HUP0003905A3 - Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids - Google Patents
Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acidsInfo
- Publication number
- HUP0003905A3 HUP0003905A3 HU0003905A HUP0003905A HUP0003905A3 HU P0003905 A3 HUP0003905 A3 HU P0003905A3 HU 0003905 A HU0003905 A HU 0003905A HU P0003905 A HUP0003905 A HU P0003905A HU P0003905 A3 HUP0003905 A3 HU P0003905A3
- Authority
- HU
- Hungary
- Prior art keywords
- phenyl
- preparing substituted
- cyanocyclohexanoic
- acids
- cyanocyclohexanoic acids
- Prior art date
Links
- XWFKZQVEYDVFTA-UHFFFAOYSA-N 4-cyano-4-phenylcyclohexane-1-carboxylic acid Chemical class C1CC(C(=O)O)CCC1(C#N)C1=CC=CC=C1 XWFKZQVEYDVFTA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6161397P | 1997-10-10 | 1997-10-10 | |
| PCT/US1998/021061 WO1999018793A1 (en) | 1997-10-10 | 1998-10-07 | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0003905A2 HUP0003905A2 (en) | 2001-03-28 |
| HUP0003905A3 true HUP0003905A3 (en) | 2002-01-28 |
Family
ID=22036929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0003905A HUP0003905A3 (en) | 1997-10-10 | 1998-10-07 | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1043930A4 (en) |
| JP (1) | JP2001519363A (en) |
| KR (1) | KR100560038B1 (en) |
| CN (1) | CN1192025C (en) |
| AP (1) | AP1335A (en) |
| AR (1) | AR015952A1 (en) |
| AU (1) | AU741832B2 (en) |
| BG (1) | BG104302A (en) |
| BR (1) | BR9814064A (en) |
| CA (1) | CA2305614A1 (en) |
| DZ (1) | DZ2619A1 (en) |
| EA (1) | EA003609B1 (en) |
| HU (1) | HUP0003905A3 (en) |
| ID (1) | ID25536A (en) |
| IL (1) | IL135434A (en) |
| MA (1) | MA24670A1 (en) |
| MY (1) | MY122105A (en) |
| NO (1) | NO20001777L (en) |
| NZ (1) | NZ503759A (en) |
| OA (1) | OA11347A (en) |
| PE (1) | PE121599A1 (en) |
| PL (1) | PL191974B1 (en) |
| SA (1) | SA99191000A (en) |
| SK (1) | SK4902000A3 (en) |
| TR (1) | TR200000945T2 (en) |
| TW (1) | TW440557B (en) |
| UA (1) | UA67753C2 (en) |
| UY (2) | UY25201A1 (en) |
| WO (1) | WO1999018793A1 (en) |
| ZA (1) | ZA989228B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9920152D0 (en) * | 1999-08-25 | 1999-10-27 | Smithkline Beecham Plc | Novel process |
| EP1237851A4 (en) * | 1999-12-15 | 2004-06-23 | Smithkline Beecham | SALTS OF i Cis /i -4-CYANO-4- 3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]CYCLOHEXANE-1-CARBOXYLIC ACID |
| OA12159A (en) * | 2000-01-26 | 2006-05-08 | Smithkline Beecham Corp | Monohydrate of cis-lithium-cyano-4-Ä3-(cyclopentyloxy)-4-methoxyphenylÜcyclohexanecar-boxylate. |
| US6555572B2 (en) | 2000-03-16 | 2003-04-29 | Inflazyme Pharmaceuticals Ltd. | Benzylated PDE4 inhibitors |
| IL156412A0 (en) | 2001-01-31 | 2004-01-04 | Pfizer Prod Inc | Thiazolyl-, oxazolyl-, pyrrolyl-, and imidazolyl-acid amide derivatives useful as inhibitors of pde4 isozymes |
| SK8942003A3 (en) | 2001-01-31 | 2004-10-05 | Pfizer Prod Inc | Ether derivatives useful as inhibitors |
| US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
| HUP0400637A2 (en) | 2001-01-31 | 2004-06-28 | Pfizer Products Inc. | Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes and pharmaceutical compositions containing them |
| CN102491959B (en) * | 2011-12-19 | 2015-03-25 | 江苏澄扬作物科技有限公司 | Preparation method of oxirane derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021478A (en) * | 1972-07-13 | 1977-05-03 | The Upjohn Company | Preparation of carboxylic acids from glycidonitriles with ionic lewis acids |
| EP0633776B1 (en) * | 1992-04-02 | 2001-05-09 | Smithkline Beecham Corporation | Compounds useful for treating allergic and inflammatory diseases |
| US5524438A (en) * | 1994-12-15 | 1996-06-11 | United Technologies Corporation | Segmented bulkhead liner for a gas turbine combustor |
| AR012550A1 (en) * | 1997-02-12 | 2000-11-08 | Smithkline Beecham Corp | METHOD FOR PREPARING SUBSTITUTED 4-PHENYL-4-CIANO-CYCLOHEXANOIC ACIDS AND INTERMEDIATE COMPOUNDS |
| US6452022B1 (en) * | 1997-10-10 | 2002-09-17 | Smithkline Beecham Corporation | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
