SE0102641D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0102641D0
SE0102641D0 SE0102641A SE0102641A SE0102641D0 SE 0102641 D0 SE0102641 D0 SE 0102641D0 SE 0102641 A SE0102641 A SE 0102641A SE 0102641 A SE0102641 A SE 0102641A SE 0102641 D0 SE0102641 D0 SE 0102641D0
Authority
SE
Sweden
Prior art keywords
novel compounds
compounds
racemates
prophylaxis
enantiomers
Prior art date
Application number
SE0102641A
Other languages
English (en)
Inventor
David Cheshire
Stephen Connolly
Antonio Mete
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0102641A priority Critical patent/SE0102641D0/sv
Publication of SE0102641D0 publication Critical patent/SE0102641D0/sv
Priority to US10/483,140 priority patent/US20040176422A1/en
Priority to PCT/SE2002/001413 priority patent/WO2003011830A1/en
Priority to JP2003517022A priority patent/JP2005501834A/ja
Priority to AT02749497T priority patent/ATE324368T1/de
Priority to DE60210981T priority patent/DE60210981T2/de
Priority to EP02749497A priority patent/EP1414802B1/en
Priority to ES02749497T priority patent/ES2261696T3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
SE0102641A 2001-07-31 2001-07-31 Novel compounds SE0102641D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE0102641A SE0102641D0 (sv) 2001-07-31 2001-07-31 Novel compounds
US10/483,140 US20040176422A1 (en) 2001-07-31 2002-07-26 Heteroarylheteroalkylamine derivatives and their use as inhibitors of nitric oxide synthase
PCT/SE2002/001413 WO2003011830A1 (en) 2001-07-31 2002-07-26 Heteroarylheteroalkylamine derivatives and their use as inhibitors of nitric oxide synthase
JP2003517022A JP2005501834A (ja) 2001-07-31 2002-07-26 ヘテロアリールヘテロアルキルアミン誘導体、および一酸化窒素合成酵素阻害剤としてのその使用
AT02749497T ATE324368T1 (de) 2001-07-31 2002-07-26 Heteroarylheteroalkylamin derivate und deren verwendung als inhibitoren der stickoxidsynthase
DE60210981T DE60210981T2 (de) 2001-07-31 2002-07-26 Heteroarylheteroalkylamin derivate und deren verwendung als inhibitoren der stickoxidsynthase
EP02749497A EP1414802B1 (en) 2001-07-31 2002-07-26 Heteroarylheteroalkylamine derivatives and their use as inhibitors of nitric oxide synthase
ES02749497T ES2261696T3 (es) 2001-07-31 2002-07-26 Derivados de heteroarilheteroalquilaminas y su uso como inhibidores de la sintasa de oxido nitrico.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0102641A SE0102641D0 (sv) 2001-07-31 2001-07-31 Novel compounds

Publications (1)

Publication Number Publication Date
SE0102641D0 true SE0102641D0 (sv) 2001-07-31

Family

ID=20284966

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0102641A SE0102641D0 (sv) 2001-07-31 2001-07-31 Novel compounds

Country Status (8)

Country Link
US (1) US20040176422A1 (sv)
EP (1) EP1414802B1 (sv)
JP (1) JP2005501834A (sv)
AT (1) ATE324368T1 (sv)
DE (1) DE60210981T2 (sv)
ES (1) ES2261696T3 (sv)
SE (1) SE0102641D0 (sv)
WO (1) WO2003011830A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
SE0102639D0 (sv) * 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
SE0203304D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Coumpounds
JP4988576B2 (ja) * 2004-09-10 2012-08-01 シンジェンタ リミテッド 殺真菌剤としての置換されたイソオキサゾール
DE102006031813B4 (de) * 2006-07-07 2011-04-28 Christian-Albrechts-Universität Zu Kiel Verwendung basischer Acetophenone als Hemmstoffe von NO-Synthasen
WO2008150528A1 (en) * 2007-06-04 2008-12-11 Intra-Cellular Therapies, Inc. Novel methods
CN102775365A (zh) * 2011-05-10 2012-11-14 无锡立诺康医药科技有限公司 5-氨基取代基-异噁唑类化合物或其酸式盐的合成工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US139350A (en) * 1873-05-27 Improvement in cutters for sewing-machines
JPS5144934B1 (sv) * 1969-12-09 1976-12-01
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB2060622B (en) * 1979-09-14 1983-05-25 Wyeth John & Brother Ltd 3-aryl-3-aryloxyalkylamines
US4325953A (en) * 1979-09-14 1982-04-20 John Wyeth And Brother Limited 4-Aryl-4-aryloxypiperidines
US4295126A (en) * 1980-10-02 1981-10-13 Itt Industries, Inc. MOS-Binary-to-decimal code converter
DE3138550A1 (de) * 1981-09-28 1983-04-07 Boehringer Ingelheim KG, 6507 Ingelheim Substituierte 2-phenyl-2-(pyridyloxy)-ethylamine und isostere verbindungen, verfahren zu ihrer herstellung und verwendung
US4902710A (en) * 1988-12-14 1990-02-20 Eli Lilly And Company Serotonin and norepinephrine uptake inhibitors
DK258389D0 (da) * 1989-05-26 1989-05-26 Ferrosan As Aryloxyphenylpropylaminer, deres fremstilling og anvendelse
EP0571685A1 (en) * 1992-05-27 1993-12-01 Novo Nordisk A/S Aryloxyheteroarylpropylamines, their preparation and use
ES2169102T3 (es) * 1994-10-14 2002-07-01 Merck Patent Gmbh (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central.
GB0004149D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds

Also Published As

Publication number Publication date
JP2005501834A (ja) 2005-01-20
US20040176422A1 (en) 2004-09-09
DE60210981T2 (de) 2007-05-10
WO2003011830A1 (en) 2003-02-13
DE60210981D1 (de) 2006-06-01
EP1414802B1 (en) 2006-04-26
ATE324368T1 (de) 2006-05-15
ES2261696T3 (es) 2006-11-16
EP1414802A1 (en) 2004-05-06

Similar Documents

Publication Publication Date Title
MXPA03010142A (es) Nuevos derivados de arilheteroalquilamina.
SE0302487D0 (sv) Novel compounds
SE9803518D0 (sv) Novel compounds
SE0202463D0 (sv) Novel compounds
NO20025601L (no) Arylmetylaminderivater for anvendelse som tryptaseinhibitorer
CO5271691A1 (es) Nuevos compuestos
ATE331711T1 (de) Entzündungshemmende 3-arylthio-3- thiazolylalkylamine
SE0302324D0 (sv) Novel compounds
GB0004153D0 (en) Novel use
SE0302323D0 (sv) Novel compounds
SE9701304D0 (sv) Compounds
SE9803773D0 (sv) Compounds
SE0302756D0 (sv) Novel Compounds
AU2001290480A1 (en) Cyclized benzamide neurokinin antagonists for use in therapy
SE0102641D0 (sv) Novel compounds
ATE265423T1 (de) Neue phenylheteroalkylamin-derivate
SE0102640D0 (sv) Novel compounds
SE0102639D0 (sv) Novel compounds
SE0103325D0 (sv) Novel compounds
SE0202280D0 (sv) Novel compounds
SE0300907D0 (sv) Novel compounds
SE9904676D0 (sv) Novel compounds
SE9901530D0 (sv) Novel compounds
SE9901901D0 (sv) Compounds
SE0300906D0 (sv) Novel compounds