UA70921C2 - Похідні 2-(імінометил)амінофенілу, спосіб їх одержання (варіанти) та фармацевтична композиція, що містить ці сполуки - Google Patents

Похідні 2-(імінометил)амінофенілу, спосіб їх одержання (варіанти) та фармацевтична композиція, що містить ці сполуки

Info

Publication number
UA70921C2
UA70921C2 UA99126913A UA99126913A UA70921C2 UA 70921 C2 UA70921 C2 UA 70921C2 UA 99126913 A UA99126913 A UA 99126913A UA 99126913 A UA99126913 A UA 99126913A UA 70921 C2 UA70921 C2 UA 70921C2
Authority
UA
Ukraine
Prior art keywords
iminomethyl
preparation
application
compositions containing
medicaments
Prior art date
Application number
UA99126913A
Other languages
English (en)
Russian (ru)
Inventor
Серж Овен
Джеремі Арнетт
Денніс Бігг
де Лассон'єр П'єр-Етьєн Шабріе
Original Assignee
Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) filed Critical Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.)
Publication of UA70921C2 publication Critical patent/UA70921C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D521/00—Heterocyclic compounds containing unspecified hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Даний винахід стосується нових похідних 2-(імінометил)амінофенілу , їх одержання, застосування як ліків та фармацевтичних композицій, що містять ці сполуки.
UA99126913A 1997-06-20 1998-06-15 Похідні 2-(імінометил)амінофенілу, спосіб їх одержання (варіанти) та фармацевтична композиція, що містить ці сполуки UA70921C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9707701A FR2764889B1 (fr) 1997-06-20 1997-06-20 Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
PCT/FR1998/001250 WO1998058934A1 (fr) 1997-06-20 1998-06-15 Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
UA70921C2 true UA70921C2 (uk) 2004-11-15

Family

ID=9508226

Family Applications (1)

Application Number Title Priority Date Filing Date
UA99126913A UA70921C2 (uk) 1997-06-20 1998-06-15 Похідні 2-(імінометил)амінофенілу, спосіб їх одержання (варіанти) та фармацевтична композиція, що містить ці сполуки

Country Status (29)

Country Link
EP (1) EP0991654B1 (uk)
JP (1) JP2002507965A (uk)
KR (2) KR100545946B1 (uk)
CN (1) CN1195762C (uk)
AR (1) AR012250A1 (uk)
AT (1) ATE297935T1 (uk)
AU (1) AU737964B2 (uk)
BR (1) BR9810197B1 (uk)
CA (1) CA2294809C (uk)
CZ (1) CZ299237B6 (uk)
DE (1) DE69830584T2 (uk)
DK (1) DK0991654T3 (uk)
ES (1) ES2244068T3 (uk)
FR (1) FR2764889B1 (uk)
HK (1) HK1030218A1 (uk)
HU (1) HUP0002425A3 (uk)
IL (1) IL133223A (uk)
MY (1) MY123193A (uk)
NO (1) NO315321B1 (uk)
NZ (1) NZ501656A (uk)
PL (1) PL191987B1 (uk)
PT (1) PT991654E (uk)
RU (1) RU2202543C2 (uk)
SK (1) SK286911B6 (uk)
TR (1) TR199903175T2 (uk)
TW (1) TW422842B (uk)
UA (1) UA70921C2 (uk)
WO (1) WO1998058934A1 (uk)
ZA (1) ZA985392B (uk)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
AR019190A1 (es) * 1998-07-08 2001-12-26 Sod Conseils Rech Applic Derivados de 2-aminopiridinas, productos intermedios para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y su uso para preparar medicamentos
EP1103552A4 (en) * 1998-08-07 2003-01-15 Takeda Chemical Industries Ltd BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
FR2783519B1 (fr) * 1998-09-23 2003-01-24 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
FR2798127A1 (fr) 1999-09-03 2001-03-09 Expansia Sa Nouveau procede de preparation d'amidines derivees de l'acide 6-hydroxy-2,5,7,8-tetramethylchrommane-2-carboxy- lique
TWI283577B (en) 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
FR2812546B1 (fr) * 2000-08-01 2008-11-21 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
RU2380362C2 (ru) * 1999-10-11 2010-01-27 Сосьете Де Консей Де Решерш З Производные пятичленных гетероциклов, способ их получения и их применение в качестве лекарственных средств
FR2799461B1 (fr) * 1999-10-11 2002-01-04 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
FR2801053B1 (fr) * 1999-11-16 2004-06-25 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments
SE9904676D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
SE9904677D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
WO2002020511A1 (en) * 2000-09-05 2002-03-14 Astrazeneca Ab Amidine derivatives which are inhibitors of nitric oxide synthase
TWI248438B (en) * 2001-04-10 2006-02-01 Sod Conseils Rech Applic Derivatives of heterocycles with 5 members, their preparation and their use as medicaments
CA2450589C (en) * 2001-06-08 2011-12-20 Cytokine Pharmasciences, Inc. Isoxazoline compounds having mif antagonist activity
HU228783B1 (en) * 2001-07-26 2013-05-28 Greenearth Cleaning Dry cleaning apparatus and method capable of utilizing a siloxane solvent
US7141561B2 (en) 2002-07-25 2006-11-28 Sanofi-Aventis Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments
FR2842808B1 (fr) * 2002-07-25 2004-09-10 Sod Conseils Rech Applic Nouveaux derives d'arylimidazoles, leur preparation et leurs applications therapeutiques
DE10233817A1 (de) * 2002-07-25 2004-02-12 Aventis Pharma Deutschland Gmbh Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
BRPI0507818A (pt) * 2004-03-26 2007-07-10 Cytokine Pharmasciences Inc composto e métodos de inibição
WO2006022442A1 (ja) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. ジヒドロオロテートデヒドロゲナーゼ阻害活性を有する新規複素環アミド誘導体
ZA200707427B (en) * 2005-03-11 2008-11-26 Florey Howard Inst Flavonoid compounds and uses thereof
WO2011029104A1 (en) 2009-09-04 2011-03-10 Vanderbilt University Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
WO2011058766A1 (en) * 2009-11-16 2011-05-19 Raqualia Pharma Inc. Aryl carboxamide derivatives as ttx-s blockers
RS55813B2 (sr) * 2012-07-12 2019-12-31 Khondrion Ip B V Hromanil derivati za tretiranje mitohondrijalne bolesti