-
1998
- 1998-07-10 UA UA2000041944A patent/UA67753C2/en unknown
- 1998-10-02 MA MA25278A patent/MA24670A1/en unknown
- 1998-10-07 JP JP2000515437A patent/JP2001519363A/en active Pending
- 1998-10-07 SK SK490-2000A patent/SK4902000A3/en unknown
- 1998-10-07 NZ NZ503759A patent/NZ503759A/en unknown
- 1998-10-07 CA CA002305614A patent/CA2305614A1/en not_active Abandoned
- 1998-10-07 DZ DZ980229A patent/DZ2619A1/en active
- 1998-10-07 PL PL339759A patent/PL191974B1/en not_active IP Right Cessation
- 1998-10-07 BR BR9814064-7A patent/BR9814064A/en not_active IP Right Cessation
- 1998-10-07 ID IDW20000614A patent/ID25536A/en unknown
- 1998-10-07 HU HU0003905A patent/HUP0003905A3/en not_active Application Discontinuation
- 1998-10-07 IL IL13543498A patent/IL135434A/en not_active IP Right Cessation
- 1998-10-07 WO PCT/US1998/021061 patent/WO1999018793A1/en not_active Application Discontinuation
- 1998-10-07 KR KR1020007003742A patent/KR100560038B1/en not_active IP Right Cessation
- 1998-10-07 AU AU96874/98A patent/AU741832B2/en not_active Ceased
- 1998-10-07 AP APAP/P/2000/001782A patent/AP1335A/en active
- 1998-10-07 EP EP98950965A patent/EP1043930A4/en not_active Withdrawn
- 1998-10-07 TR TR2000/00945T patent/TR200000945T2/en unknown
- 1998-10-07 UY UY25201A patent/UY25201A1/en not_active IP Right Cessation
- 1998-10-07 EA EA200000406A patent/EA003609B1/en not_active IP Right Cessation
- 1998-10-07 CN CNB988100304A patent/CN1192025C/en not_active Expired - Fee Related
- 1998-10-07 AR ARP980105002A patent/AR015952A1/en unknown
- 1998-10-08 MY MYPI98004606A patent/MY122105A/en unknown
- 1998-10-09 ZA ZA989228A patent/ZA989228B/en unknown
- 1998-10-09 PE PE1998000955A patent/PE121599A1/en not_active Application Discontinuation
- 1998-12-01 TW TW087116680A patent/TW440557B/en not_active IP Right Cessation
-
1999
- 1999-01-26 SA SA99191000A patent/SA99191000A/en unknown
- 1999-05-25 UY UY25524A patent/UY25524A1/en not_active Application Discontinuation
-
2000
- 2000-04-05 BG BG104302A patent/BG104302A/en unknown
- 2000-04-06 NO NO20001777A patent/NO20001777L/en not_active Application Discontinuation
- 2000-04-07 OA OA1200000100A patent/OA11347A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0004251A3 (en) | Method for preparing bromomethyl-biphenyl derivatives | |
| IL131000A0 (en) | Method for preparing oxy-diphthalic anhydrides | |
| HUP0000456A3 (en) | Method for preparing cyclopropylamines | |
| IL166185A0 (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
| GB9713283D0 (en) | Method for preparing aminoalkoxysiloxanes | |
| AP2000001782A0 (en) | Method for preparing substituted 4-phenyl-4-cyanoccyclohexanoic acids | |
| EG23935A (en) | Process for preparing eprosartin | |
| EG22077A (en) | Process for preparing 4-substituted-ih-indole-3 glyoxamides | |
| IL132729A0 (en) | Method for preparing formylphosphonic acid | |
| IL134507A0 (en) | Method for preparing oxazaphosphorin-2-amines | |
| ZA9810859B (en) | Process for preparing dialkylphosphinic acids. | |
| HUP0001596A3 (en) | Method for producing 5-aminomethyl-2-chloropyridines | |
| HUP0003768A3 (en) | Method for producing thiochloroformates | |
| HUP0004658A3 (en) | Method for preparing 1-phenylpyrazolin-3-carboxylic acid derivatives | |
| IL132968A0 (en) | Method for producing 2-cyclododecyl-1-propanol | |
| IL136698A0 (en) | Method for producing chlorobenzoxazolene | |
| EG21405A (en) | Method for preparing phosphorique acid | |
| IL150954A (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
| HK1058030A1 (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
| SI1023279T1 (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
| ZA983777B (en) | Method for preparing formylphosphonic acid | |
| SI1032557T1 (en) | Method for preparing bromomethyl-biphenyl derivatives | |
| HUP9903883A3 (en) | Method for preparing trimethylbenzoquinone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC4A | Lapse of provisional application due to refusal |