AR108130A1 - Derivados de pirazolopirimidina - Google Patents

Derivados de pirazolopirimidina

Info

Publication number
AR108130A1
AR108130A1 ARP170100939A ARP170100939A AR108130A1 AR 108130 A1 AR108130 A1 AR 108130A1 AR P170100939 A ARP170100939 A AR P170100939A AR P170100939 A ARP170100939 A AR P170100939A AR 108130 A1 AR108130 A1 AR 108130A1
Authority
AR
Argentina
Prior art keywords
alkyl
halogen atoms
halogenoalkyl
group
cycloalkyl
Prior art date
Application number
ARP170100939A
Other languages
English (en)
Spanish (es)
Inventor
Claudia Bhm
Adamczewski Martin Dr
Raming Klaus Dr
Nennstiel Dirk Dr
Hink Maike Dr
Ebbinghaus-Kintscher Ulrich Dr
Ulrich Grgens
Schwarz Hans Dr
- Dr Hbsch Walter Georg
Kbberling Johannes Dr
Dr Ilg Thomas Prof
Kulke Daniel Dr
Brngen Kirsten Dr
Welz Claudia Dr
Khler Adeline Dr
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of AR108130A1 publication Critical patent/AR108130A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
ARP170100939A 2016-04-15 2017-04-12 Derivados de pirazolopirimidina AR108130A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16165572 2016-04-15

Publications (1)

Publication Number Publication Date
AR108130A1 true AR108130A1 (es) 2018-07-18

Family

ID=55755480

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170100939A AR108130A1 (es) 2016-04-15 2017-04-12 Derivados de pirazolopirimidina

Country Status (22)

Country Link
US (3) US10604525B2 (https=)
EP (1) EP3442974B8 (https=)
JP (1) JP7051703B2 (https=)
KR (1) KR102467347B1 (https=)
CN (1) CN109071545B (https=)
AR (1) AR108130A1 (https=)
AU (1) AU2017251155B2 (https=)
CA (1) CA3020793C (https=)
CL (1) CL2018002920A1 (https=)
CO (1) CO2018010966A2 (https=)
DO (1) DOP2018000226A (https=)
ES (1) ES2953467T3 (https=)
IL (1) IL261885A (https=)
MX (1) MX389697B (https=)
PH (1) PH12018550173A1 (https=)
PL (1) PL3442974T3 (https=)
RU (1) RU2769448C2 (https=)
SG (1) SG11201808214TA (https=)
TW (1) TWI742067B (https=)
UY (1) UY37201A (https=)
WO (1) WO2017178416A1 (https=)
ZA (1) ZA201807656B (https=)

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WO2019118928A1 (en) 2017-12-15 2019-06-20 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
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EP3643711A1 (en) 2018-10-24 2020-04-29 Bayer Animal Health GmbH New anthelmintic compounds
NZ777370A (en) 2018-12-18 2024-11-29 Elanco Tiergesundheit Ag Bicyclic derivatives
CN113490527B (zh) * 2018-12-18 2024-10-25 瑞士伊兰科动物保健有限公司 双环衍生物
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
US12502377B2 (en) 2019-04-04 2025-12-23 Tarsus Pharmaceuticals, Inc. Method of eradicating ticks that attach to humans using lotilaner formulations
BR112021024726A2 (pt) * 2019-06-07 2022-01-18 Elanco Tiergesundheit Ag Novos derivados bicíclicos
TWI865563B (zh) 2019-07-30 2024-12-11 德商拜耳動物保健有限公司 新穎異喹啉衍生物
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AU2020406093A1 (en) * 2019-12-18 2022-06-16 Intervet International B.V. Anthelmintic compounds comprising a quinoline structure
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
CN116685584A (zh) * 2020-11-18 2023-09-01 礼蓝动物保健有限公司 用于治疗心丝虫感染的n-(2,3-二氢-1,4-苯并噁嗪-4-基)-3-异丙基-7-(2,3,5-三氟苯基)苯并噻吩-2-甲酰胺衍生物和类似化合物
WO2022106469A2 (en) 2020-11-18 2022-05-27 Elanco Tiergesundheit Ag N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections
TW202237600A (zh) 2020-12-04 2022-10-01 瑞士商禮藍動物保健股份有限公司 雙環衍生物
US20240043446A1 (en) 2020-12-11 2024-02-08 Intervet Inc. Anthelmintic compounds comprising a thienopyridine structure
CN113252824B (zh) * 2021-06-17 2022-04-19 湖南农业大学 测定水体中三氟苯嘧啶含量的气相色谱-电子捕获检测器法
KR102660894B1 (ko) * 2021-09-17 2024-04-26 기초과학연구원 피리미딘-2-아민 화합물의 제조방법
UY39995A (es) 2021-11-01 2023-05-15 Boehringer Ingelheim Vetmedica GmbH Compuestos de pirrolopiridazina como antihelmínticos
WO2024213752A1 (en) 2023-04-14 2024-10-17 Elanco Animal Health Gmbh Long-term prevention and/or treatment of a disease by slo-1 inhibitors
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CN119139315B (zh) * 2024-09-23 2026-03-10 大连大学 D724-0491在制备治疗乳腺癌药物中的应用
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Also Published As

Publication number Publication date
CL2018002920A1 (es) 2019-02-01
ES2953467T3 (es) 2023-11-13
WO2017178416A1 (en) 2017-10-19
EP3442974B8 (en) 2023-07-12
US20200239482A1 (en) 2020-07-30
CN109071545A (zh) 2018-12-21
MX2018012544A (es) 2019-01-31
US20190071447A1 (en) 2019-03-07
KR102467347B1 (ko) 2022-11-14
TW201803874A (zh) 2018-02-01
MX389697B (es) 2025-03-20
US20200299299A1 (en) 2020-09-24
CA3020793A1 (en) 2017-10-19
US11001590B2 (en) 2021-05-11
JP7051703B2 (ja) 2022-04-11
UY37201A (es) 2017-11-30
EP3442974C0 (en) 2023-06-07
US10934301B2 (en) 2021-03-02
DOP2018000226A (es) 2018-11-15
RU2018140092A3 (https=) 2020-06-25
NZ747056A (en) 2025-05-30
CA3020793C (en) 2024-05-21
AU2017251155B2 (en) 2021-08-05
RU2018140092A (ru) 2020-05-15
CO2018010966A2 (es) 2018-10-22
CN109071545B (zh) 2021-08-03
KR20180134966A (ko) 2018-12-19
EP3442974B1 (en) 2023-06-07
TWI742067B (zh) 2021-10-11
IL261885A (en) 2018-10-31
PL3442974T3 (pl) 2023-12-04
PH12018550173A1 (en) 2019-07-15
EP3442974A1 (en) 2019-02-20
US10604525B2 (en) 2020-03-31
JP2019513776A (ja) 2019-05-30
SG11201808214TA (en) 2018-10-30
RU2769448C2 (ru) 2022-03-31
AU2017251155A1 (en) 2018-10-11
ZA201807656B (en) 2024-06-26

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