AP858A - Process for preparing solid dosage forms of very low-dose drugs. - Google Patents

Process for preparing solid dosage forms of very low-dose drugs. Download PDF

Info

Publication number
AP858A
AP858A APAP/P/1998/001170A AP9801170A AP858A AP 858 A AP858 A AP 858A AP 9801170 A AP9801170 A AP 9801170A AP 858 A AP858 A AP 858A
Authority
AP
ARIPO
Prior art keywords
composition according
drug
carrier
daily dose
excipient
Prior art date
Application number
APAP/P/1998/001170A
Other languages
English (en)
Other versions
AP9801170A0 (en
Inventor
James Albert Napper
Karen Triona O'brien
Sultan James Manek
Rajinder Kumar
Julia Mary Loudon
Michael Sidney George Clark
Neil Mortimer
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515624.6A external-priority patent/GB9515624D0/en
Priority claimed from GBGB9606684.0A external-priority patent/GB9606684D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AP9801170A0 publication Critical patent/AP9801170A0/xx
Application granted granted Critical
Publication of AP858A publication Critical patent/AP858A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
APAP/P/1998/001170A 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs. AP858A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9515624.6A GB9515624D0 (en) 1995-07-29 1995-07-29 Novel process
GBGB9606684.0A GB9606684D0 (en) 1996-03-29 1996-03-29 Novel process
PCT/EP1996/003326 WO1997004750A2 (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs

Publications (2)

Publication Number Publication Date
AP9801170A0 AP9801170A0 (en) 1998-01-31
AP858A true AP858A (en) 2000-07-12

Family

ID=26307485

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001170A AP858A (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs.

Country Status (25)

Country Link
EP (1) EP0841902A2 (ru)
JP (1) JPH11510493A (ru)
KR (1) KR19990035972A (ru)
CN (1) CN1196677A (ru)
AP (1) AP858A (ru)
AR (1) AR004178A1 (ru)
AU (1) AU716961B2 (ru)
BG (1) BG102266A (ru)
BR (1) BR9609804A (ru)
CA (1) CA2228048A1 (ru)
CZ (1) CZ24798A3 (ru)
DZ (1) DZ2077A1 (ru)
EA (2) EA000740B1 (ru)
HU (1) HUP9900521A3 (ru)
IL (1) IL122897A0 (ru)
MA (1) MA23953A1 (ru)
MX (1) MX9800809A (ru)
NO (1) NO980384L (ru)
NZ (1) NZ315632A (ru)
OA (1) OA10659A (ru)
PL (1) PL325242A1 (ru)
SK (1) SK11098A3 (ru)
TR (1) TR199800156T1 (ru)
UY (1) UY24297A1 (ru)
WO (1) WO1997004750A2 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9619074D0 (en) * 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
CA2323177A1 (en) 1998-03-11 1999-09-16 Susan Marie Milosovich Composition
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
AU2742102A (en) 2000-12-14 2002-06-24 Ortho Mcneil Pharm Inc Steroid hormone products and methods for preparing them
US20070202179A1 (en) * 2004-04-09 2007-08-30 FAULKNER Patrick Low Dose Pharmaceutical Products

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4898736A (en) * 1988-03-09 1990-02-06 Merck & Co., Inc. Method for tablet preparation
EP0392803A1 (en) * 1989-04-13 1990-10-17 Beecham Group p.l.c. Novel compounds
WO1995017168A1 (en) * 1993-12-21 1995-06-29 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS5970614A (ja) * 1982-10-14 1984-04-21 Asahi Chem Ind Co Ltd 微量主薬系湿式固形製剤方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4898736A (en) * 1988-03-09 1990-02-06 Merck & Co., Inc. Method for tablet preparation
EP0392803A1 (en) * 1989-04-13 1990-10-17 Beecham Group p.l.c. Novel compounds
WO1995017168A1 (en) * 1993-12-21 1995-06-29 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products

