SG11202002218VA - Pyrazolopyrimidinone compounds and uses thereof - Google Patents
Pyrazolopyrimidinone compounds and uses thereofInfo
- Publication number
- SG11202002218VA SG11202002218VA SG11202002218VA SG11202002218VA SG11202002218VA SG 11202002218V A SG11202002218V A SG 11202002218VA SG 11202002218V A SG11202002218V A SG 11202002218VA SG 11202002218V A SG11202002218V A SG 11202002218VA SG 11202002218V A SG11202002218V A SG 11202002218VA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrazolopyrimidinone compounds
- pyrazolopyrimidinone
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762559482P | 2017-09-15 | 2017-09-15 | |
| US201862633248P | 2018-02-21 | 2018-02-21 | |
| US201862687769P | 2018-06-20 | 2018-06-20 | |
| PCT/US2018/051014 WO2019055750A1 (en) | 2017-09-15 | 2018-09-14 | Pyrazolopyrimidinone compounds and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202002218VA true SG11202002218VA (en) | 2020-04-29 |
Family
ID=65723108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202002218VA SG11202002218VA (en) | 2017-09-15 | 2018-09-14 | Pyrazolopyrimidinone compounds and uses thereof |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10738056B2 (en) |
| EP (1) | EP3681888A4 (en) |
| JP (1) | JP2020533376A (en) |
| KR (1) | KR20200032751A (en) |
| CN (1) | CN111212839A (en) |
| AU (1) | AU2018331456B2 (en) |
| BR (1) | BR112020003676A2 (en) |
| CA (1) | CA3075751A1 (en) |
| CL (1) | CL2020000544A1 (en) |
| CO (1) | CO2020002107A2 (en) |
| CR (1) | CR20200114A (en) |
| DO (1) | DOP2020000051A (en) |
| EC (1) | ECSP20018586A (en) |
| IL (1) | IL273236A (en) |
| JO (1) | JOP20200055A1 (en) |
| MA (1) | MA50256A (en) |
| MX (1) | MX2020002869A (en) |
| PE (1) | PE20210340A1 (en) |
| PH (1) | PH12020500500A1 (en) |
| SG (1) | SG11202002218VA (en) |
| TW (1) | TW201920185A (en) |
| WO (1) | WO2019055750A1 (en) |
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| CA3034705C (en) | 2016-08-31 | 2021-08-03 | Agios Pharmaceuticals, Inc. | Inhibitors of cellular metabolic processes |
| JOP20170192A1 (en) | 2016-12-01 | 2019-01-30 | Takeda Pharmaceuticals Co | Cyclic dinucleotide |
| MX2020004858A (en) | 2017-11-10 | 2020-10-01 | Takeda Pharmaceuticals Co | Sting modulator compounds, and methods of making and using. |
| AU2018392212B9 (en) | 2017-12-20 | 2021-03-18 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein |
| KR102492187B1 (en) | 2017-12-20 | 2023-01-27 | 인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. | 3'3' cyclic dinucleotides with phosphonate linkages that activate STING adapter proteins |
| TWI818007B (en) | 2018-04-06 | 2023-10-11 | 捷克科學院有機化學與生物化學研究所 | 2'3'-cyclic dinucleotides |
| KR20200140867A (en) | 2018-04-06 | 2020-12-16 | 인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. | 3'3'-cyclic dinucleotide |
| MA55805A (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | METHODS OF MODULATING IMMUNE ACTIVITY |
| MX2022002152A (en) * | 2019-08-21 | 2022-05-18 | Scripps Research Inst | Bicyclic agonists of stimulator of interferon genes sting. |
| CN110724143B (en) * | 2019-10-09 | 2021-03-23 | 清华大学 | Preparation of target BTK protein degradation compound and application of target BTK protein degradation compound in treatment of autoimmune system diseases and tumors |
| CN110627725B (en) * | 2019-10-14 | 2022-10-18 | 遵义医科大学 | 4-substituted 5-difluoromethyl-3-nitro-1H-pyrazole compound and preparation method and application thereof |
| IL293191A (en) | 2019-11-25 | 2022-07-01 | Amgen Inc | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use |
