AR015952A1 - Metodo para preparar acidos 4-fenil-4-cianociclohexanoicos sustituidos - Google Patents

Metodo para preparar acidos 4-fenil-4-cianociclohexanoicos sustituidos

Info

Publication number
AR015952A1
AR015952A1 ARP980105002A ARP980105002A AR015952A1 AR 015952 A1 AR015952 A1 AR 015952A1 AR P980105002 A ARP980105002 A AR P980105002A AR P980105002 A ARP980105002 A AR P980105002A AR 015952 A1 AR015952 A1 AR 015952A1
Authority
AR
Argentina
Prior art keywords
cyanociclohexanoicos
phenyl
substituted
preparing
preparing acids
Prior art date
Application number
ARP980105002A
Other languages
English (en)
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR015952A1 publication Critical patent/AR015952A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ARP980105002A 1997-10-10 1998-10-07 Metodo para preparar acidos 4-fenil-4-cianociclohexanoicos sustituidos AR015952A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6161397P 1997-10-10 1997-10-10

Publications (1)

Publication Number Publication Date
AR015952A1 true AR015952A1 (es) 2001-05-30

Family

ID=22036929

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980105002A AR015952A1 (es) 1997-10-10 1998-10-07 Metodo para preparar acidos 4-fenil-4-cianociclohexanoicos sustituidos

Country Status (30)

Country Link
EP (1) EP1043930A4 (de)
JP (1) JP2001519363A (de)
KR (1) KR100560038B1 (de)
CN (1) CN1192025C (de)
AP (1) AP1335A (de)
AR (1) AR015952A1 (de)
AU (1) AU741832B2 (de)
BG (1) BG104302A (de)
BR (1) BR9814064A (de)
CA (1) CA2305614A1 (de)
DZ (1) DZ2619A1 (de)
EA (1) EA003609B1 (de)
HU (1) HUP0003905A3 (de)
ID (1) ID25536A (de)
IL (1) IL135434A (de)
MA (1) MA24670A1 (de)
MY (1) MY122105A (de)
NO (1) NO20001777L (de)
NZ (1) NZ503759A (de)
OA (1) OA11347A (de)
PE (1) PE121599A1 (de)
PL (1) PL191974B1 (de)
SA (1) SA99191000A (de)
SK (1) SK4902000A3 (de)
TR (1) TR200000945T2 (de)
TW (1) TW440557B (de)
UA (1) UA67753C2 (de)
UY (2) UY25201A1 (de)
WO (1) WO1999018793A1 (de)
ZA (1) ZA989228B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920152D0 (en) * 1999-08-25 1999-10-27 Smithkline Beecham Plc Novel process
EP1237851A4 (de) * 1999-12-15 2004-06-23 Smithkline Beecham Salze der i cis/i-4-cyano-4-3-(cyclopentyloxy)-4-methoxyphenyl]cyclhexan-1-carbonsäure
WO2001055094A1 (en) * 2000-01-26 2001-08-02 Smithkline Beecham Corporation Monohydrate of cis-lithium-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylate
EP1265861A2 (de) 2000-03-16 2002-12-18 Inflazyme Pharmaceuticals, Ltd. Benzylierte pde4-inhibitoren
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
BR0116845A (pt) 2001-01-31 2004-02-25 Pfizer Prod Inc Derivados éter úteis como inibidores de isozimas pde4
BR0116852A (pt) 2001-01-31 2004-02-25 Pfizer Prod Inc Derivados biarilados de nicotinamida úteis como inibidores de isozimas pde4
EA200300622A1 (ru) 2001-01-31 2003-12-25 Пфайзер Продактс Инк. Производные амидов тиазолил-, оксазолил, пирролил- и имидазолилкислот, полезные в качестве ингибиторов изоферментов pde4
CN102491959B (zh) * 2011-12-19 2015-03-25 江苏澄扬作物科技有限公司 一种环氧乙烷衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021478A (en) * 1972-07-13 1977-05-03 The Upjohn Company Preparation of carboxylic acids from glycidonitriles with ionic lewis acids
SK279958B6 (sk) * 1992-04-02 1999-06-11 Smithkline Beecham Corporation Zlúčeniny s protialergickým a protizápalovým účink
US5524438A (en) * 1994-12-15 1996-06-11 United Technologies Corporation Segmented bulkhead liner for a gas turbine combustor
UY24882A1 (es) * 1997-02-12 2001-08-27 Smithkline Beecham Corp Ácidos 4-fenil-4-ciano-ciclohexanoicos sustituidos
US6452022B1 (en) * 1997-10-10 2002-09-17 Smithkline Beecham Corporation Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Also Published As

Publication number Publication date
AU9687498A (en) 1999-05-03
OA11347A (en) 2003-12-17
TW440557B (en) 2001-06-16
AU741832B2 (en) 2001-12-13
JP2001519363A (ja) 2001-10-23
PL191974B1 (pl) 2006-07-31
HUP0003905A3 (en) 2002-01-28
UY25201A1 (es) 2001-08-27
UA67753C2 (uk) 2004-07-15
MA24670A1 (fr) 1999-07-01
EP1043930A1 (de) 2000-10-18
DZ2619A1 (fr) 2003-03-08
EA003609B1 (ru) 2003-06-26
CN1192025C (zh) 2005-03-09
EP1043930A4 (de) 2004-09-15
AP2000001782A0 (en) 2000-06-30
BG104302A (en) 2001-08-31
NO20001777D0 (no) 2000-04-06
ZA989228B (en) 1999-04-12
IL135434A0 (en) 2001-05-20
UY25524A1 (es) 2000-02-23
CN1275052A (zh) 2000-11-29
AP1335A (en) 2004-11-29
KR20010015709A (ko) 2001-02-26
NO20001777L (no) 2000-05-03
PE121599A1 (es) 2000-02-19
SK4902000A3 (en) 2000-11-07
CA2305614A1 (en) 1999-04-22
EA200000406A1 (ru) 2000-10-30
BR9814064A (pt) 2000-09-26
PL339759A1 (en) 2001-01-02
SA99191000A (ar) 2005-12-03
NZ503759A (en) 2002-03-01
HUP0003905A2 (en) 2001-03-28
KR100560038B1 (ko) 2006-03-13
IL135434A (en) 2004-12-15
ID25536A (id) 2000-10-12
TR200000945T2 (tr) 2000-10-23
MY122105A (en) 2006-03-31
WO1999018793A1 (en) 1999-04-22

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