HUP9904392A3 - New derivatives of erythromycin, process for their production and their use as medicament - Google Patents
New derivatives of erythromycin, process for their production and their use as medicamentInfo
- Publication number
- HUP9904392A3 HUP9904392A3 HU9904392A HUP9904392A HUP9904392A3 HU P9904392 A3 HUP9904392 A3 HU P9904392A3 HU 9904392 A HU9904392 A HU 9904392A HU P9904392 A HUP9904392 A HU P9904392A HU P9904392 A3 HUP9904392 A3 HU P9904392A3
- Authority
- HU
- Hungary
- Prior art keywords
- erythromycin
- medicament
- production
- new derivatives
- derivatives
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9814782A FR2786188B1 (fr) | 1998-11-24 | 1998-11-24 | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9904392D0 HU9904392D0 (en) | 2000-01-28 |
HUP9904392A2 HUP9904392A2 (hu) | 2000-05-28 |
HUP9904392A3 true HUP9904392A3 (en) | 2001-08-28 |
Family
ID=9533122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9904392A HUP9904392A3 (en) | 1998-11-24 | 1999-11-23 | New derivatives of erythromycin, process for their production and their use as medicament |
Country Status (24)
Country | Link |
---|---|
US (2) | US6440941B1 (hu) |
EP (1) | EP1004592B1 (hu) |
JP (1) | JP2000159790A (hu) |
KR (1) | KR100587445B1 (hu) |
CN (1) | CN1165546C (hu) |
AR (1) | AR021388A1 (hu) |
AT (1) | ATE245160T1 (hu) |
AU (1) | AU772171B2 (hu) |
BR (1) | BR9905735A (hu) |
CA (1) | CA2290136C (hu) |
DE (1) | DE69909577T2 (hu) |
DK (1) | DK1004592T3 (hu) |
ES (1) | ES2198867T3 (hu) |
FR (1) | FR2786188B1 (hu) |
HU (1) | HUP9904392A3 (hu) |
IL (1) | IL133101A (hu) |
MX (1) | MXPA99010813A (hu) |
NO (1) | NO314729B1 (hu) |
PL (1) | PL336736A1 (hu) |
PT (1) | PT1004592E (hu) |
RU (1) | RU2237672C2 (hu) |
TR (1) | TR199902888A2 (hu) |
TW (1) | TWI247747B (hu) |
ZA (1) | ZA997176B (hu) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2786188B1 (fr) * | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
SI1147121T1 (en) | 1999-01-27 | 2004-04-30 | Pfizer Products Inc. | Ketolide antibiotics |
EE200100613A (et) | 1999-05-24 | 2003-02-17 | Pfizer Products Inc. | 13-metüülerütromütsiini derivaadid |
TR200401847T4 (tr) | 2000-06-30 | 2004-09-21 | Pfizer Products Inc. | Makrolit antibiyotikler. |
EP2772254A3 (en) | 2003-03-10 | 2015-03-11 | Optimer Pharmaceuticals, Inc. | Novel Antibacterial Agents |
FR2862647B1 (fr) | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
US20080287376A1 (en) * | 2004-07-28 | 2008-11-20 | Mohammad Salman | Ketolide Derivatives as Antibacterial Agents |
JP5698979B2 (ja) * | 2007-10-25 | 2015-04-08 | センプラ ファーマシューティカルズ,インコーポレイテッド | マクロライド系抗菌剤の調製プロセス |
US8552162B2 (en) * | 2008-05-09 | 2013-10-08 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives |
CN105616437A (zh) * | 2008-10-24 | 2016-06-01 | 森普拉制药公司 | 使用含三唑的大环内酯的生物防御 |
US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
CN108310000A (zh) | 2009-09-10 | 2018-07-24 | 森普拉制药公司 | 治疗疟疾、结核病和mac疾病的方法 |
EP3009442B1 (en) | 2010-03-22 | 2019-06-19 | Cempra Pharmaceuticals, Inc. | Crystalline forms of a macrolide, and uses therefor |
DK2571506T3 (en) | 2010-05-20 | 2017-08-28 | Cempra Pharmaceuticals Inc | PROCEDURES FOR THE MANUFACTURE OF MACROLIDES AND KETOLIDES AND INTERMEDIATES |
US9815863B2 (en) * | 2010-09-10 | 2017-11-14 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
WO2012052412A1 (de) | 2010-10-22 | 2012-04-26 | Bayer Cropscience Ag | Neue heterocylische verbindungen als schädlingsbekämpfungsmittel |
RU2658050C2 (ru) | 2012-03-27 | 2018-06-19 | Семпра Фармасьютикалз, Инк. | Парентеральные составы для введения макролидных антибиотиков |
JP6426696B2 (ja) | 2013-03-14 | 2018-11-21 | センプラ ファーマシューティカルズ,インコーポレイテッド | 呼吸器疾患の治療のための方法および製剤 |
CA2907085A1 (en) | 2013-03-15 | 2014-09-18 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
CN106432383A (zh) * | 2016-09-14 | 2017-02-22 | 重庆两江药物研发中心有限公司 | 索利霉素及其中间体的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4182895A (en) * | 1976-12-20 | 1980-01-08 | Sterling Drug Inc. | 1-Amino-lower-alkyl-3,4-diphenyl-1H-pyrazoles |
CA1098527A (en) * | 1976-12-20 | 1981-03-31 | Denis M. Bailey | 1-amino-lower-alkyl-3,4-diphenyl-1h-pyrazoles |
JPH04234891A (ja) * | 1990-03-05 | 1992-08-24 | Fujisawa Pharmaceut Co Ltd | 新規セフェム化合物およびその塩 |
US5527780A (en) * | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
FR2718450B1 (fr) * | 1994-04-08 | 1997-01-10 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
FR2719587B1 (fr) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
FR2727969B1 (fr) * | 1994-12-09 | 1997-01-17 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
FR2742757B1 (fr) * | 1995-12-22 | 1998-01-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
JP2000513026A (ja) * | 1997-06-11 | 2000-10-03 | ファイザー・プロダクツ・インク | 9−オキシム エリスロマイシン誘導体 |
FR2786188B1 (fr) * | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
-
