AR049333A1 - Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas. - Google Patents
Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas.Info
- Publication number
- AR049333A1 AR049333A1 ARP050101327A ARP050101327A AR049333A1 AR 049333 A1 AR049333 A1 AR 049333A1 AR P050101327 A ARP050101327 A AR P050101327A AR P050101327 A ARP050101327 A AR P050101327A AR 049333 A1 AR049333 A1 AR 049333A1
- Authority
- AR
- Argentina
- Prior art keywords
- independently
- occurrence
- nitrogen
- optionally substituted
- conr
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 5
- 125000005842 heteroatom Chemical group 0.000 abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 5
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 5
- 229910052760 oxygen Inorganic materials 0.000 abstract 5
- 239000001301 oxygen Chemical group 0.000 abstract 5
- 229920006395 saturated elastomer Polymers 0.000 abstract 5
- 229910052717 sulfur Chemical group 0.000 abstract 5
- 239000011593 sulfur Chemical group 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 4
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 125000001118 alkylidene group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000002950 monocyclic group Chemical group 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 2
- 125000002619 bicyclic group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55904104P | 2004-04-02 | 2004-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR049333A1 true AR049333A1 (es) | 2006-07-19 |
Family
ID=34983212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050101327A AR049333A1 (es) | 2004-04-02 | 2005-04-04 | Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7514448B2 (https=) |
| EP (1) | EP1756108A2 (https=) |
| JP (1) | JP5019612B2 (https=) |
| KR (1) | KR20070002081A (https=) |
| CN (1) | CN101014597A (https=) |
| AR (1) | AR049333A1 (https=) |
| AU (1) | AU2005236002A1 (https=) |
| CA (1) | CA2561724A1 (https=) |
| IL (1) | IL178414A0 (https=) |
| MX (1) | MXPA06011328A (https=) |
| NO (1) | NO20064976L (https=) |
| RU (1) | RU2006138621A (https=) |
| TW (1) | TW200604168A (https=) |
| WO (1) | WO2005103050A2 (https=) |
Families Citing this family (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2550361C (en) | 2003-12-19 | 2014-04-29 | Prabha Ibrahim | Compounds and methods for development of ret modulators |
| JP4834840B2 (ja) | 2004-01-06 | 2011-12-14 | ノヴォ ノルディスク アー／エス | ヘテロアリール尿素およびグルコキナーゼ活性化剤としてのその使用 |
| US20080293716A1 (en) * | 2004-01-30 | 2008-11-27 | Smithkline Beecham Corporation | Chemical Compounds |
| TWI372624B (en) * | 2004-03-30 | 2012-09-21 | Vertex Pharma | Azaindoles useful as inhibitors of jak and other protein kinases |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
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| KR100581199B1 (ko) | 1998-06-19 | 2006-05-17 | 카이론 코포레이션 | 글리코겐 신타제 키나제 3의 억제제 |
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| US20060122213A1 (en) * | 2004-06-30 | 2006-06-08 | Francoise Pierard | Azaindoles useful as inhibitors of protein kinases |
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2005
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- 2005-04-04 CA CA002561724A patent/CA2561724A1/en not_active Abandoned
- 2005-04-04 JP JP2007506357A patent/JP5019612B2/ja not_active Expired - Fee Related
- 2005-04-04 AU AU2005236002A patent/AU2005236002A1/en not_active Abandoned
- 2005-04-04 US US11/098,751 patent/US7514448B2/en active Active
- 2005-04-04 MX MXPA06011328A patent/MXPA06011328A/es unknown
- 2005-04-04 CN CNA2005800164388A patent/CN101014597A/zh active Pending
- 2005-04-04 TW TW094110745A patent/TW200604168A/zh unknown
- 2005-04-04 AR ARP050101327A patent/AR049333A1/es unknown
- 2005-04-04 EP EP05767612A patent/EP1756108A2/en not_active Withdrawn
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| WO2005103050A3 (en) | 2006-10-05 |
| MXPA06011328A (es) | 2006-12-15 |
| CN101014597A (zh) | 2007-08-08 |
| JP5019612B2 (ja) | 2012-09-05 |
| KR20070002081A (ko) | 2007-01-04 |
| CA2561724A1 (en) | 2005-11-03 |
| AU2005236002A1 (en) | 2005-11-03 |
| US20060003968A1 (en) | 2006-01-05 |
| TW200604168A (en) | 2006-02-01 |
| JP2007531740A (ja) | 2007-11-08 |
| RU2006138621A (ru) | 2008-05-10 |
| NO20064976L (no) | 2006-10-31 |
| IL178414A0 (en) | 2007-02-11 |
| EP1756108A2 (en) | 2007-02-28 |
| WO2005103050A2 (en) | 2005-11-03 |
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