ZA924719B - Pharmaceutical composition - Google Patents

Pharmaceutical composition

Info

Publication number
ZA924719B
ZA924719B ZA924719A ZA924719A ZA924719B ZA 924719 B ZA924719 B ZA 924719B ZA 924719 A ZA924719 A ZA 924719A ZA 924719 A ZA924719 A ZA 924719A ZA 924719 B ZA924719 B ZA 924719B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
ZA924719A
Other languages
English (en)
Inventor
Armin Meinzer
Birgit Hauer
Ulrich Posanski
Jacky Vonderscher
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10697415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA924719(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA924719B publication Critical patent/ZA924719B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/06—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with glycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
ZA924719A 1991-06-27 1992-06-25 Pharmaceutical composition ZA924719B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919113872A GB9113872D0 (en) 1991-06-27 1991-06-27 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
ZA924719B true ZA924719B (en) 1993-12-27

Family

ID=10697415

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA924719A ZA924719B (en) 1991-06-27 1992-06-25 Pharmaceutical composition

Country Status (38)

Country Link
EP (2) EP0539319B1 (xx)
JP (2) JP2653958B2 (xx)
KR (3) KR0131064B1 (xx)
CN (1) CN1077798C (xx)
AT (1) AT403436B (xx)
AU (1) AU659460B2 (xx)
CA (2) CA2175842C (xx)
CH (2) CH684163A5 (xx)
CY (1) CY1906A (xx)
CZ (1) CZ281790B6 (xx)
DE (3) DE4219526C2 (xx)
DK (2) DK0953630T3 (xx)
EE (1) EE03108B1 (xx)
ES (2) ES2227921T3 (xx)
FI (2) FI109454B (xx)
FR (2) FR2678169B1 (xx)
GB (2) GB9113872D0 (xx)
GR (1) GR3032366T3 (xx)
HK (2) HK57196A (xx)
HU (1) HU216792B (xx)
IE (1) IE73662B1 (xx)
IL (3) IL102310A (xx)
IT (1) IT1254401B (xx)
LU (1) LU88138A1 (xx)
MX (1) MX9203236A (xx)
MY (1) MY109512A (xx)
NO (2) NO303964B1 (xx)
NZ (1) NZ243309A (xx)
PH (1) PH30337A (xx)
PT (2) PT539319E (xx)
RO (2) RO111021B1 (xx)
RU (1) RU2143919C1 (xx)
SA (1) SA92130213B1 (xx)
SK (1) SK278759B6 (xx)
TW (1) TW267943B (xx)
UA (1) UA35559C2 (xx)
UY (1) UY23864A1 (xx)
ZA (1) ZA924719B (xx)

Families Citing this family (70)

