AR059964A1 - Metodos para reducir la aglomeracion de proteina - Google Patents
Metodos para reducir la aglomeracion de proteinaInfo
- Publication number
- AR059964A1 AR059964A1 ARP070101104A ARP070101104A AR059964A1 AR 059964 A1 AR059964 A1 AR 059964A1 AR P070101104 A ARP070101104 A AR P070101104A AR P070101104 A ARP070101104 A AR P070101104A AR 059964 A1 AR059964 A1 AR 059964A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- protein
- aglomeration
- reduce protein
- formulations
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invencion se refiere a métodos para reducir la aglomeracion de una proteína o proteínas en una formulacion y formulaciones de proteínas que tienen propiedades de aglomeracion reducidas. Los métodos y formulaciones descritas en este documento, mantienen la actividad biologica de una proteína e incrementan la vida de anaquel de las formulaciones de proteína.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78413006P | 2006-03-20 | 2006-03-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR059964A1 true AR059964A1 (es) | 2008-05-14 |
Family
ID=38523027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070101104A AR059964A1 (es) | 2006-03-20 | 2007-03-19 | Metodos para reducir la aglomeracion de proteina |
Country Status (18)
Country | Link |
---|---|
US (1) | US20080064856A1 (es) |
EP (1) | EP1996221A2 (es) |
JP (1) | JP2009530380A (es) |
KR (1) | KR20080108554A (es) |
CN (1) | CN101420972A (es) |
AR (1) | AR059964A1 (es) |
AU (1) | AU2007227408A1 (es) |
BR (1) | BRPI0709059A2 (es) |
CA (1) | CA2646934C (es) |
CR (1) | CR10290A (es) |
EC (1) | ECSP088758A (es) |
IL (1) | IL194123A0 (es) |
MX (1) | MX2008011888A (es) |
NO (1) | NO20083940L (es) |
PE (1) | PE20080121A1 (es) |
RU (1) | RU2008137634A (es) |
TW (1) | TW200806317A (es) |
WO (1) | WO2007109221A2 (es) |
Families Citing this family (94)
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CN106822891A (zh) | 2008-06-20 | 2017-06-13 | 诺华公司 | 具有降低的聚集的免疫球蛋白 |
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KR101852328B1 (ko) * | 2009-07-06 | 2018-04-26 | 사노피-아벤티스 도이칠란트 게엠베하 | 메티오닌을 함유하는 수성 인슐린 제제 |
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CN116322920A (zh) | 2020-11-09 | 2023-06-23 | 武田药品工业株式会社 | 使用氧化硅吸附从血浆中纯化fviii |
WO2024058201A1 (ja) * | 2022-09-16 | 2024-03-21 | 国立研究開発法人量子科学技術研究開発機構 | 放射性医薬組成物の中間体の製造方法、放射性医薬組成物の中間体の精製用キット |
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US20030104996A1 (en) * | 2001-08-30 | 2003-06-05 | Tiansheng Li | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
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ES2321297T3 (es) * | 2003-01-08 | 2009-06-04 | Novartis Vaccines And Diagnostics, Inc. | Composiciones acuosas estabilizadas que comprenden inhibidor de la via del factor tisular (ivft) o variante del inhibidor de la via del factor tisular. |
BRPI0418115A (pt) * | 2003-12-23 | 2007-04-17 | Pharmacia Corp | formulação lìquida estável de hormÈnio de crescimento |
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RU2007124933A (ru) * | 2005-01-28 | 2009-03-10 | Вайет (Us) | Стабилизированные жидкие полипептидные составы |
-
2007
- 2007-03-08 TW TW096108014A patent/TW200806317A/zh unknown
- 2007-03-16 PE PE2007000286A patent/PE20080121A1/es not_active Application Discontinuation
- 2007-03-19 BR BRPI0709059-5A patent/BRPI0709059A2/pt not_active IP Right Cessation
- 2007-03-19 KR KR1020087025501A patent/KR20080108554A/ko not_active Application Discontinuation
- 2007-03-19 AU AU2007227408A patent/AU2007227408A1/en not_active Abandoned
- 2007-03-19 US US11/725,534 patent/US20080064856A1/en not_active Abandoned
- 2007-03-19 MX MX2008011888A patent/MX2008011888A/es not_active Application Discontinuation
- 2007-03-19 CA CA2646934A patent/CA2646934C/en not_active Expired - Fee Related
- 2007-03-19 EP EP07753416A patent/EP1996221A2/en not_active Ceased
- 2007-03-19 AR ARP070101104A patent/AR059964A1/es unknown
- 2007-03-19 RU RU2008137634/15A patent/RU2008137634A/ru not_active Application Discontinuation
- 2007-03-19 JP JP2009501487A patent/JP2009530380A/ja active Pending
- 2007-03-19 CN CNA2007800132437A patent/CN101420972A/zh active Pending
- 2007-03-19 WO PCT/US2007/006787 patent/WO2007109221A2/en active Application Filing
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2008
- 2008-09-16 NO NO20083940A patent/NO20083940L/no unknown
- 2008-09-16 IL IL194123A patent/IL194123A0/en unknown
- 2008-09-16 CR CR10290A patent/CR10290A/es not_active Application Discontinuation
- 2008-09-22 EC EC2008008758A patent/ECSP088758A/es unknown
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MX2008011888A (es) | 2008-09-29 |
WO2007109221A2 (en) | 2007-09-27 |
CN101420972A (zh) | 2009-04-29 |
CA2646934A1 (en) | 2007-09-27 |
JP2009530380A (ja) | 2009-08-27 |
NO20083940L (no) | 2008-10-16 |
BRPI0709059A2 (pt) | 2011-06-21 |
CR10290A (es) | 2008-11-26 |
ECSP088758A (es) | 2008-10-31 |
US20080064856A1 (en) | 2008-03-13 |
WO2007109221A3 (en) | 2008-02-21 |
WO2007109221A9 (en) | 2007-12-06 |
KR20080108554A (ko) | 2008-12-15 |
IL194123A0 (en) | 2011-08-01 |
AU2007227408A1 (en) | 2007-09-27 |
EP1996221A2 (en) | 2008-12-03 |
PE20080121A1 (es) | 2008-03-05 |
RU2008137634A (ru) | 2010-04-27 |
CA2646934C (en) | 2014-09-23 |
TW200806317A (en) | 2008-02-01 |
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