AP666A - Valaciclovir tablets containing colloidal silicon dioxide. - Google Patents

Valaciclovir tablets containing colloidal silicon dioxide. Download PDF

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Publication number
AP666A
AP666A APAP/P/1997/001057A AP9701057A AP666A AP 666 A AP666 A AP 666A AP 9701057 A AP9701057 A AP 9701057A AP 666 A AP666 A AP 666A
Authority
AP
ARIPO
Prior art keywords
tablet
valaciclovir
lubricant
silicon dioxide
present
Prior art date
Application number
APAP/P/1997/001057A
Other languages
English (en)
Other versions
AP9701057A0 (en
Inventor
Carter Barry Howard
Tillman Lloyd Gary
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10768317&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP666(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of AP9701057A0 publication Critical patent/AP9701057A0/xx
Application granted granted Critical
Publication of AP666A publication Critical patent/AP666A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
APAP/P/1997/001057A 1995-01-20 1996-01-19 Valaciclovir tablets containing colloidal silicon dioxide. AP666A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9501127.6A GB9501127D0 (en) 1995-01-20 1995-01-20 Tablet
PCT/GB1996/000111 WO1996022082A1 (en) 1995-01-20 1996-01-19 Valaciclovir tablets containing colloidal silicon dioxide

Publications (2)

Publication Number Publication Date
AP9701057A0 AP9701057A0 (en) 1997-10-31
AP666A true AP666A (en) 1998-08-24

Family

ID=10768317

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/001057A AP666A (en) 1995-01-20 1996-01-19 Valaciclovir tablets containing colloidal silicon dioxide.

Country Status (39)

Country Link
US (1) US5879706A (zh)
EP (1) EP0806943B1 (zh)
JP (1) JP3350055B2 (zh)
KR (1) KR100412298B1 (zh)
CN (2) CN1131026C (zh)
AP (1) AP666A (zh)
AT (1) ATE190483T1 (zh)
AU (1) AU710823B2 (zh)
BG (1) BG63187B1 (zh)
BR (1) BR9606769A (zh)
CA (1) CA2210891C (zh)
CY (1) CY2182B1 (zh)
CZ (1) CZ296514B6 (zh)
DE (1) DE69607146T2 (zh)
DK (1) DK0806943T3 (zh)
EA (1) EA000276B1 (zh)
EE (1) EE03336B1 (zh)
ES (1) ES2145425T3 (zh)
FI (1) FI119722B (zh)
GB (1) GB9501127D0 (zh)
GE (1) GEP20022752B (zh)
GR (1) GR3033677T3 (zh)
HK (1) HK1002851A1 (zh)
HU (1) HU226131B1 (zh)
IL (1) IL116830A (zh)
IN (1) IN181318B (zh)
MY (1) MY126346A (zh)
NO (1) NO311488B1 (zh)
NZ (1) NZ298846A (zh)
OA (1) OA10500A (zh)
PL (1) PL185307B1 (zh)
PT (1) PT806943E (zh)
RO (1) RO118175B1 (zh)
SK (1) SK282030B6 (zh)
TR (1) TR199700657T1 (zh)
UA (1) UA68325C2 (zh)
UY (2) UY25774A1 (zh)
WO (1) WO1996022082A1 (zh)
ZA (1) ZA96448B (zh)

Families Citing this family (44)

