AR012946A1 - Forma cristalina a de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida, preparaciones farmaceuticas que los contienen y su uso para la preparacion de medicamentos - Google Patents

Forma cristalina a de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida, preparaciones farmaceuticas que los contienen y su uso para la preparacion de medicamentos

Info

Publication number
AR012946A1
AR012946A1 ARP980102708A ARP980102708A AR012946A1 AR 012946 A1 AR012946 A1 AR 012946A1 AR P980102708 A ARP980102708 A AR P980102708A AR P980102708 A ARP980102708 A AR P980102708A AR 012946 A1 AR012946 A1 AR 012946A1
Authority
AR
Argentina
Prior art keywords
carboxamide
pharmaceutical preparations
preparation
modification
preparations containing
Prior art date
Application number
ARP980102708A
Other languages
English (en)
Spanish (es)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4209650&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR012946(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR012946A1 publication Critical patent/AR012946A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP980102708A 1997-06-10 1998-06-09 Forma cristalina a de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida, preparaciones farmaceuticas que los contienen y su uso para la preparacion de medicamentos AR012946A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH140497 1997-06-10

Publications (1)

Publication Number Publication Date
AR012946A1 true AR012946A1 (es) 2000-11-22

Family

ID=4209650

Family Applications (4)

Application Number Title Priority Date Filing Date
ARP980102708A AR012946A1 (es) 1997-06-10 1998-06-09 Forma cristalina a de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida, preparaciones farmaceuticas que los contienen y su uso para la preparacion de medicamentos
ARP980102707A AR012945A1 (es) 1997-06-10 1998-06-09 Formas cristalinas b y c del compuesto 1-(2,6-difluorbencil)-1h-1,2,3- triazol-4 carboxamida, un preparado farmaceutico y uso para la obtenciondel mismo y para la manufactura de un medicamento
ARP070102132A AR061005A2 (es) 1997-06-10 2007-05-17 Forma cristalina a de 1-(2,6- difluorobencil)-1h-1,2,3- triazol-4-carboxamida, preparaciones farmaceuticas que las contienen y su uso para la preparacion de medicamentos
ARP070102131A AR061004A2 (es) 1997-06-10 2007-05-17 Formas cristalinas b y c del compuesto 1-(2,6-difluorobencil)-1h-1,2,3-triazol-4- carboxamida, un preparado farmaceutico y uso para la obtencion del mismo y para la manufactura de un medicamento

Family Applications After (3)

Application Number Title Priority Date Filing Date
ARP980102707A AR012945A1 (es) 1997-06-10 1998-06-09 Formas cristalinas b y c del compuesto 1-(2,6-difluorbencil)-1h-1,2,3- triazol-4 carboxamida, un preparado farmaceutico y uso para la obtenciondel mismo y para la manufactura de un medicamento
ARP070102132A AR061005A2 (es) 1997-06-10 2007-05-17 Forma cristalina a de 1-(2,6- difluorobencil)-1h-1,2,3- triazol-4-carboxamida, preparaciones farmaceuticas que las contienen y su uso para la preparacion de medicamentos
ARP070102131A AR061004A2 (es) 1997-06-10 2007-05-17 Formas cristalinas b y c del compuesto 1-(2,6-difluorobencil)-1h-1,2,3-triazol-4- carboxamida, un preparado farmaceutico y uso para la obtencion del mismo y para la manufactura de un medicamento

Country Status (36)