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
BR9407515A (pt) * 1993-08-12 1997-01-07 Astra Ab Composto formulação farmaceutica uso do composto processos para o tratamento de desordens neurodegenerativas ou de enxaqueca ou para a prevenção e a reversão da tolerância aos opiatos e diazepinas ou para o tratamento do vicio das drogas e para a preparação do composto
JPH10500138A (ja) * 1994-05-07 1998-01-06 アストラ・アクチエボラーグ 酸化窒素合成酵素阻害剤としての２環アミジン誘導体

Also Published As

Publication number Publication date
FR2764889B1 (fr) 2000-09-01
HUP0002425A3 (en) 2001-12-28
MY123193A (en) 2006-05-31
ZA985392B (en) 1999-01-20
KR100545946B1 (ko) 2006-01-26
TR199903175T2 (xx) 2000-04-21
PL337499A1 (en) 2000-08-28
NO315321B1 (no) 2003-08-18
BR9810197A (pt) 2000-08-08
PL191987B1 (pl) 2006-07-31
DK0991654T3 (da) 2005-10-17
CZ299237B6 (cs) 2008-05-28
NO996208D0 (no) 1999-12-15
CA2294809C (fr) 2010-02-02
ES2244068T3 (es) 2005-12-01
EP0991654A1 (fr) 2000-04-12
PT991654E (pt) 2005-10-31
FR2764889A1 (fr) 1998-12-24
CA2294809A1 (fr) 1998-12-30
IL133223A0 (en) 2001-03-19
CZ459799A3 (cs) 2000-07-12
AU737964B2 (en) 2001-09-06
ATE297935T1 (de) 2005-07-15
HK1030218A1 (en) 2001-04-27
HUP0002425A1 (hu) 2001-11-28
TW422842B (en) 2001-02-21
AR012250A1 (es) 2000-09-27
DE69830584T2 (de) 2006-03-16
JP2002507965A (ja) 2002-03-12
SK286911B6 (sk) 2009-07-06
SK179699A3 (en) 2000-05-16
BR9810197B1 (pt) 2010-02-09
EP0991654B1 (fr) 2005-06-15
NO996208L (no) 2000-02-15
RU2202543C2 (ru) 2003-04-20
KR20010013983A (ko) 2001-02-26
DE69830584D1 (de) 2005-07-21
WO1998058934A1 (fr) 1998-12-30
KR20050098970A (ko) 2005-10-12
AU8218998A (en) 1999-01-04
NZ501656A (en) 2001-12-21
CN1264385A (zh) 2000-08-23
KR100618478B1 (ko) 2006-09-01
IL133223A (en) 2004-09-27
CN1195762C (zh) 2005-04-06

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