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GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
PT874631E (pt) * 1996-01-19 2004-04-30 Glaxo Group Ltd Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
KR20010101295A (ko) * 1998-12-18 2001-11-14 스티븐 에프. 웨인스톡 디발프로엑스 나트륨의 조절-방출성 제형물
GB0010446D0 (en) * 2000-04-28 2000-06-14 Glaxo Wellcome Kk Pharmaceutical formulation
DE60221238T2 (de) * 2001-05-01 2007-10-31 Pfizer Products Inc., Groton Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung
US7815936B2 (en) * 2001-10-30 2010-10-19 Evonik Degussa Gmbh Use of granular materials based on pyrogenically produced silicon dioxide in pharmaceutical compositions
US20040197396A1 (en) * 2001-11-05 2004-10-07 Fain Helen S Anhydrous crystal form of valaciclovir hydrochloride
KR20050044449A (ko) * 2001-11-14 2005-05-12 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르의 합성 및 정제 방법
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
EP1517678A2 (en) * 2002-06-24 2005-03-30 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050051922A1 (en) * 2002-09-20 2005-03-10 Avinash Nangia Pharmaceutical composition with sodium lauryl sulfate as an extra-granular absorption/compression enhancer and the process to make the same
DE60307494D1 (de) * 2002-10-16 2006-09-21 Teva Pharma Verfahren zur verminderung von restalkoholen im kristallinen valacyclovir-hydrochlorid
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
AU2003232719A1 (en) * 2003-05-30 2005-01-21 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Novel crystalline forms of valacyclovir hydrochloride
EP2014660A3 (en) * 2003-06-02 2009-07-15 Teva Pharmaceutical Industries Ltd Novel crystalline forms of valacyclovir hydrochloride
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
DK3260117T3 (da) 2003-09-12 2019-07-01 Amgen Inc Hurtigt opløsende formulering, der omfatter cinacalcet-hcl
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
ES2246034T3 (es) * 2003-12-09 2006-02-01 Helm Ag Formulacion farmaceutica de valaciclovir.
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
KR101116747B1 (ko) 2004-12-06 2012-02-22 에스케이케미칼주식회사 안정성이 개선된 말레인산 암로디핀 약제 조성물
CN101132779B (zh) 2005-03-07 2016-03-16 拜尔健康护理有限责任公司 用于治疗癌症的包含ω-羧芳基取代的二苯基脲的药物组合物
WO2006127217A2 (en) * 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
WO2007090595A1 (en) * 2006-02-06 2007-08-16 Fidia Pharmaceutici S.P.A. Solid formulations of valacyclovir hydrochloride
EP2023899A1 (en) * 2006-05-10 2009-02-18 Evonik Degussa GmbH Use of roll compacted pyrogenically produced silicon dioxide in pharmaceutical compositions
ATE481089T1 (de) * 2006-05-31 2010-10-15 Vertex Pharma Orale formulierungen mit kontrollierter freisetzung eines interleukin-1-beta-converting- enzyme inhibitors
WO2008006534A2 (en) * 2006-07-11 2008-01-17 Lek Pharmaceuticals D.D. Multiple unit tablets
US20080167325A1 (en) * 2006-12-27 2008-07-10 Bs Praveen Kumar Valacyclovir compositions
US20090076039A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched valacyclovir
ITRM20080027A1 (it) * 2008-01-18 2009-07-19 Maria Balestrieri Uso di aciclovir per il trattamento delle condilomatosi.
US20100124560A1 (en) * 2008-11-14 2010-05-20 Mcneil Ab Multi portion intra-oral dosage form and use thereof
JP5583659B2 (ja) * 2009-03-13 2014-09-03 富山化学工業株式会社 ６−フルオロ−３−ヒドロキシ−２−ピラジンカルボキサミド含有錠剤および造粒末
CH703348A1 (de) * 2010-06-29 2011-12-30 Mepha Gmbh Zusammensetzungen mit hohem Wirkstoffanteil an pharmazeutisch aktiven Substanzen.
GB2515486A (en) * 2013-06-24 2014-12-31 Kraft Foods R & D Inc Soluble Beverage Ingredients
KR101497508B1 (ko) * 2013-12-20 2015-03-03 한국유나이티드제약 주식회사 펠라고니움 시도이데스 추출물 및 규산 화합물을 포함하는 고형 제제 및 이의 제조 방법
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
WO2020049536A1 (en) * 2018-09-07 2020-03-12 Jubilant Generics Limited Pharmaceutical compositions of valacyclovir or its pharmaceutically acceptable salts thereof
CN110279667B (zh) * 2019-07-30 2023-02-10 珠海润都制药股份有限公司 一种盐酸伐昔洛韦片及其制备方法
US20240173259A1 (en) * 2020-12-01 2024-05-30 Lg Chem, Ltd. Oral formulation comprising 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid and method for preparing same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0308065A2 (en) * 1987-08-15 1989-03-22 The Wellcome Foundation Limited Therapeutic nucleosides

