ZA985392B - New derivatives of 2-(iminomethyl) amino-phenyl, their preparation their use as medicaments and the pharmaceutical compositions containing them - Google Patents

New derivatives of 2-(iminomethyl) amino-phenyl, their preparation their use as medicaments and the pharmaceutical compositions containing them

Info

Publication number
ZA985392B
ZA985392B ZA985392A ZA985392A ZA985392B ZA 985392 B ZA985392 B ZA 985392B ZA 985392 A ZA985392 A ZA 985392A ZA 985392 A ZA985392 A ZA 985392A ZA 985392 B ZA985392 B ZA 985392B
Authority
ZA
South Africa
Prior art keywords
iminomethyl
medicaments
phenyl
amino
preparation
Prior art date
Application number
ZA985392A
Other languages
English (en)
Inventor
Jeremiah Harnett
Dennis Bigg
De Lassauniere Pierre Chabrier
Serge Auvin
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ZA985392B publication Critical patent/ZA985392B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D521/00Heterocyclic compounds containing unspecified hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA985392A 1997-06-20 1998-06-19 New derivatives of 2-(iminomethyl) amino-phenyl, their preparation their use as medicaments and the pharmaceutical compositions containing them ZA985392B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9707701A FR2764889B1 (fr) 1997-06-20 1997-06-20 Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ZA985392B true ZA985392B (en) 1999-01-20

Family

ID=9508226

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985392A ZA985392B (en) 1997-06-20 1998-06-19 New derivatives of 2-(iminomethyl) amino-phenyl, their preparation their use as medicaments and the pharmaceutical compositions containing them

Country Status (29)

Country Link
EP (1) EP0991654B1 (pl)
JP (1) JP2002507965A (pl)
KR (2) KR100545946B1 (pl)
CN (1) CN1195762C (pl)
AR (1) AR012250A1 (pl)
AT (1) ATE297935T1 (pl)
AU (1) AU737964B2 (pl)
BR (1) BR9810197B1 (pl)
CA (1) CA2294809C (pl)
CZ (1) CZ299237B6 (pl)
DE (1) DE69830584T2 (pl)
DK (1) DK0991654T3 (pl)
ES (1) ES2244068T3 (pl)
FR (1) FR2764889B1 (pl)
HK (1) HK1030218A1 (pl)
HU (1) HUP0002425A3 (pl)
IL (1) IL133223A (pl)
MY (1) MY123193A (pl)
NO (1) NO315321B1 (pl)
NZ (1) NZ501656A (pl)
PL (1) PL191987B1 (pl)
PT (1) PT991654E (pl)
RU (1) RU2202543C2 (pl)
SK (1) SK286911B6 (pl)
TR (1) TR199903175T2 (pl)
TW (1) TW422842B (pl)
UA (1) UA70921C2 (pl)
WO (1) WO1998058934A1 (pl)
ZA (1) ZA985392B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
AR019190A1 (es) * 1998-07-08 2001-12-26 Sod Conseils Rech Applic Derivados de 2-aminopiridinas, productos intermedios para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y su uso para preparar medicamentos
AU5194999A (en) * 1998-08-07 2000-02-28 Takeda Chemical Industries Ltd. Benzothiepin derivatives, process for the preparation of the same and uses thereof
FR2783519B1 (fr) * 1998-09-23 2003-01-24 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
FR2798127A1 (fr) 1999-09-03 2001-03-09 Expansia Sa Nouveau procede de preparation d'amidines derivees de l'acide 6-hydroxy-2,5,7,8-tetramethylchrommane-2-carboxy- lique
FR2812546B1 (fr) * 2000-08-01 2008-11-21 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
RU2380362C2 (ru) * 1999-10-11 2010-01-27 Сосьете Де Консей Де Решерш З Производные пятичленных гетероциклов, способ их получения и их применение в качестве лекарственных средств
TWI292316B (en) * 1999-10-11 2008-01-11 Sod Conseils Rech Applic Pharmaceutical composition of thiazole derivatives intended to inhibit mao and/or lipidic peroxidation and/or to act as modulators of sodium channels and the use thereof
FR2799461B1 (fr) * 1999-10-11 2002-01-04 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
FR2801053B1 (fr) * 1999-11-16 2004-06-25 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments
SE9904677D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
SE9904676D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
AU2001282829A1 (en) * 2000-09-05 2002-03-22 Astrazeneca Ab Amidine derivatives which are inhibitors of nitric oxide synthase
TWI248438B (en) * 2001-04-10 2006-02-01 Sod Conseils Rech Applic Derivatives of heterocycles with 5 members, their preparation and their use as medicaments
JP4410553B2 (ja) 2001-06-08 2010-02-03 サイトカイン・ファーマサイエンシズ・インコーポレーテッド Mifアンタゴニスト活性を有するイソオキサゾリン化合物
HU228783B1 (en) * 2001-07-26 2013-05-28 Greenearth Cleaning Dry cleaning apparatus and method capable of utilizing a siloxane solvent
FR2842808B1 (fr) 2002-07-25 2004-09-10 Sod Conseils Rech Applic Nouveaux derives d'arylimidazoles, leur preparation et leurs applications therapeutiques
DE10233817A1 (de) * 2002-07-25 2004-02-12 Aventis Pharma Deutschland Gmbh Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7141561B2 (en) 2002-07-25 2006-11-28 Sanofi-Aventis Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments
AU2005228417A1 (en) * 2004-03-26 2005-10-13 Cytokine Pharmasciences, Inc. Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
WO2006022442A1 (ja) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. ジヒドロオロテートデヒドロゲナーゼ阻害活性を有する新規複素環アミド誘導体
ES2552108T3 (es) 2005-03-11 2015-11-25 Howard Florey Institute Pty Ltd Compuestos flavonoides y usos de los mismos
BR112012004919A2 (pt) 2009-09-04 2019-09-24 Univ Vanderbilt potencializadores alostericos de mglur4, composição e metodos de tratamentos de disfunção neurologica
WO2011058766A1 (en) * 2009-11-16 2011-05-19 Raqualia Pharma Inc. Aryl carboxamide derivatives as ttx-s blockers
EP2872497B2 (en) * 2012-07-12 2019-10-09 Khondrion Ip B.V. Chromanyl derivatives for treating mitochondrial disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
CA2169280A1 (en) * 1993-08-12 1995-02-23 Robert James Gentile Amidine derivatives with nitric oxide synthetase activities
ATE182889T1 (de) * 1994-05-07 1999-08-15 Astra Ab Bicyclische amidinderivate als no-synthetase inhibitoren