1998
- 1998-11-24 FR FR9814782A patent/FR2786188B1/fr not_active Expired - Fee Related
-
1999
- 1999-11-16 TW TW088119939A patent/TWI247747B/zh not_active IP Right Cessation
- 1999-11-17 AU AU59522/99A patent/AU772171B2/en not_active Expired
- 1999-11-18 CA CA2290136A patent/CA2290136C/fr not_active Expired - Lifetime
- 1999-11-18 US US09/442,681 patent/US6440941B1/en not_active Expired - Lifetime
- 1999-11-18 ZA ZA9907176A patent/ZA997176B/xx unknown
- 1999-11-22 JP JP11331141A patent/JP2000159790A/ja active Pending
- 1999-11-23 MX MXPA99010813A patent/MXPA99010813A/es active IP Right Grant
- 1999-11-23 AT AT99402907T patent/ATE245160T1/de active
- 1999-11-23 RU RU99125547A patent/RU2237672C2/ru not_active IP Right Cessation
- 1999-11-23 IL IL133101A patent/IL133101A/en not_active IP Right Cessation
- 1999-11-23 EP EP99402907A patent/EP1004592B1/fr not_active Expired - Lifetime
- 1999-11-23 ES ES99402907T patent/ES2198867T3/es not_active Expired - Lifetime
- 1999-11-23 DE DE69909577T patent/DE69909577T2/de not_active Expired - Lifetime
- 1999-11-23 CN CNB99127394XA patent/CN1165546C/zh not_active Expired - Lifetime
- 1999-11-23 PT PT99402907T patent/PT1004592E/pt unknown
- 1999-11-23 HU HU9904392A patent/HUP9904392A3/hu unknown
- 1999-11-23 NO NO19995745A patent/NO314729B1/no unknown
- 1999-11-23 KR KR1019990052014A patent/KR100587445B1/ko active IP Right Grant
- 1999-11-23 DK DK99402907T patent/DK1004592T3/da active
- 1999-11-24 AR ARP990105985A patent/AR021388A1/es not_active Application Discontinuation
- 1999-11-24 TR TR1999/02888A patent/TR199902888A2/xx unknown
- 1999-11-24 BR BR9905735-2A patent/BR9905735A/pt active Search and Examination
- 1999-11-24 PL PL99336736A patent/PL336736A1/xx not_active Application Discontinuation
-
2002
- 2002-07-02 US US10/188,394 patent/US6664398B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1046681A1 (en) | 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use | |
HU9904392D0 (en) | New derivatives of erythromycin, process for their production and their use as medicament | |
HU9802224D0 (en) | Pyrazol derivatives, process for producing them and their use as medicament | |
HUP0202472A3 (en) | Sulfonyl carboxiamide derivatives, method for their production and their use as medicaments | |
HK1040708A1 (en) | Aryl-substituted propanolamine derivatives, methods for their production, medicaments containing said compounds and their use | |
SI0680967T1 (en) | Erythromycin derivatives, their process of preparation and their use as medicaments | |
HUP0000748A3 (en) | 4-phenyl-piridine derivatives, process for producing them and pharmaceutical compositions containing them | |
IL112954A0 (en) | New erythromycin derivatives, their preparation process and their use as medicaments | |
HUP9900120A3 (en) | Benzosulfone derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP0105136A3 (en) | Amide derivatives, process for their preparation and medicaments containing them | |
HUP0201225A2 (en) | 4,5,6,7-tetrahydroindazole derivatives as antitumor agent and process for their preparation | |
IL142996A0 (en) | New derivatives of erythromycin, their preparation process and their use as medicaments | |
HUP0100978A3 (en) | Benzothiadiazoles and derivatives, process for their preparation and medicaments containing them | |
HUP0105479A3 (en) | Betha-alanine derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP0201785A3 (en) | Dihydrobenzodiazepins, process for producing them, their use and pharmaceutical compositions containing them | |
HUP0103316A3 (en) | 2-ureido-pyrimidone derivatives, method for producing them, pharmaceutical compositions containing them and their use | |
HUP0104620A3 (en) | 2-phenylpyran-4-one derivatives, process for their preparation and medicaments containing them | |
HUP0003861A3 (en) | Quinolin-4-yl derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP0201916A2 (en) | Ethanesulfonyl-piperidine derivatives, process for producing them and pharmaceutical compositions containing them | |
AU3853597A (en) | New derivatives of erythromycin, their preparation process and their use as medicaments | |
AU5487798A (en) | New derivatives of erythromycin, their preparation process and their use as medicaments | |
HUP9904564A3 (en) | Substituted aminomethyl-cycloheptenes, process for producing them, their use, and pharmaceutical compositions containing them | |
HUP0200643A3 (en) | Dibenzoazulene derivatives, pharmaceutical compositions containing them, process for producing them and use of them for producing pharmaceutical compositions | |
HU0001178D0 (en) | New propene-carbon acid-amidoxim derivatives, process for their production and medicaments containing the same | |
HUP9801545A3 (en) | 4-amino-2-methyl-isothiazol-3-one derivatives, cystinediamides and process for producing them, and use of the compounds |