| CN113248491B (en) * | 2020-02-11 | 2022-02-25 | 中国科学院上海药物研究所 | Substituted indole urea derivatives, synthesis method and application thereof |
| EP4153593A1 (en) * | 2020-05-20 | 2023-03-29 | F. Hoffmann-La Roche AG | Cgas inhibiting triazolopyrimidone derivatives |
| JP2023527698A (en) * | 2020-05-20 | 2023-06-30 | エフ． ホフマン－ラ ロシュ アーゲー | Novel malonitrile derivative |
| WO2021233851A1 (en) * | 2020-05-20 | 2021-11-25 | F. Hoffmann-La Roche Ag | New malonitrile derivatives |
| PE20231947A1 (en) | 2020-11-09 | 2023-12-05 | Takeda Pharmaceuticals Co | ANTIBODY AND DRUG CONJUGATES |
| CN114644633A (en) * | 2020-12-18 | 2022-06-21 | 北京诺诚健华医药科技有限公司 | Heterocyclic JAK inhibitors |
| EP4267571A1 (en) * | 2020-12-22 | 2023-11-01 | Novartis AG | Pyrrolo[3,2-b]pyridine derivatives useful in treating conditions associated with cgas |
| WO2022221188A1 (en) * | 2021-04-13 | 2022-10-20 | University Of Washington | Designed constitutively active cyclic gmp-amp synthase as a genetically encoded stimulant of interferons |
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| WO2018039972A1 (en) | 2016-08-31 | 2018-03-08 | Agios Pharmaceuticals, Inc. | Inhibitors of cellular metabolic processes |
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-
2018
- 2018-09-14 CR CR20200114A patent/CR20200114A/en unknown
- 2018-09-14 KR KR1020207007178A patent/KR20200032751A/en not_active Application Discontinuation
- 2018-09-14 BR BR112020003676-5A patent/BR112020003676A2/en not_active Application Discontinuation
- 2018-09-14 CA CA3075751A patent/CA3075751A1/en not_active Abandoned
- 2018-09-14 TW TW107132537A patent/TW201920185A/en unknown
- 2018-09-14 AU AU2018331456A patent/AU2018331456B2/en not_active Ceased
- 2018-09-14 MX MX2020002869A patent/MX2020002869A/en unknown
- 2018-09-14 EP EP18857356.2A patent/EP3681888A4/en not_active Withdrawn
- 2018-09-14 JO JOP/2020/0055A patent/JOP20200055A1/en unknown
- 2018-09-14 MA MA050256A patent/MA50256A/en unknown
- 2018-09-14 CN CN201880059704.2A patent/CN111212839A/en active Pending
- 2018-09-14 US US16/131,221 patent/US10738056B2/en active Active
- 2018-09-14 WO PCT/US2018/051014 patent/WO2019055750A1/en unknown
- 2018-09-14 SG SG11202002218VA patent/SG11202002218VA/en unknown
- 2018-09-14 JP JP2020515108A patent/JP2020533376A/en not_active Withdrawn
- 2018-09-14 PE PE2020000341A patent/PE20210340A1/en unknown
-
2020
- 2020-02-27 CO CONC2020/0002107A patent/CO2020002107A2/en unknown
- 2020-03-02 DO DO2020000051A patent/DOP2020000051A/en unknown
- 2020-03-04 CL CL2020000544A patent/CL2020000544A1/en unknown
- 2020-03-11 IL IL273236A patent/IL273236A/en unknown
- 2020-03-12 PH PH12020500500A patent/PH12020500500A1/en unknown
- 2020-03-13 EC ECSENADI202018586A patent/ECSP20018586A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200032751A (en) | 2020-03-26 |
| CR20200114A (en) | 2020-06-01 |
| PH12020500500A1 (en) | 2021-03-01 |
| EP3681888A1 (en) | 2020-07-22 |
| MA50256A (en) | 2020-07-22 |
| US20190119285A1 (en) | 2019-04-25 |
| US10738056B2 (en) | 2020-08-11 |
| DOP2020000051A (en) | 2020-08-15 |
| CO2020002107A2 (en) | 2020-05-29 |
| IL273236A (en) | 2020-04-30 |
| WO2019055750A1 (en) | 2019-03-21 |
| EP3681888A4 (en) | 2021-07-07 |
| AU2018331456B2 (en) | 2020-10-08 |
| BR112020003676A2 (en) | 2020-09-01 |
| JOP20200055A1 (en) | 2020-03-10 |
| CA3075751A1 (en) | 2019-03-21 |
| CL2020000544A1 (en) | 2020-10-02 |
| ECSP20018586A (en) | 2020-06-30 |
| MX2020002869A (en) | 2020-07-24 |
| TW201920185A (en) | 2019-06-01 |
| JP2020533376A (en) | 2020-11-19 |
| PE20210340A1 (en) | 2021-02-22 |
| AU2018331456A1 (en) | 2020-03-05 |
| CN111212839A (en) | 2020-05-29 |
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