Country Link
US (6) US6740669B1 (cg-RX-API-DMAC7.html)
EP (2) EP0994863B1 (cg-RX-API-DMAC7.html)
JP (2) JP3672575B2 (cg-RX-API-DMAC7.html)
KR (2) KR100425656B1 (cg-RX-API-DMAC7.html)
CN (3) CN1159300C (cg-RX-API-DMAC7.html)
AR (4) AR012946A1 (cg-RX-API-DMAC7.html)
AT (2) ATE237599T1 (cg-RX-API-DMAC7.html)
AU (2) AU725517B2 (cg-RX-API-DMAC7.html)
BR (2) BR9804947A (cg-RX-API-DMAC7.html)
CA (3) CA2256015C (cg-RX-API-DMAC7.html)
CO (2) CO4940452A1 (cg-RX-API-DMAC7.html)
CY (1) CY2007014I1 (cg-RX-API-DMAC7.html)
CZ (2) CZ292260B6 (cg-RX-API-DMAC7.html)
DE (3) DE69813560T2 (cg-RX-API-DMAC7.html)
DK (2) DK0994863T3 (cg-RX-API-DMAC7.html)
ES (2) ES2192779T3 (cg-RX-API-DMAC7.html)
FR (1) FR07C0037I2 (cg-RX-API-DMAC7.html)
HU (2) HU225153B1 (cg-RX-API-DMAC7.html)
ID (2) ID21014A (cg-RX-API-DMAC7.html)
IL (2) IL125732A (cg-RX-API-DMAC7.html)
LU (1) LU91345I2 (cg-RX-API-DMAC7.html)
MY (2) MY120156A (cg-RX-API-DMAC7.html)
NL (1) NL300284I2 (cg-RX-API-DMAC7.html)
NO (2) NO329315B1 (cg-RX-API-DMAC7.html)
NZ (2) NZ331370A (cg-RX-API-DMAC7.html)
PE (2) PE79799A1 (cg-RX-API-DMAC7.html)
PL (2) PL191943B1 (cg-RX-API-DMAC7.html)
PT (1) PT994864E (cg-RX-API-DMAC7.html)
RU (2) RU2198167C2 (cg-RX-API-DMAC7.html)
SI (2) SI0994864T1 (cg-RX-API-DMAC7.html)
SK (2) SK283734B6 (cg-RX-API-DMAC7.html)
TR (2) TR199801631T1 (cg-RX-API-DMAC7.html)
TW (2) TW403740B (cg-RX-API-DMAC7.html)
UY (1) UY25844A1 (cg-RX-API-DMAC7.html)
WO (2) WO1998056772A1 (cg-RX-API-DMAC7.html)
ZA (2) ZA984967B (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW403740B (en) 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
MXPA04011865A (es) * 2002-05-31 2005-03-31 Schering Corp Polimorfos inhibidores de xantina fosfodiesterasa v.
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US7875284B2 (en) * 2006-03-10 2011-01-25 Cook Incorporated Methods of manufacturing and modifying taxane coatings for implantable medical devices
US20090069390A1 (en) * 2007-09-12 2009-03-12 Protia, Llc Deuterium-enriched rufinamide
NZ591725A (en) * 2008-10-13 2012-09-28 Cipla Ltd PROCESS FOR THE PREPARATION OF RUFINAMIDE which is also known as 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
CN101768124B (zh) * 2008-12-30 2012-01-04 北京本草天源药物研究院 一种药物晶体及其制备方法和用途
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
EP2473051B1 (en) * 2009-09-04 2016-02-10 Tactical Therapeutics, Inc. Novel compositions and processes for preparing 5-amino or substituted amino 1,2,3-triazoles and triazole orotate formulations
EP2465853A1 (en) * 2010-12-14 2012-06-20 Laboratorios Lesvi, S.L. Polymorph of rufinamide and process for obtaining it
EP2727914A1 (en) 2010-04-30 2014-05-07 Laboratorios Lesvi, S.L. Polymorph of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-carboxamide
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014013511A2 (en) * 2012-07-20 2014-01-23 Hetero Research Foundation Rufinamide solid dispersion
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

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US4156734A (en) 1976-02-13 1979-05-29 Merck & Co., Inc. Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
GB1511195A (en) 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
US4536518A (en) 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4346097A (en) * 1980-09-30 1982-08-24 Warner-Lambert Company Method for treating convulsions with pyrazole-4-carboxamide derivatives
FI834666A7 (fi) 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.
US4789680A (en) * 1982-12-23 1988-12-06 Ciba-Geigy Corporation Aralkyltriazole compounds
US4511572A (en) * 1983-03-18 1985-04-16 The University Of Kentucky Research Foundation Triazoline anticonvulsant drugs
PH22568A (en) * 1985-04-18 1988-10-17 Ciba Geigy Ag Fluorinated benzyl triazoles and pharmaceutical compositions containing the same
CA2002864C (en) 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
JPH02214504A (ja) 1989-02-15 1990-08-27 Nissan Chem Ind Ltd 光学活性キノキサリン化合物の晶析法
JPH04506967A (ja) 1989-07-27 1992-12-03 ジー．ディー．サール　アンド　カンパニー 高血圧症治療用腎選択性生成物
IL96507A0 (en) 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
JP2550456B2 (ja) 1990-11-06 1996-11-06 山之内製薬株式会社 縮合ピラジン誘導体
JP2753911B2 (ja) 1991-12-06 1998-05-20 キッセイ薬品工業株式会社 Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法
DE4217952A1 (de) 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
US5248699A (en) 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
US5631373A (en) 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9418443D0 (en) 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
GB9419318D0 (en) 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
CN1072215C (zh) 1995-02-22 2001-10-03 赫彻斯特药品和化学品公司 无定形吡咯他尼、吡咯他尼多晶型物,其制备方法和用途
JP3537147B2 (ja) * 1996-07-11 2004-06-14 ノバルティス アクチエンゲゼルシャフト １―置換４―シアノ―１，２，３―トリアゾールの製造法
TW403740B (en) * 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide

