ZW12380A1 - Novel 3-vinyl-cephalosporins and their preparation - Google Patents

Novel 3-vinyl-cephalosporins and their preparation

Info

Publication number
ZW12380A1
ZW12380A1 ZW123/80A ZW12380A ZW12380A1 ZW 12380 A1 ZW12380 A1 ZW 12380A1 ZW 123/80 A ZW123/80 A ZW 123/80A ZW 12380 A ZW12380 A ZW 12380A ZW 12380 A1 ZW12380 A1 ZW 12380A1
Authority
ZW
Zimbabwe
Prior art keywords
cephalosporins
vinyl
novel
preparation
Prior art date
Application number
ZW123/80A
Other languages
English (en)
Inventor
Roy Pierre Le
Daniel Farge
Jean Francois Peyronel
Claude Moutonnier
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of ZW12380A1 publication Critical patent/ZW12380A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZW123/80A 1979-05-23 1980-05-21 Novel 3-vinyl-cephalosporins and their preparation ZW12380A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7913097A FR2457297A1 (fr) 1979-05-23 1979-05-23 Nouvelles vinyl-3 cephalosporines, et leur preparation

Publications (1)

Publication Number Publication Date
ZW12380A1 true ZW12380A1 (en) 1980-11-26

Family

ID=9225763

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW123/80A ZW12380A1 (en) 1979-05-23 1980-05-21 Novel 3-vinyl-cephalosporins and their preparation

Country Status (32)

Country Link
US (2) US4307230A (xx)
JP (2) JPS55154978A (xx)
AT (2) AT368509B (xx)
AU (2) AU532884B2 (xx)
BE (2) BE883417A (xx)
CA (2) CA1149375A (xx)
CH (2) CH645380A5 (xx)
CS (1) CS235508B2 (xx)
DD (2) DD151169A5 (xx)
DE (2) DE3019430A1 (xx)
DK (2) DK223180A (xx)
ES (4) ES8203906A1 (xx)
FI (2) FI801643A (xx)
FR (1) FR2457297A1 (xx)
GB (2) GB2051061B (xx)
GR (2) GR68428B (xx)
HU (2) HU183143B (xx)
IE (2) IE49812B1 (xx)
IL (2) IL60141A (xx)
IT (2) IT1140972B (xx)
LU (2) LU82476A1 (xx)
NL (2) NL8003010A (xx)
NO (2) NO801504L (xx)
NZ (2) NZ193801A (xx)
PH (2) PH17310A (xx)
PL (3) PL126671B1 (xx)
PT (2) PT71278A (xx)
SE (2) SE8003822L (xx)
SU (4) SU965358A3 (xx)
YU (3) YU136980A (xx)
ZA (2) ZA803035B (xx)
ZW (1) ZW12380A1 (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2494276A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
FR2511376A1 (fr) * 1981-08-17 1983-02-18 Rhone Poulenc Sante Nouveaux derives de la cephalosporine et leur prepration
FR2511372A1 (fr) * 1981-08-17 1983-02-18 Rhone Poulenc Sante Nouveaux derives de la cephalosporine et leur preparation
FR2531712A1 (fr) * 1982-08-13 1984-02-17 Rhone Poulenc Sante Nouveaux derives de la cephalosporine et leur preparation
US4609730A (en) * 1982-11-22 1986-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[substituted imino-2-(2-aminothiazol-4-yl)-acetamido]-3(2,2-dihalovinyl or ethynyl)-3-cephem-4-carboxylic acid (syn isomers), having antimicrobial activities
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
ZA84584B (en) * 1983-01-28 1984-09-26 Bristol Myers Co Substituted vinyl cephalosporins
JPS604883U (ja) * 1983-06-24 1985-01-14 松下冷機株式会社 冷蔵庫等の冷却装置
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
US6025352A (en) * 1997-09-29 2000-02-15 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6030965A (en) * 1997-09-30 2000-02-29 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
WO2003072582A1 (en) * 2002-02-28 2003-09-04 Lg Life Sciences Ltd. Novel cephalosporin compounds and process for preparing the same
US8883772B2 (en) 2007-10-09 2014-11-11 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
ES2700575T3 (es) 2013-03-12 2019-02-18 Gladius Pharmaceuticals Corp 3-Estiril-cefalosporinas derivadas

