ATE543506T1 - Methode zur stabilisierung von proteinen - Google Patents

Methode zur stabilisierung von proteinen

Info

Publication number
ATE543506T1
ATE543506T1 AT05749282T AT05749282T ATE543506T1 AT E543506 T1 ATE543506 T1 AT E543506T1 AT 05749282 T AT05749282 T AT 05749282T AT 05749282 T AT05749282 T AT 05749282T AT E543506 T1 ATE543506 T1 AT E543506T1
Authority
AT
Austria
Prior art keywords
bulk
monomeric protein
excipient
stabilizing proteins
agents
Prior art date
Application number
AT05749282T
Other languages
English (en)
Inventor
Amer Jaber
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of ATE543506T1 publication Critical patent/ATE543506T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05749282T 2004-06-01 2005-05-27 Methode zur stabilisierung von proteinen ATE543506T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04076627 2004-06-01
PCT/EP2005/052413 WO2005117948A1 (en) 2004-06-01 2005-05-27 Method of stabilizing proteins

Publications (1)

Publication Number Publication Date
ATE543506T1 true ATE543506T1 (de) 2012-02-15

Family

ID=34928262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749282T ATE543506T1 (de) 2004-06-01 2005-05-27 Methode zur stabilisierung von proteinen

Country Status (17)

Country Link
US (1) US7858082B2 (de)
EP (1) EP1750750B1 (de)
JP (1) JP2008500995A (de)
CN (1) CN1993138B (de)
AT (1) ATE543506T1 (de)
AU (1) AU2005249232B2 (de)
BR (1) BRPI0510527A (de)
CA (1) CA2567309A1 (de)
EA (1) EA012281B1 (de)
ES (1) ES2381674T3 (de)
HK (1) HK1102561A1 (de)
IL (1) IL179617A0 (de)
MX (1) MXPA06014079A (de)
NO (1) NO20065861L (de)
UA (1) UA93349C2 (de)
WO (1) WO2005117948A1 (de)
ZA (1) ZA200610041B (de)

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AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
BR112012011403B8 (pt) 2009-11-13 2021-05-25 Sanofi Aventis Deutschland composição farmacêutica líquida compreendendo um agonista glp-1 e metionina e uso da mesma
KR101972301B1 (ko) 2009-11-13 2019-04-25 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ－１ 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물
US9457029B2 (en) 2009-11-27 2016-10-04 Boehringer Ingelheim International Gmbh Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin
BR112012028136A2 (pt) 2010-05-05 2016-08-09 Boehringer Ingelheim Int terapia de combinaçao
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CA2809321C (en) 2010-08-30 2018-08-14 Sanofi-Aventis Deutschland Gmbh Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
CN103816115B (zh) * 2010-08-31 2017-06-27 成都康弘生物科技有限公司 一种含有抑制血管增生的融合蛋白的药物组合物及用途
BR112013010345A2 (pt) 2010-10-27 2017-07-25 Novo Nordisk As tratamento de diabetes melitus usando as injeções de insulina administradas com intervalos de variação da injeção
KR101841527B1 (ko) 2010-11-11 2018-03-23 애브비 바이오테크놀로지 리미티드 개선된 고농도 항－ＴＮＦα 항체 액체 제형
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
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CN103271871A (zh) * 2013-03-18 2013-09-04 长春海伯尔生物技术有限责任公司 一种重组人干扰素注射液及其制备方法
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Also Published As

Publication number Publication date
UA93349C2 (ru) 2011-02-10
EA012281B1 (ru) 2009-08-28
EP1750750A1 (de) 2007-02-14
WO2005117948A1 (en) 2005-12-15
CN1993138B (zh) 2010-12-15
AU2005249232B2 (en) 2010-08-05
EA200602254A1 (ru) 2007-06-29
MXPA06014079A (es) 2007-02-15
JP2008500995A (ja) 2008-01-17
CA2567309A1 (en) 2005-12-15
BRPI0510527A (pt) 2007-10-30
AU2005249232A1 (en) 2005-12-15
US20070244299A1 (en) 2007-10-18
HK1102561A1 (en) 2007-11-30
ZA200610041B (en) 2008-07-30
EP1750750B1 (de) 2012-02-01
IL179617A0 (en) 2007-05-15
US7858082B2 (en) 2010-12-28
ES2381674T3 (es) 2012-05-30
CN1993138A (zh) 2007-07-04
NO20065861L (no) 2007-03-01

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