Also Published As

Publication number Publication date
DE122007000051I2 (de) 2009-02-19
IL125733A0 (en) 1999-04-11
DE122007000051I1 (de) 2007-11-08
IL125733A (en) 2002-12-01
CN1298708C (zh) 2007-02-07
PL191943B1 (pl) 2006-07-31
EP0994863A1 (en) 2000-04-26
DE69811500T2 (de) 2004-04-01
NO329315B1 (no) 2010-09-27
HU226107B1 (en) 2008-04-28
HU225153B1 (en) 2006-07-28
JP3672575B2 (ja) 2005-07-20
AR061005A2 (es) 2008-07-30
TR199801631T1 (xx) 1999-06-21
BR9804947A (pt) 1999-08-24
CO4940452A1 (es) 2000-07-24
NO983666L (no) 1998-12-17
HK1028241A1 (en) 2001-02-09
CZ292260B6 (cs) 2003-08-13
CA2256013A1 (en) 1998-12-17
HUP0002113A2 (hu) 2001-02-28
SK109398A3 (en) 1998-12-02
HUP0002113A3 (en) 2002-09-30
US20040167186A1 (en) 2004-08-26
US20060116520A1 (en) 2006-06-01
UY25844A1 (es) 2001-08-27
IL125732A (en) 2002-12-01
ES2197485T3 (es) 2004-01-01
KR19990087835A (ko) 1999-12-27
CZ292481B6 (cs) 2003-09-17
US8076362B2 (en) 2011-12-13
US20030125568A1 (en) 2003-07-03
CN1217716A (zh) 1999-05-26
WO1998056772A1 (en) 1998-12-17
JP2000516259A (ja) 2000-12-05
PL192114B1 (pl) 2006-08-31
EP0994864A1 (en) 2000-04-26
KR19990087836A (ko) 1999-12-27
US20010037029A1 (en) 2001-11-01
CY2007014I2 (el) 2009-11-04
US20100310655A1 (en) 2010-12-09
PE80999A1 (es) 1999-09-06
HUP0000798A3 (en) 2000-10-30
TW526195B (en) 2003-04-01
FR07C0037I2 (cg-RX-API-DMAC7.html) 2008-05-16
SK283685B6 (sk) 2003-12-02
RU2198167C2 (ru) 2003-02-10
JP2000516258A (ja) 2000-12-05
PE79799A1 (es) 1999-09-03
SI0994863T1 (en) 2003-08-31
BR9804946A (pt) 1999-08-24
IL125732A0 (en) 1999-04-11
CZ253498A3 (cs) 1999-04-14
ATE237599T1 (de) 2003-05-15
AU725528B2 (en) 2000-10-12
AU8437198A (en) 1998-12-30
DE69811500D1 (de) 2003-03-27
AR061004A2 (es) 2008-07-30
ZA984967B (en) 1999-01-11
TR199801630T1 (xx) 1999-06-21
NO983666D0 (no) 1998-08-11
KR100425656B1 (ko) 2004-05-17
SI0994864T1 (en) 2003-10-31
CA2614926C (en) 2010-02-09
TW403740B (en) 2000-09-01
KR100409168B1 (ko) 2004-01-31
CN1159300C (zh) 2004-07-28
CA2614926A1 (en) 1998-12-17
ID27660A (id) 2001-04-19
CA2256013C (en) 2007-10-16
AU725517B2 (en) 2000-10-12
PL330798A1 (en) 1999-06-07
HUP0000798A2 (hu) 2000-10-30
NO329314B1 (no) 2010-09-27
FR07C0037I1 (cg-RX-API-DMAC7.html) 2007-08-17
DE69813560T2 (de) 2004-02-05
NZ331370A (en) 2000-08-25
EP0994863B1 (en) 2003-02-19
CZ253398A3 (cs) 1999-04-14
CO4940448A1 (es) 2000-07-24
CN1259127A (zh) 2000-07-05
US6740669B1 (en) 2004-05-25
MY120156A (en) 2005-09-30
MY125854A (en) 2006-08-30
PT994864E (pt) 2003-07-31
ID21014A (id) 1999-04-08
EP0994864B1 (en) 2003-04-16
JP3672574B2 (ja) 2005-07-20
DK0994864T3 (da) 2003-07-21
NL300284I1 (nl) 2007-10-01
NO983667D0 (no) 1998-08-11
SK283734B6 (sk) 2003-12-02
WO1998056773A1 (en) 1998-12-17
LU91345I9 (cg-RX-API-DMAC7.html) 2018-12-31
NO983667L (no) 1998-12-17
LU91345I2 (fr) 2007-09-04
CN1132820C (zh) 2003-12-31
ES2192779T3 (es) 2003-10-16
US7750028B2 (en) 2010-07-06
RU2194041C2 (ru) 2002-12-10
AU8437298A (en) 1998-12-30
CA2256015A1 (en) 1998-12-17
PL330764A1 (en) 1999-05-24
DE69813560D1 (de) 2003-05-22
NZ331371A (en) 2000-08-25
CA2256015C (en) 2008-06-03
SK109498A3 (en) 1998-12-02
US6455556B2 (en) 2002-09-24
HK1028242A1 (en) 2001-02-09
HK1028031A1 (en) 2001-02-02
NL300284I2 (nl) 2007-11-01
ZA984966B (en) 1999-01-11
ATE232852T1 (de) 2003-03-15
AR012945A1 (es) 2000-11-22
DK0994863T3 (da) 2003-05-26
CN1572789A (zh) 2005-02-02
CY2007014I1 (el) 2009-11-04

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