AR021388A1 - Derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamento - Google Patents

Derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamento

Info

Publication number
AR021388A1
AR021388A1 ARP990105985A ARP990105985A AR021388A1 AR 021388 A1 AR021388 A1 AR 021388A1 AR P990105985 A ARP990105985 A AR P990105985A AR P990105985 A ARP990105985 A AR P990105985A AR 021388 A1 AR021388 A1 AR 021388A1
Authority
AR
Argentina
Prior art keywords
radicals
alkenyl
alkyl
alkynyl
erythromycin
Prior art date
Application number
ARP990105985A
Other languages
English (en)
Spanish (es)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR021388A1 publication Critical patent/AR021388A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ARP990105985A 1998-11-24 1999-11-24 Derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamento AR021388A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9814782A FR2786188B1 (fr) 1998-11-24 1998-11-24 Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments

Publications (1)

Publication Number Publication Date
AR021388A1 true AR021388A1 (es) 2002-07-17

Family

ID=9533122

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105985A AR021388A1 (es) 1998-11-24 1999-11-24 Derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamento

Country Status (24)

Country Link
US (2) US6440941B1 (enExample)
EP (1) EP1004592B1 (enExample)
JP (1) JP2000159790A (enExample)
KR (1) KR100587445B1 (enExample)
CN (1) CN1165546C (enExample)
AR (1) AR021388A1 (enExample)
AT (1) ATE245160T1 (enExample)
AU (1) AU772171B2 (enExample)
BR (1) BR9905735A (enExample)
CA (1) CA2290136C (enExample)
DE (1) DE69909577T2 (enExample)
DK (1) DK1004592T3 (enExample)
ES (1) ES2198867T3 (enExample)
FR (1) FR2786188B1 (enExample)
HU (1) HUP9904392A3 (enExample)
IL (1) IL133101A (enExample)
MX (1) MXPA99010813A (enExample)
NO (1) NO314729B1 (enExample)
PL (1) PL336736A1 (enExample)
PT (1) PT1004592E (enExample)
RU (1) RU2237672C2 (enExample)
TR (1) TR199902888A3 (enExample)
TW (1) TWI247747B (enExample)
ZA (1) ZA997176B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
CZ20012675A3 (cs) 1999-01-27 2002-04-17 Pfizer Products Inc. Ketolidová antibiotika
BR0010938A (pt) 1999-05-24 2002-03-19 Pfizer Prod Inc Derivados da 13-metil eritromicina
ES2222966T3 (es) 2000-06-30 2005-02-16 Pfizer Products Inc. Macrolidos antibioticos.
US7601695B2 (en) * 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
FR2862647B1 (fr) 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US8552162B2 (en) * 2008-05-09 2013-10-08 Enanta Pharmaceuticals, Inc. Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives
CN102245195B (zh) * 2008-10-24 2016-01-13 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
EP3009442B1 (en) 2010-03-22 2019-06-19 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
CA2799937A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
WO2012034058A1 (en) * 2010-09-10 2012-03-15 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
EP2630133A1 (de) 2010-10-22 2013-08-28 Bayer Intellectual Property GmbH Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
CA2868262A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
HK1217665A1 (zh) 2013-03-14 2017-01-20 森普拉制药公司 用於治療呼吸道疾病的方法及其製劑
HK1218864A1 (zh) 2013-03-15 2017-03-17 森普拉制药公司 用於制备大环内酯抗菌剂的收敛方法
CN106432383A (zh) * 2016-09-14 2017-02-22 重庆两江药物研发中心有限公司 索利霉素及其中间体的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182895A (en) * 1976-12-20 1980-01-08 Sterling Drug Inc. 1-Amino-lower-alkyl-3,4-diphenyl-1H-pyrazoles
CA1098527A (en) * 1976-12-20 1981-03-31 Denis M. Bailey 1-amino-lower-alkyl-3,4-diphenyl-1h-pyrazoles
JPH04234891A (ja) * 1990-03-05 1992-08-24 Fujisawa Pharmaceut Co Ltd 新規セフェム化合物およびその塩
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
CN1259135A (zh) * 1997-06-11 2000-07-05 辉瑞产品公司 9－肟红霉素衍生物
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments

Also Published As

Publication number Publication date
NO995745L (no) 2000-05-25
IL133101A (en) 2007-02-11
ZA997176B (en) 2000-11-20
DK1004592T3 (da) 2003-10-27
TWI247747B (en) 2006-01-21
RU2237672C2 (ru) 2004-10-10
AU5952299A (en) 2000-05-25
CA2290136C (fr) 2010-07-20
US6440941B1 (en) 2002-08-27
PT1004592E (pt) 2003-12-31
FR2786188A1 (fr) 2000-05-26
ATE245160T1 (de) 2003-08-15
TR199902888A2 (xx) 2000-06-21
NO314729B1 (no) 2003-05-12
TR199902888A3 (tr) 2000-06-21
BR9905735A (pt) 2000-08-08
AU772171B2 (en) 2004-04-08
CN1165546C (zh) 2004-09-08
US6664398B2 (en) 2003-12-16
KR20000057017A (ko) 2000-09-15
CN1263101A (zh) 2000-08-16
ES2198867T3 (es) 2004-02-01
FR2786188B1 (fr) 2002-10-31
NO995745D0 (no) 1999-11-23
DE69909577T2 (de) 2004-06-03
HUP9904392A3 (en) 2001-08-28
PL336736A1 (en) 2000-06-05
JP2000159790A (ja) 2000-06-13
EP1004592B1 (fr) 2003-07-16
EP1004592A1 (fr) 2000-05-31
HUP9904392A2 (hu) 2000-05-28
DE69909577D1 (de) 2003-08-21
MXPA99010813A (es) 2005-09-08
CA2290136A1 (fr) 2000-05-24
IL133101A0 (en) 2001-03-19
KR100587445B1 (ko) 2006-06-08
HU9904392D0 (en) 2000-01-28
US20030050254A1 (en) 2003-03-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal