AR068086A2 - Polimorfos del compuesto triazolo (4,5-d) pirimidina , una mezcla , proceso para su preparacion , composicion farmaceutica y uso de estos compuestos para la fabricacion de medicamentos - Google Patents

Polimorfos del compuesto triazolo (4,5-d) pirimidina , una mezcla , proceso para su preparacion , composicion farmaceutica y uso de estos compuestos para la fabricacion de medicamentos

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Publication number
AR068086A2
AR068086A2 ARP080103205A ARP080103205A AR068086A2 AR 068086 A2 AR068086 A2 AR 068086A2 AR P080103205 A ARP080103205 A AR P080103205A AR P080103205 A ARP080103205 A AR P080103205A AR 068086 A2 AR068086 A2 AR 068086A2
Authority
AR
Argentina
Prior art keywords
compound
medicines
compounds
manufacture
mixture
Prior art date
Application number
ARP080103205A
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English (en)
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Astrazeneca Ab
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9892841&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR068086(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR068086A2 publication Critical patent/AR068086A2/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un compuesto que tiene la formula (1), en una forma sustancialmente cristalina; una mezcla, proceso para su preparacion, composicion farmacéutica, y uso de estos compuestos para la fabricacion de medicamentos, utiles para prevenir complicaciones tromboticas. Reivindicacion 4: Un compuesto de la formula (1) como se reivindica en la reivindicacion 1 o 3 caracterizado un patron de difraccion del polvo por rayos X que contiene picos específicos a 5,3° (+- 0,1°), 8,0° (+- 0,1°), 9,6° (+- 0,1°), 13,9° (+- 0,1°), 15,3° (+- 0,1°) 20 1° (+- 01°) 20,7° (+ -01°) 21,0° (+ -0 1°) 21,3° (+ -0 1°), 26,2° (+ -0 1°) y 27,5° (+- 0,1°) 2theta. Reivindicacion 7: Un compuesto de la formula (1) como se reivindica en la reivindicacion 1 o 6, caracterizado por un patron de difraccion de polvo por rayos X que contiene picos específicos a 5,5° (+- 0,1°), 6,8° (+- 0,1°), 10,6° (+- 0,1°), 13,5° (+- 0,1°), 14,9° (+- 0,1°), 18,3° (+- 0,1°), 19,2° (+- 0,1°), 22,7° (+- 0,1°), 24,3° (+- 0,1°) y 27,1° (+- 0,1°) 2theta. Reivindicacion 10: Un compuesto de la formula (1) como se reivindica en las reivindicaciones 1 o 9, caracterizado por un patron de difraccion de polvo por rayos X que contiene picos específicos a 5,6° (+- 0,1°), 12,5° (+- 0,1°), 14,0° (+- 0 1°) 17,4° (+ -0 1°), 18,4° (+ -0,1°), 21,4° (+- 0,1°), 22,2° (+- 0,1°), 22,9° (+ -0,1°), 24,1° (+- 0,1°) y 24,5° (+- 0,1°) 2theta. Reivindicacion 13: Un compuesto de la formula (1) como se reivindica en la reivindicacion 1 o 12 caracterizado por un patron de difraccion de polvo por rayos X que contiene picos específicos a 4,9° (+- 0,1°), 6,0° (+- 0,1°), 9,2° (+- 0,1°), 11,6° (+- 0,1°), 12,8° (+- 0,1°), 15,6° (+- 0,1°), 16,4° (+- 0,1°), 17,2° (+- 0,1°), y 18,1° (+- 0,1°) 2theta.
ARP080103205A 2000-06-02 2008-07-24 Polimorfos del compuesto triazolo (4,5-d) pirimidina , una mezcla , proceso para su preparacion , composicion farmaceutica y uso de estos compuestos para la fabricacion de medicamentos AR068086A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0013407.2A GB0013407D0 (en) 2000-06-02 2000-06-02 Forms of a chemical compound

Publications (1)

Publication Number Publication Date
AR068086A2 true AR068086A2 (es) 2009-11-04

Family

ID=9892841

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010102432A AR032335A1 (es) 2000-06-02 2001-05-22 Polimorfos del compuesto triazolo [4,5-d] pirimidina, una mezcla, proceso para su preparacion, composicion farmaceutica, y uso de estos compuestos para la fabricacion de medicamentos
ARP080103205A AR068086A2 (es) 2000-06-02 2008-07-24 Polimorfos del compuesto triazolo (4,5-d) pirimidina , una mezcla , proceso para su preparacion , composicion farmaceutica y uso de estos compuestos para la fabricacion de medicamentos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP010102432A AR032335A1 (es) 2000-06-02 2001-05-22 Polimorfos del compuesto triazolo [4,5-d] pirimidina, una mezcla, proceso para su preparacion, composicion farmaceutica, y uso de estos compuestos para la fabricacion de medicamentos

Country Status (36)

Country Link
US (3) US20030181469A1 (es)
EP (3) EP2292622A1 (es)
JP (3) JP5036947B2 (es)
KR (1) KR100781864B1 (es)
CN (2) CN1817883B (es)
AR (2) AR032335A1 (es)
AT (2) ATE555115T1 (es)
AU (4) AU6287401A (es)
BG (3) BG65837B1 (es)
BR (1) BR0111328A (es)
CA (1) CA2408596C (es)
CY (1) CY1113047T1 (es)
CZ (2) CZ307468B6 (es)
DE (1) DE60117972T2 (es)
DK (2) DK1493745T3 (es)
EE (1) EE05222B1 (es)
ES (2) ES2384708T3 (es)
GB (1) GB0013407D0 (es)
HK (2) HK1052347B (es)
HU (2) HU229374B1 (es)
IL (4) IL152777A0 (es)
IS (2) IS2609B (es)
MX (1) MXPA02011795A (es)
MY (2) MY140674A (es)
NO (3) NO323780B1 (es)
NZ (1) NZ522638A (es)
PH (1) PH12011000127A1 (es)
PL (2) PL359172A1 (es)
PT (2) PT1493745E (es)
RU (3) RU2325391C2 (es)
SG (1) SG135965A1 (es)
SI (2) SI1289992T1 (es)
SK (1) SK287817B6 (es)
UA (1) UA73181C2 (es)
WO (1) WO2001092262A1 (es)
ZA (1) ZA200209324B (es)

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