GB1511195A - Triazole derivatives - Google Patents
Triazole derivativesInfo
- Publication number
- GB1511195A GB1511195A GB4311176A GB4311176A GB1511195A GB 1511195 A GB1511195 A GB 1511195A GB 4311176 A GB4311176 A GB 4311176A GB 4311176 A GB4311176 A GB 4311176A GB 1511195 A GB1511195 A GB 1511195A
- Authority
- GB
- United Kingdom
- Prior art keywords
- triazoles
- alkyl
- triazole derivatives
- compounds
- exclusions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1511195 Triazoles and benzotriazoles N- substituted by arylaliphatic groups ICI UNITED STATES Inc 18 Oct 1976 43111/76 Heading C2C The invention provides the title compounds, subject to elaborated definitions and exclusions; IH-triazoles in which the aliphatic part of the substitutent may be interrupted by an oxygen atom, or in which the N-substituent is C 4-6 alkyl or cycloalkyl-alkyl; and 2-(C 6 -alkyl)-2H- triazoles. These compounds have tranquilizing, and (at higher dose levels) sedative activity. Starting materials are also prepared.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4311176A GB1511195A (en) | 1976-10-18 | 1976-10-18 | Triazole derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4311176A GB1511195A (en) | 1976-10-18 | 1976-10-18 | Triazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1511195A true GB1511195A (en) | 1978-05-17 |
Family
ID=10427368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4311176A Expired GB1511195A (en) | 1976-10-18 | 1976-10-18 | Triazole derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1511195A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0151529A2 (en) * | 1984-02-02 | 1985-08-14 | Merck & Co. Inc. | 5-(Amino or substituted amino)-1,2,3-triazoles |
EP0199262A2 (en) * | 1985-04-18 | 1986-10-29 | Ciba-Geigy Ag | Fluorinated benzyl triazole compounds |
US4801594A (en) * | 1984-06-18 | 1989-01-31 | Eli Lilly And Company | Aromatase inhibitors |
US4845227A (en) * | 1984-06-18 | 1989-07-04 | Eli Lilly And Company | Aromatase inhibitors from azoles |
US5227393A (en) * | 1990-12-12 | 1993-07-13 | Ciba-Geigy Corporation | α-fluoro-α-tetrazolyl-phenylmethyl derivatives useful as aromatase inhibitors |
US7750028B2 (en) | 1997-06-10 | 2010-07-06 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1, 2,3-triazole-4-carboxamide |
EP1609505B1 (en) * | 1999-03-01 | 2013-12-11 | Novartis AG | Use of fluorinated triazoles for treating affective or attention disorders |
CN111196785A (en) * | 2020-01-21 | 2020-05-26 | 成都新朝阳作物科学股份有限公司 | Triazole derivative and preparation method and application thereof |
-
1976
- 1976-10-18 GB GB4311176A patent/GB1511195A/en not_active Expired
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4590201A (en) * | 1984-02-02 | 1986-05-20 | Merck & Co., Inc. | 5-amino or substituted amino 1,2,3-triazoles |
EP0151529A2 (en) * | 1984-02-02 | 1985-08-14 | Merck & Co. Inc. | 5-(Amino or substituted amino)-1,2,3-triazoles |
EP0151529A3 (en) * | 1984-02-02 | 1988-04-27 | Merck & Co. Inc. | 5-(amino or substituted amino)-1,2,3-triazoles |
US4801594A (en) * | 1984-06-18 | 1989-01-31 | Eli Lilly And Company | Aromatase inhibitors |
US4845227A (en) * | 1984-06-18 | 1989-07-04 | Eli Lilly And Company | Aromatase inhibitors from azoles |
EP0199262A3 (en) * | 1985-04-18 | 1987-08-26 | Ciba-Geigy Ag | Fluorinated benzyl triazole compounds |
EP0199262A2 (en) * | 1985-04-18 | 1986-10-29 | Ciba-Geigy Ag | Fluorinated benzyl triazole compounds |
AU599024B2 (en) * | 1985-04-18 | 1990-07-12 | Novartis Ag | Fluorinated benzyltriazoles |
US5227393A (en) * | 1990-12-12 | 1993-07-13 | Ciba-Geigy Corporation | α-fluoro-α-tetrazolyl-phenylmethyl derivatives useful as aromatase inhibitors |
US5457209A (en) * | 1990-12-12 | 1995-10-10 | Ciba-Geigy Corporation | 4-[α(cyanophenyl)-1-(1,2,3-triazolyl)methyl]-benzonitrile |
US5637605A (en) * | 1990-12-12 | 1997-06-10 | Ciba Geigy Corporation | α-fluoro-α-1-(1,2,4-triazolyl)-phenylmethyl derivatives useful as aromatase inhibitors |
US7750028B2 (en) | 1997-06-10 | 2010-07-06 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1, 2,3-triazole-4-carboxamide |
US8076362B2 (en) | 1997-06-10 | 2011-12-13 | Novartis Ag | Crystal modification A of 1-(2,6-difluorobenzyI)-1 H-1,2,3-triazole-4-carboxamide and dosage forms and formulations thereof |
EP1609505B1 (en) * | 1999-03-01 | 2013-12-11 | Novartis AG | Use of fluorinated triazoles for treating affective or attention disorders |
CN111196785A (en) * | 2020-01-21 | 2020-05-26 | 成都新朝阳作物科学股份有限公司 | Triazole derivative and preparation method and application thereof |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |