ES2190610T3 - Sintesis de 3-carbometoxi-4,5-dimetiltiofeno. - Google Patents

Sintesis de 3-carbometoxi-4,5-dimetiltiofeno.

Info

Publication number
ES2190610T3
ES2190610T3 ES98951049T ES98951049T ES2190610T3 ES 2190610 T3 ES2190610 T3 ES 2190610T3 ES 98951049 T ES98951049 T ES 98951049T ES 98951049 T ES98951049 T ES 98951049T ES 2190610 T3 ES2190610 T3 ES 2190610T3
Authority
ES
Spain
Prior art keywords
alkyl
aryl
group
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98951049T
Other languages
English (en)
Inventor
Thomas L Fevig
Patrick H Lau
Wendell G Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Technology LLC
Original Assignee
Monsanto Technology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology LLC filed Critical Monsanto Technology LLC
Application granted granted Critical
Publication of ES2190610T3 publication Critical patent/ES2190610T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid

Abstract

Un procedimiento para la preparación de un compuesto de tiofeno sustituido que tiene la fórmula: en la que: R1 y R2 se seleccionan independientemente del grupo constituido por H, alquilo, arilo, alquilo o arilo sustituido, y un anillo que combina R1 y R2; R3 se selecciona del grupo constituido por H, alquilo, arilo y los equivalentes sustituidos de los mismos; Z es CN o CO2R4, en la que R4 se elige del grupo constituido por alquilo y arilo y los equivalentes sustituidos de los mismos, H, Na, Li y NH4+; que comprende: (a) (1) hacer reaccionar una mercaptocetona que tiene la fórmula en el que: R1 y R2 son como se ha definido anteriormente con un compuesto acrílico que tiene la fórmula en el que: R3 se ha definido anteriormente A se selecciona del grupo constituido por alcoxi, en presencia de una cantidad eficaz de una base como catalizador, (b) aromatizar mediante tratamiento ácido; y (c) recuperar el tiofeno producto sustituido.
ES98951049T 1997-10-14 1998-10-13 Sintesis de 3-carbometoxi-4,5-dimetiltiofeno. Expired - Lifetime ES2190610T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6197297P 1997-10-14 1997-10-14

Publications (1)

Publication Number Publication Date
ES2190610T3 true ES2190610T3 (es) 2003-08-01

Family

ID=22039390

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98951049T Expired - Lifetime ES2190610T3 (es) 1997-10-14 1998-10-13 Sintesis de 3-carbometoxi-4,5-dimetiltiofeno.

Country Status (16)

Country Link
US (2) US6084108A (es)
EP (1) EP1023283B1 (es)
CN (1) CN1116294C (es)
AT (1) ATE231853T1 (es)
AU (1) AU9694298A (es)
CA (1) CA2306910C (es)
CZ (1) CZ297978B6 (es)
DE (1) DE69811103T2 (es)
DK (1) DK1023283T3 (es)
EA (1) EA003088B1 (es)
ES (1) ES2190610T3 (es)
HU (1) HU228367B1 (es)
PL (1) PL205200B1 (es)
UA (1) UA57810C2 (es)
WO (1) WO1999019321A1 (es)
ZA (1) ZA989348B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6992047B2 (en) * 2001-04-11 2006-01-31 Monsanto Technology Llc Method of microencapsulating an agricultural active having a high melting point and uses for such materials
DE10148437A1 (de) * 2001-10-01 2003-04-17 Bayer Ag Verfahren zur Alkylierung von 3,4-Dihydroxythiophen-2,5-dicarbonsäureestern
CN103044479B (zh) * 2012-12-12 2015-09-02 河南农业大学 杀菌剂硅噻菌胺的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2422498A1 (de) * 1973-05-18 1974-12-05 Ciba Geigy Ag Neue thiaprostaglandine und verfahren zu ihrer herstellung
SU663299A3 (ru) * 1975-05-27 1979-05-15 Ю.Ц.Б.С.А. (Фирма) Способ получени бензил-2,2-диметокси ацетамидов
DE3229538A1 (de) * 1982-08-07 1984-02-09 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von sterisch einheitlichen 3-hydroxycarbonsaeuren bzw. deren estern
US4689343A (en) * 1983-12-09 1987-08-25 Bayer Aktiengesellschaft Novel thiolane-2,4-dione-3-carboxamide fungicides
US5206375A (en) * 1985-03-02 1993-04-27 Basf Aktiengesellschaft Thiophene derivatives
GB8609452D0 (en) * 1986-04-17 1986-05-21 Ici Plc Fungicides
DE3901074A1 (de) * 1989-01-16 1990-07-19 Basf Ag Thiophen-2-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
US5087288A (en) * 1990-09-17 1992-02-11 Eastman Kodak Company Herbicidal thioparaconic acid derivatives
US5679801A (en) * 1991-04-12 1997-10-21 American Home Products Corporation Tetronic and thiotetronic acid derivatives as phospholipase A2 inhibitors
AU664392B2 (en) * 1991-10-18 1995-11-16 Monsanto Technology Llc Fungicides for the control of take-all disease of plants
JP3337728B2 (ja) * 1992-11-20 2002-10-21 イハラケミカル工業株式会社 ２‐アセチルベンゾ［ｂ］チオフェンの製造方法
US5486621A (en) * 1994-12-15 1996-01-23 Monsanto Company Fungicides for the control of take-all disease of plants
US5747518A (en) * 1995-04-11 1998-05-05 Mitsui Toatsu Chemicals, Inc. Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient

Also Published As

Publication number Publication date
DE69811103D1 (de) 2003-03-06
ZA989348B (en) 1999-07-01
DK1023283T3 (da) 2003-06-23
HUP0003988A3 (en) 2003-01-28
EA003088B1 (ru) 2002-12-26
WO1999019321A1 (en) 1999-04-22
PL205200B1 (pl) 2010-03-31
PL339914A1 (en) 2001-01-15
UA57810C2 (uk) 2003-07-15
CN1281446A (zh) 2001-01-24
US6037478A (en) 2000-03-14
HU228367B1 (en) 2013-03-28
US6084108A (en) 2000-07-04
EP1023283B1 (en) 2003-01-29
CZ20001330A3 (cs) 2000-09-13
CN1116294C (zh) 2003-07-30
CA2306910A1 (en) 1999-04-22
EA200000415A1 (ru) 2000-10-30
CA2306910C (en) 2008-07-29
HUP0003988A2 (hu) 2002-01-28
EP1023283A1 (en) 2000-08-02
ATE231853T1 (de) 2003-02-15
AU9694298A (en) 1999-05-03
DE69811103T2 (de) 2003-10-09
CZ297978B6 (cs) 2007-05-16

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