SE9904676D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE9904676D0
SE9904676D0 SE9904676A SE9904676A SE9904676D0 SE 9904676 D0 SE9904676 D0 SE 9904676D0 SE 9904676 A SE9904676 A SE 9904676A SE 9904676 A SE9904676 A SE 9904676A SE 9904676 D0 SE9904676 D0 SE 9904676D0
Authority
SE
Sweden
Prior art keywords
novel compounds
compounds
racemates
tautomers
inhibitors
Prior art date
Application number
SE9904676A
Other languages
English (en)
Inventor
Kenneth Mattes
Robert J Murray
Hans F Schmitthenner
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9904676A priority Critical patent/SE9904676D0/sv
Publication of SE9904676D0 publication Critical patent/SE9904676D0/sv
Priority to US09/763,835 priority patent/US20020137736A1/en
Priority to PCT/SE2000/002539 priority patent/WO2001046170A1/en
Priority to AU24176/01A priority patent/AU2417601A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
SE9904676A 1999-12-20 1999-12-20 Novel compounds SE9904676D0 (sv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9904676A SE9904676D0 (sv) 1999-12-20 1999-12-20 Novel compounds
US09/763,835 US20020137736A1 (en) 1999-12-20 2000-12-14 Novel compounds
PCT/SE2000/002539 WO2001046170A1 (en) 1999-12-20 2000-12-14 Amidine derivatives which are inhibitors of nitric oxide synthase
AU24176/01A AU2417601A (en) 1999-12-20 2000-12-14 Amidine derivatives which are inhibitors of nitric oxide synthase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904676A SE9904676D0 (sv) 1999-12-20 1999-12-20 Novel compounds

Publications (1)

Publication Number Publication Date
SE9904676D0 true SE9904676D0 (sv) 1999-12-20

Family

ID=20418212

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9904676A SE9904676D0 (sv) 1999-12-20 1999-12-20 Novel compounds

Country Status (4)

Country Link
US (1) US20020137736A1 (sv)
AU (1) AU2417601A (sv)
SE (1) SE9904676D0 (sv)
WO (1) WO2001046170A1 (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001282829A1 (en) * 2000-09-05 2002-03-22 Astrazeneca Ab Amidine derivatives which are inhibitors of nitric oxide synthase
DE10162114A1 (de) * 2001-12-12 2003-06-26 Schering Ag Neue Amidin-Derivate und deren Verwendung in Arzneimitteln
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) * 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
BR112014032479B1 (pt) * 2012-06-29 2020-03-10 Bayer Cropscience Ag Método de preparação de derivados de 2,2- difluoroetilamina por alquilação da 2,2-difluoroetilamina
CN108794370A (zh) * 2018-07-31 2018-11-13 上海弈柯莱生物医药科技有限公司 一种拉罗替尼中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2132393T3 (es) * 1993-03-23 1999-08-16 Astra Ab Derivados de guanidina utiles en terapeutica.
RU2130017C1 (ru) * 1993-08-12 1999-05-10 Астра Актиенболаг Производные амидина, способ их получения и лекарственное средство на их основе, обладающее свойством ингибировать активность синтетазы оксида азота (у)
FR2761066B1 (fr) * 1997-03-24 2000-11-24 Sod Conseils Rech Applic Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
FR2764889B1 (fr) * 1997-06-20 2000-09-01 Sod Conseils Rech Applic Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
JPH10265450A (ja) * 1997-03-25 1998-10-06 Mitsui Chem Inc 一酸化窒素合成酵素阻害作用を有する新規なアミジン誘導体

Also Published As

Publication number Publication date
AU2417601A (en) 2001-07-03
US20020137736A1 (en) 2002-09-26
WO2001046170A1 (en) 2001-06-28

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