Also Published As

Publication number Publication date
TW422842B (en) 2001-02-21
DE69830584D1 (de) 2005-07-21
CA2294809C (fr) 2010-02-02
ATE297935T1 (de) 2005-07-15
HK1030218A1 (en) 2001-04-27
HUP0002425A3 (en) 2001-12-28
PL191987B1 (pl) 2006-07-31
CN1195762C (zh) 2005-04-06
SK179699A3 (en) 2000-05-16
KR20050098970A (ko) 2005-10-12
CN1264385A (zh) 2000-08-23
MY123193A (en) 2006-05-31
RU2202543C2 (ru) 2003-04-20
HUP0002425A1 (hu) 2001-11-28
NO996208L (no) 2000-02-15
BR9810197A (pt) 2000-08-08
AU737964B2 (en) 2001-09-06
EP0991654B1 (fr) 2005-06-15
FR2764889B1 (fr) 2000-09-01
KR100618478B1 (ko) 2006-09-01
ES2244068T3 (es) 2005-12-01
CZ299237B6 (cs) 2008-05-28
DK0991654T3 (da) 2005-10-17
NO315321B1 (no) 2003-08-18
NO996208D0 (no) 1999-12-15
IL133223A (en) 2004-09-27
JP2002507965A (ja) 2002-03-12
PT991654E (pt) 2005-10-31
KR20010013983A (ko) 2001-02-26
WO1998058934A1 (fr) 1998-12-30
KR100545946B1 (ko) 2006-01-26
CZ459799A3 (cs) 2000-07-12
CA2294809A1 (fr) 1998-12-30
EP0991654A1 (fr) 2000-04-12
TR199903175T2 (xx) 2000-04-21
FR2764889A1 (fr) 1998-12-24
DE69830584T2 (de) 2006-03-16
UA70921C2 (uk) 2004-11-15
BR9810197B1 (pt) 2010-02-09
NZ501656A (en) 2001-12-21
AR012250A1 (es) 2000-09-27
SK286911B6 (sk) 2009-07-06
PL337499A1 (en) 2000-08-28
IL133223A0 (en) 2001-03-19
AU8218998A (en) 1999-01-04

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