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US3823139A (en) * 1970-03-26 1974-07-09 Glaxo Lab Ltd Cephalosporins having a ypsilon-carbonyl group at position-3
US3674784A (en) * 1970-07-27 1972-07-04 Lilly Co Eli 3-formyl cephalosporin sulfoxides
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
US4144393A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
DE2637176A1 (de) * 1975-08-22 1977-03-03 Ciba Geigy Ag Carbonylmethylderivate
JPS5285185A (en) * 1976-01-05 1977-07-15 Teijin Ltd Preparation of 7-acylaminocephalosporanic acids
JPS5289694A (en) * 1976-01-23 1977-07-27 Asahi Chem Ind Co Ltd Novel cephalosporins
US4094978A (en) * 1976-07-29 1978-06-13 Syntex (U.S.A.) Inc. 3-propenyl derivatives of cephalosporin, compositions and their use
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
EP0015240A1 (de) * 1979-02-16 1980-09-03 Ciba-Geigy Ag Azacyclyl (thio) ureidoacetyl-Verbindungen und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
CS235508B2 (en) 1985-05-15
NO801503L (no) 1980-11-24
DE3019430A1 (de) 1980-12-04
IE801060L (en) 1980-11-23
ES495237A0 (es) 1981-09-01
SU965358A3 (ru) 1982-10-07
IT8022242A0 (it) 1980-05-21
ES491688A0 (es) 1980-12-16
IT8022241A0 (it) 1980-05-21
PL126491B1 (en) 1983-08-31
AT368509B (de) 1982-10-25
JPS55154978A (en) 1980-12-02
US4365062A (en) 1982-12-21
DD151064A5 (de) 1981-09-30
AU537785B2 (en) 1984-07-12
GB2052488B (en) 1983-09-21
BE883417A (fr) 1980-11-21
ZA803035B (en) 1981-05-27
IT1140972B (it) 1986-10-10
PH15916A (en) 1983-04-22
IL60140A0 (en) 1980-07-31
HU184759B (en) 1984-10-29
PH17310A (en) 1984-07-18
GR68428B (xx) 1981-12-30
YU137080A (en) 1983-04-30
GR68436B (xx) 1981-12-30
IL60141A0 (en) 1980-07-31
FI801642A (fi) 1980-11-24
CA1149375A (fr) 1983-07-05
CA1148141A (fr) 1983-06-14
NO801504L (no) 1980-11-24
SE8003823L (sv) 1980-11-24
AU5859380A (en) 1980-11-27
IT1140973B (it) 1986-10-10
SU927118A3 (ru) 1982-05-07
YU56183A (en) 1984-02-29
PL122638B1 (en) 1982-08-31
PL224392A1 (xx) 1981-02-13
GB2052488A (en) 1981-01-28
SE8003822L (sv) 1980-11-24
NL8003024A (nl) 1980-11-25
ES8106533A1 (es) 1981-08-16
ES491689A0 (es) 1982-04-16
JPS55154979A (en) 1980-12-02
IL60140A (en) 1984-04-30
NL8003010A (nl) 1980-11-25
PT71278A (fr) 1980-06-01
ES495236A0 (es) 1981-08-16
GB2051061B (en) 1983-09-28
GB2051061A (en) 1981-01-14
ES8203906A1 (es) 1982-04-16
NZ193801A (en) 1983-03-15
ES8106734A1 (es) 1981-09-01
IE49813B1 (en) 1985-12-25
DK222280A (da) 1980-11-24
FR2457297B1 (xx) 1982-10-22
PT71277A (fr) 1980-06-01
ZA803036B (en) 1981-05-27
HU183143B (en) 1984-04-28
CH650000A5 (fr) 1985-06-28
FR2457297A1 (fr) 1980-12-19
DD151169A5 (de) 1981-10-08
IL60141A (en) 1984-04-30
ES8102137A1 (es) 1980-12-16
FI801643A (fi) 1980-11-24
SU984411A3 (ru) 1982-12-23
SU988193A3 (ru) 1983-01-07
PL224390A1 (xx) 1981-02-13
LU82478A1 (fr) 1980-12-16
DE3019445A1 (de) 1980-12-04
AT370737B (de) 1983-04-25
AU532884B2 (en) 1983-10-20
YU136980A (en) 1983-10-31
ATA271180A (de) 1982-09-15
BE883418A (fr) 1980-11-21
US4307230A (en) 1981-12-22
PL126671B1 (en) 1983-08-31
AU5859480A (en) 1980-11-27
IE801059L (en) 1980-11-23
ATA271080A (de) 1982-02-15
NZ193800A (en) 1983-05-10
LU82476A1 (fr) 1980-12-16
CH645380A5 (fr) 1984-09-28
DK223180A (da) 1980-11-24
IE49812B1 (en) 1985-12-25

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