Also Published As

Publication number Publication date
NO980384D0 (no) 1998-01-28
JPH11510493A (ja) 1999-09-14
AP9801170A0 (en) 1998-01-31
SK11098A3 (en) 1998-07-08
BR9609804A (pt) 1999-07-06
HUP9900521A2 (hu) 1999-06-28
AR004178A1 (es) 1998-11-04
IL122897A0 (en) 1998-08-16
WO1997004750A3 (en) 1997-03-27
EA199800179A1 (ru) 1998-10-29
EP0841902A2 (en) 1998-05-20
EA000740B1 (ru) 2000-02-28
CA2228048A1 (en) 1997-02-13
BG102266A (en) 1998-10-30
NZ315632A (en) 1999-11-29
EA199901055A1 (ru) 2000-06-26
MX9800809A (es) 1998-04-30
WO1997004750A2 (en) 1997-02-13
CN1196677A (zh) 1998-10-21
MA23953A1 (fr) 1997-04-01
AU716961B2 (en) 2000-03-09
TR199800156T1 (xx) 1998-04-21
KR19990035972A (ko) 1999-05-25
NO980384L (no) 1998-03-26
OA10659A (en) 2002-09-18
AU6738496A (en) 1997-02-26
DZ2077A1 (fr) 2002-07-22
PL325242A1 (en) 1998-07-06
HUP9900521A3 (en) 2001-04-28
UY24297A1 (es) 1997-01-23
CZ24798A3 (cs) 1998-06-17

Similar Documents

Publication Publication Date Title
JP4868695B2 (ja) 崩壊性が良好な経口製剤
US5211958A (en) Pharmaceutical composition and process for its preparation
JPH0122245B2 (ru)
CA3019508A1 (en) Oral preparation having exceptional elutability
AU748396B2 (en) Composition
US20030129246A1 (en) Process for preparing solid dosage forms of very low-dose drugs
EP0862421B1 (en) Prompt-release pharmaceutical compositions
EP3749286A1 (en) A pharmaceutical composition comprising metamizole, drotaverine, and caffeine
AP858A (en) Process for preparing solid dosage forms of very low-dose drugs.
TWI426913B (zh) 提昇水懸浮性之細粒劑
SK50132006A3 (sk) Flukonazolové kapsuly so zlepšeným uvoľňovaním
MXPA98000809A (en) Procedure to prepare forms of solid doses of very low dose of farm
CA1334933C (en) Pharmaceutical composition and process for its preparation
JP2012140410A (ja) ロキソプロフェンナトリウム及びトラネキサム酸を含有する固形製剤
CZ2002179A3 (cs) Tablety obsahující nízkou dávku účinné látky, prostředek a způsob přípravy tablety
AU751607B2 (en) Method of treatment of dementia
AU2014295098B2 (en) Anti-tuberculosis stable pharmaceutical composition in a form of a coated tablet comprising granules of isoniazid and granules of rifapentine and its process of preparation
KR101938872B1 (ko) 도네페질 또는 그의 약학적으로 허용 가능한 염 및 메만틴 또는 그의 약학적으로 허용 가능한 염을 함유하는 치매 및 인지기능 장애 예방 또는 치료용 약학 조성물 및 이의 제조방법
EA002428B1 (ru) Стабильные композиции, содержащие левозимендан и альгиновую кислоту
JP2000239185A (ja) 医薬組成物
JPH08325142A (ja) ヨウ化イソプロパミド含有製剤
JP2005529929A (ja) プロゲスターゲン投与単位
TR202014200A2 (tr) Soğuk alginliği tedavi̇si̇ i̇çi̇n i̇buprofen, psödoefedri̇n ve askorbi̇k asi̇t i̇çeren farmasöti̇k bi̇leşi̇mler
JP2019006733A (ja) エゼチミブ含有経口製剤及びその製造方法
SK15612000A3 (sk) Perorálne tablety s riadeným uvoľňovaním farmaceuticky akceptovateľných solí metoprololu a spôsob ich prípravy