Family Cites Families (6)

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CA1259924A (en) * 1985-03-25 1989-09-26 Wallace E. Becker Pharmaceutical tableting method
ES2052911T3 (es) * 1988-05-04 1994-07-16 Smith Kline French Lab Tableta masticable.
MY110880A (en) * 1991-01-30 1999-06-30 The Wellcome Foundation Ltd Water-dispersible tablets
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0308065A2 (en) * 1987-08-15 1989-03-22 The Wellcome Foundation Limited Therapeutic nucleosides

Also Published As

Publication number Publication date
GEP20022752B (en) 2002-08-26
HK1002851A1 (en) 1998-09-25
FI973062A0 (fi) 1997-07-18
WO1996022082A1 (en) 1996-07-25
AU710823B2 (en) 1999-09-30
ZA96448B (en) 1996-08-07
CZ229297A3 (cs) 1998-02-18
OA10500A (en) 2002-04-10
HUP9801872A2 (hu) 1999-10-28
RO118175B1 (ro) 2003-03-28
HU226131B1 (en) 2008-05-28
UA68325C2 (en) 2004-08-16
GR3033677T3 (en) 2000-10-31
JPH10512564A (ja) 1998-12-02
DK0806943T3 (da) 2000-07-24
EP0806943B1 (en) 2000-03-15
NZ298846A (en) 1998-06-26
JP3350055B2 (ja) 2002-11-25
SK96497A3 (en) 1998-01-14
PL321361A1 (en) 1997-12-08
BR9606769A (pt) 1997-12-30
EE03336B1 (et) 2001-02-15
EA199700123A1 (ru) 1997-12-30
KR19980701524A (ko) 1998-05-15
CY2182B1 (en) 2002-08-23
CZ296514B6 (cs) 2006-03-15
DE69607146T2 (de) 2000-09-21
AU4453496A (en) 1996-08-07
FI119722B (fi) 2009-02-27
IL116830A0 (en) 1996-05-14
US5879706A (en) 1999-03-09
IL116830A (en) 2000-02-29
AP9701057A0 (en) 1997-10-31
TR199700657T1 (xx) 1998-02-21
HUP9801872A3 (en) 2001-02-28
EA000276B1 (ru) 1999-02-25
DE69607146D1 (de) 2000-04-20
MX9705459A (es) 1997-10-31
CN1313081C (zh) 2007-05-02
MY126346A (en) 2006-09-29
KR100412298B1 (ko) 2004-04-21
PT806943E (pt) 2000-08-31
NO973327L (no) 1997-09-16
FI973062A (fi) 1997-09-18
CA2210891A1 (en) 1996-07-25
CN1131026C (zh) 2003-12-17
BG101831A (en) 1998-04-30
BG63187B1 (bg) 2001-06-29
IN181318B (zh) 1998-05-09
CA2210891C (en) 2009-05-19
UY25778A1 (es) 2000-08-21
EP0806943A1 (en) 1997-11-19
CN1494898A (zh) 2004-05-12
GB9501127D0 (en) 1995-03-08
UY25774A1 (es) 2000-10-31
PL185307B1 (pl) 2003-04-30
NO311488B1 (no) 2001-12-03
ES2145425T3 (es) 2000-07-01
SK282030B6 (sk) 2001-10-08
ATE190483T1 (de) 2000-04-15
CN1179100A (zh) 1998-04-15
NO973327D0 (no) 1997-07-18

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