichos ORFs comprende SEQ ID Nº 19; SEQ ID Nº 20, SEQ ID Nº 21; SEQ ID Nº 22; SEQ ID Nº 23; SEQ ID Nº 24; SEQ ID Nº 25 y SEQ ID Nº 26.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161444074P | 2011-02-17 | 2011-02-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR117530A2 true AR117530A2 (es) | 2021-08-11 |
Family
ID=45614840
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120100538A Pending AR085272A1 (es) | 2011-02-17 | 2012-02-16 | Cepa del prrsv (virus del sindrome reproductor y respiratorio porcino) europea |
ARP190103882A AR117530A2 (es) | 2011-02-17 | 2019-12-30 | Una composición que comprende un virus del síndrome reproductor y respiratorio porcino (prrsv) de un tipo europeo, un producto de vacuna, una composición de proteína, un ácido nucleico aislado y un vector de expresión recombinante |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120100538A Pending AR085272A1 (es) | 2011-02-17 | 2012-02-16 | Cepa del prrsv (virus del sindrome reproductor y respiratorio porcino) europea |
Country Status (30)
Country | Link |
---|---|
US (4) | US8765142B2 (es) |
EP (2) | EP2959916B1 (es) |
JP (1) | JP5788027B2 (es) |
KR (2) | KR102073075B1 (es) |
CN (2) | CN103370078B (es) |
AR (2) | AR085272A1 (es) |
AU (2) | AU2012217169B2 (es) |
BR (2) | BR112013021076B1 (es) |
CA (1) | CA2826341C (es) |
CL (1) | CL2013002379A1 (es) |
CO (1) | CO6791570A2 (es) |
CY (1) | CY1116835T1 (es) |
DK (2) | DK2959916T3 (es) |
EA (2) | EA035624B1 (es) |
ES (2) | ES2550258T3 (es) |
HR (1) | HRP20151031T1 (es) |
HU (1) | HUE027731T2 (es) |
ME (1) | ME02271B (es) |
MX (2) | MX345188B (es) |
MY (2) | MY161198A (es) |
PH (1) | PH12017500962A1 (es) |
PL (2) | PL2675475T3 (es) |
PT (2) | PT2959916T (es) |
RS (1) | RS54231B1 (es) |
SG (1) | SG192820A1 (es) |
SI (1) | SI2675475T1 (es) |
SM (1) | SMT201500236B (es) |
TW (2) | TWI665303B (es) |
UA (2) | UA117272C2 (es) |
WO (1) | WO2012110489A2 (es) |
Families Citing this family (26)
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DK2959916T3 (en) | 2011-02-17 | 2018-10-29 | Boehringer Ingelheim Vetmedica Gmbh | New European PRRSV strain. |
CA2827337C (en) | 2011-02-17 | 2019-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
US8906385B2 (en) | 2011-12-01 | 2014-12-09 | University Of Maryland, College Park | Interferon-inducing porcine reproductive and respiratory syndrome virus isolate |
JP6386999B2 (ja) | 2012-05-17 | 2018-09-05 | ゾエティス・エルエルシー | ブタ生殖および呼吸症候群(prrs)ウイルスに対する離乳前の効果的なワクチン接種 |
US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
US9457073B2 (en) | 2012-09-26 | 2016-10-04 | University Of Manitoba | Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity |
CN105308178B (zh) * | 2012-12-07 | 2019-06-07 | 伊利诺伊大学评议会 | 猪繁殖与呼吸综合征病毒组合物及其用途 |
US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
HUE061768T2 (hu) * | 2013-12-20 | 2023-08-28 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus variáns, európai PRRS virus cDNS klón, és alkalmazásuk |
US10280199B2 (en) | 2014-02-07 | 2019-05-07 | Phibro Animal Health Corporation | Coronavirus proteins and antigens |
AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
TWI670085B (zh) * | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
US11040059B2 (en) | 2014-10-27 | 2021-06-22 | Pharmacosmos Holding A/S | Treatment or prevention of anaemia in pregnant non-human mammals |
CN106924726B (zh) * | 2015-12-29 | 2021-02-09 | 普莱柯生物工程股份有限公司 | 一种用于预防猪繁殖与呼吸综合征的疫苗组合物及其制备方法和应用 |
US10279031B2 (en) | 2016-05-11 | 2019-05-07 | Phibro Animal Health Corporation | Composition comprising antigens and a mucosal adjuvant and a method for using |
WO2017196318A1 (en) * | 2016-05-11 | 2017-11-16 | Phibro Animal Health Corporation | A composition comprising antigens and a mucosal adjuvant and a method for using |
PT3534939T (pt) | 2016-11-03 | 2023-04-20 | Boehringer Ingelheim Vetmedica Gmbh | Vacina contra parvovírus porcino e vírus da síndrome reprodutiva e respiratória porcina e métodos da sua produção |
CA3047294A1 (en) * | 2016-12-14 | 2018-06-21 | Zoetis Services Llc | Effective vaccination against european strains of porcine reproductive and respiratory syndrome (prrs) virus prior to weaning |
US11013796B2 (en) | 2018-08-30 | 2021-05-25 | Iowa State University Research Foundation, Inc. | Porcine parainfluenza virus type 1 isolates and immunogenic compositions therefrom |
CN114222579A (zh) | 2019-04-04 | 2022-03-22 | 勃林格殷格翰动物保健美国有限公司 | 猪圆环病毒3型(pcv3)疫苗及其生产和用途 |
CN110735005B (zh) * | 2019-11-26 | 2023-01-10 | 广西大学 | Siv和prrsv多重rt-pcr快速检测试剂盒及引物 |
CN111676247A (zh) * | 2020-06-30 | 2020-09-18 | 扬州大学 | 一株猪繁殖与呼吸综合征病毒1型分离株感染性克隆构建、拯救与应用 |
MX2023001024A (es) | 2020-07-24 | 2023-02-15 | Boehringer Ingelheim Animal Health Usa Inc | Vacuna porcina combinada. |
CN113862230B (zh) * | 2021-09-30 | 2023-08-08 | 中牧实业股份有限公司 | 一种猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
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