AR020029A1 - Procedimiento para preparar 2-fenil-3-aminopiridina, derivados fenilo sustituidos de la misma. - Google Patents

Procedimiento para preparar 2-fenil-3-aminopiridina, derivados fenilo sustituidos de la misma.

Info

Publication number
AR020029A1
AR020029A1 ARP000102332A ARP000102332A AR020029A1 AR 020029 A1 AR020029 A1 AR 020029A1 AR P000102332 A ARP000102332 A AR P000102332A AR P000102332 A ARP000102332 A AR P000102332A AR 020029 A1 AR020029 A1 AR 020029A1
Authority
AR
Argentina
Prior art keywords
compound
phenyl
formula
aminopiridine
prepare
Prior art date
Application number
ARP000102332A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020029A1 publication Critical patent/AR020029A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un procedimiento para preparar 2-fenil-3-aminopiridina, derivados fenilo sustituidos de la misma y sales de dichos compuestos. Un compuesto deformula (1) o (2), se hace reaccionar con un compuesto de formula (3), en un disolvente inerte a lareaccion , en presencia de una base y un catalizador depaladio, para obtener un compuesto de formula (4) o (5). Preferiblemente, el compuesto de formula (1) o (2) se prepara mediante la reaccion deun compuesto de formula (6), con un compuesto deformula (7) o (8), en un disolvente inerte a la reaccion. Preferiblemente, el compuesto de formula (4)se desprotege en ácido acuoso para obtener una sal del compuesto X. X, Y, Z, Ar, R1, R2, R3, R4 y R5 son como se definen en la memoria descriptiva.
ARP000102332A 1999-05-17 2000-05-15 Procedimiento para preparar 2-fenil-3-aminopiridina, derivados fenilo sustituidos de la misma. AR020029A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13455999P 1999-05-17 1999-05-17

Publications (1)

Publication Number Publication Date
AR020029A1 true AR020029A1 (es) 2002-03-27

Family

ID=22463902

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102332A AR020029A1 (es) 1999-05-17 2000-05-15 Procedimiento para preparar 2-fenil-3-aminopiridina, derivados fenilo sustituidos de la misma.

Country Status (26)

Country Link
US (1) US6316632B1 (es)
EP (1) EP1054002B1 (es)
JP (1) JP3837011B2 (es)
KR (1) KR100386226B1 (es)
CN (1) CN1216865C (es)
AR (1) AR020029A1 (es)
AT (1) ATE306474T1 (es)
AU (1) AU775947B2 (es)
BR (1) BR0001773A (es)
CA (1) CA2308817C (es)
CZ (1) CZ299474B6 (es)
DE (1) DE60023063T2 (es)
DK (1) DK1054002T3 (es)
ES (1) ES2248017T3 (es)
HK (1) HK1032397A1 (es)
HU (1) HUP0001928A3 (es)
ID (1) ID26061A (es)
IL (1) IL136105A (es)
IN (1) IN192341B (es)
MX (1) MXPA00004790A (es)
PL (1) PL198153B1 (es)
RS (1) RS49964B (es)
RU (1) RU2181120C2 (es)
TR (1) TR200001403A2 (es)
TW (1) TWI286133B (es)
ZA (1) ZA200002375B (es)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
CZ293955B6 (cs) 1991-03-26 2004-08-18 Pfizeráinc Postup přípravy substituovaných piperidinů
DE9290083U1 (de) 1991-06-20 1994-02-17 Pfizer Fluoralkoxybenzylamino-Derivate von stickstoffhaltigen Heterocyclen
WO1997003066A1 (en) 1995-07-07 1997-01-30 Pfizer Pharmaceuticals Inc. Substituted benzolactam compounds as substance p antagonists
TW340842B (en) 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
JP2001508412A (ja) 1996-12-02 2001-06-26 メルク シヤープ エンド ドーム リミテツド 認識障害の治療のためのｎｋ−１受容体拮抗薬の使用
TW426667B (en) 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

Also Published As

Publication number Publication date
IL136105A0 (en) 2001-05-20
IL136105A (en) 2006-07-05
MXPA00004790A (es) 2002-03-08
CZ20001800A3 (cs) 2001-03-14
EP1054002A1 (en) 2000-11-22
ATE306474T1 (de) 2005-10-15
DE60023063D1 (de) 2006-02-23
HUP0001928A2 (en) 2001-03-28
CN1216865C (zh) 2005-08-31
YU19600A (sh) 2002-03-18
PL198153B1 (pl) 2008-05-30
AU775947B2 (en) 2004-08-19
TR200001403A2 (tr) 2000-12-21
KR100386226B1 (ko) 2003-06-02
HU0001928D0 (en) 2000-07-28
CZ299474B6 (cs) 2008-08-06
ES2248017T3 (es) 2006-03-16
IN192341B (es) 2004-04-10
DK1054002T3 (da) 2006-02-20
HK1032397A1 (en) 2001-07-20
US6316632B1 (en) 2001-11-13
BR0001773A (pt) 2001-01-02
RU2181120C2 (ru) 2002-04-10
RS49964B (sr) 2008-09-29
JP3837011B2 (ja) 2006-10-25
JP2000355584A (ja) 2000-12-26
KR20010020845A (ko) 2001-03-15
HUP0001928A3 (en) 2002-05-28
PL340157A1 (en) 2000-11-20
CA2308817C (en) 2005-06-14
CN1288005A (zh) 2001-03-21
AU2766200A (en) 2000-11-23
ZA200002375B (en) 2001-11-15
EP1054002B1 (en) 2005-10-12
TWI286133B (en) 2007-09-01
DE60023063T2 (de) 2006-04-20
ID26061A (id) 2000-11-23
CA2308817A1 (en) 2000-11-17

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