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DK0589843T3 (da) * 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
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US5891846A (en) * 1994-02-17 1999-04-06 Shiseido Company, Ltd. Cyclosporin-containing emulsion composition
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GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
DE69510404T2 (de) * 1994-03-31 2000-01-20 Loders Croklaan Bv Öle mit niedrigem Gehalt an gesättigter Fettsäure
PE52896A1 (es) 1994-10-26 1996-12-12 Novartis Ag Composicion farmaceutica
GB2308545B (en) * 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
CN1121238C (zh) 1994-11-03 2003-09-17 诺瓦蒂斯有限公司 口服施用的具有简单组成和高生物利用度的环孢菌素新制剂形式及其制造方法
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
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EP0827402A2 (en) * 1995-05-17 1998-03-11 Cedars-Sinai Medical Center Compositions containing fatty acids for improving digestion and absorption in the small intestine
US6008228A (en) * 1995-06-06 1999-12-28 Hoffman-La Roche Inc. Pharmaceutical compositions containing proteinase inhibitors
US6696413B2 (en) * 1995-06-16 2004-02-24 Hexal Ag Pharmaceutical preparation with cyclosporin A
SE504582C2 (sv) * 1995-07-06 1997-03-10 Gs Dev Ab Cyklosporinkomposition baserad på en L2-fas
DE19544507B4 (de) * 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
CN1104258C (zh) * 1996-05-29 2003-04-02 周德和 用于环孢霉素a的赋形剂
RU2181055C2 (ru) * 1996-06-19 2002-04-10 Новартис Аг Препараты, содержащие циклоспорин, в виде капсул с мягким покрытием
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
KR980008239A (ko) * 1996-07-26 1998-04-30 김충환 사이클로스포린-함유 약학적 조성물
FR2752732B1 (fr) * 1996-08-28 1998-11-20 Pf Medicament Forme galenique a liberation prolongee de milnacipran
ZA9711732B (en) 1996-12-31 1998-12-28 Quadrant Holdings Cambridge Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery
HU228855B1 (en) * 1997-03-12 2013-06-28 Abbott Lab Hydrophilic binary systems for the administration of cyclosporine
NZ314702A (en) * 1997-04-29 1998-07-28 Bernard Charles Sherman Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent
CA2285983A1 (en) 1997-04-29 1998-11-05 Bernard Charles Sherman Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride
GB2326337A (en) 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
CZ296957B6 (cs) 1997-07-29 2006-08-16 Pharmacia & Upjohn Company Farmaceutická kompozice pro kyselé lipofilní slouceniny ve forme samoemulgující formulace
BR9811058A (pt) * 1997-07-29 2000-09-05 Upjohn Co Formulação auto-emulsificante para compostos lipofìlicos
BR9810866B1 (pt) * 1997-07-29 2010-07-13 composição farmacêutica em uma forma de formulação auto-emulsificante para compostos lipofìlicos.
AU748334B2 (en) 1997-10-16 2002-05-30 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with NF-AT3 function
AU1508899A (en) * 1997-12-02 1999-06-16 Chong Kun Dang Corporation Pharmaceutical composition comprising cyclosporin solid-state microemulsion
KR100587551B1 (ko) 1997-12-10 2006-06-08 싸이클로스포린 테라퓨틱스 리미티드 오메가-3 지방산 오일을 함유하는 약학 조성물
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
DE69822814T2 (de) * 1998-08-18 2005-01-27 Panacea Biotec Ltd. Zusammensetzung enthaltend Cyclosporin in einem hydrophilen Träger
GB9903547D0 (en) 1999-02-16 1999-04-07 Novartis Ag Organic compounds
CN1167462C (zh) * 1999-03-09 2004-09-22 杭州华东医药集团生物工程研究所有限公司 一种含环孢素的药物组合物
US6956048B2 (en) 1999-03-31 2005-10-18 Pharmacia & Upjohn Company Pharmaceutical emulsions for retroviral protease inhibitors
WO2001032143A1 (en) * 1999-11-02 2001-05-10 Cipla Ltd. A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and a process for preparation thereof
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
DE60123849T2 (de) 2000-08-08 2007-05-24 Kao Corp. Öl-/fett-zusammensetzung
US7115565B2 (en) 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7141648B2 (en) 2001-10-19 2006-11-28 Isotechnika Inc. Synthesis of cyclosporin analogs
KR100441167B1 (ko) * 2001-12-27 2004-07-21 씨제이 주식회사 마이크로에멀젼 예비 농축액 조성물
KR100525234B1 (ko) * 2003-02-19 2005-10-28 한국유나이티드제약 주식회사 사이클로스포린 함유 연질캅셀제 및 그 제조방법
GT200500310A (es) 2004-11-19 2006-06-19 Compuestos organicos
GB0504950D0 (en) 2005-03-10 2005-04-20 Novartis Ag Organic compositions
JP4889262B2 (ja) * 2005-08-19 2012-03-07 理研ビタミン株式会社 脂溶性薬剤組成物
MD3347G2 (ro) * 2006-12-26 2008-01-31 Институт Сельскохозяйственной Техники "Mecagro" Procedeu de obţinere a esterilor metilici din ulei de rapiţă
ITPD20070049A1 (it) * 2007-02-14 2008-08-15 Sila S R L Prodotto a base di acido linoleico coniugato e processo per la sua fabbricazione
ES2393814T3 (es) 2007-04-04 2012-12-28 Sigmoid Pharma Limited Una composición farmacéutica oral
CN101199836B (zh) * 2007-11-07 2011-03-30 安徽省药物研究所 一种阶段释放型环孢素a固体微乳制剂及其微乳固化方法
US9278070B2 (en) 2009-05-18 2016-03-08 Sigmoid Pharma Limited Composition comprising oil drops
EP2464341B1 (en) 2009-08-12 2022-07-06 Sublimity Therapeutics Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
FR2971941B1 (fr) 2011-02-24 2013-08-02 Physica Pharma Compositions pharmaceutiques administrables par voie cutanee et destinees au traitement local de la dermatite atopique canine
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WO2020050182A1 (ja) * 2018-09-06 2020-03-12 株式会社カマタ カプセル充填用液状組成物及びカプセル剤

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BE895724A (fr) * 1982-02-01 1983-07-28 Sandoz Sa Nouvelle utilisation therapeutique de la dihydrocyclosporine d
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Also Published As

Publication number Publication date
NO325267B1 (no) 2008-03-17
ES2227921T3 (es) 2005-04-01
EP0539319A3 (en) 1993-06-09
FI116199B (fi) 2005-10-14
KR100231384B1 (en) 1999-11-15
GB9113872D0 (en) 1991-08-14
NO922506D0 (no) 1992-06-25
CZ197792A3 (en) 1993-01-13
HU9201975D0 (en) 1992-09-28
ES2142818T3 (es) 2000-05-01
FI961513A0 (fi) 1996-04-03
EP0539319A2 (en) 1993-04-28
NO303964B1 (no) 1998-10-05
JPH05186365A (ja) 1993-07-27
JP2653958B2 (ja) 1997-09-17
EE03108B1 (et) 1998-08-17
EP0539319B1 (en) 1999-12-08
NZ243309A (en) 1995-02-24
GR3032366T3 (en) 2000-04-27
DE4244930C2 (de) 1999-11-11
IT1254401B (it) 1995-09-14
FI922958A0 (fi) 1992-06-25
RU2143919C1 (ru) 2000-01-10
AU1852792A (en) 1993-03-11
FR2685706B1 (xx) 1994-12-23
MX9203236A (es) 1992-12-01
SA92130213B1 (ar) 2004-07-24
HUT62201A (en) 1993-04-28
FR2685706A1 (fr) 1993-07-02
HK57196A (en) 1996-04-12
IL102310A (en) 1997-03-18
CZ281790B6 (cs) 1997-01-15
KR0131064B1 (ko) 1998-04-17
IE73662B1 (en) 1997-06-18
ITRM920476A1 (it) 1993-12-23
KR100231385B1 (en) 1999-11-15
CA2175842A1 (en) 1992-12-28
CA2072509A1 (en) 1992-12-28
FI961513A (fi) 1996-04-03
GB2257359B (en) 1996-01-10
PT953630E (pt) 2004-11-30
DE4219526C2 (de) 1999-04-22
RO111110B1 (ro) 1996-06-28
DE4219526A1 (de) 1993-03-18
GB2257359A (en) 1993-01-13
CH684163A5 (de) 1994-07-29
JP3420897B2 (ja) 2003-06-30
HK157696A (en) 1996-08-30
CY1906A (en) 1992-06-24
PH30337A (en) 1997-04-02
FI109454B (fi) 2002-08-15
IL118546A0 (en) 1996-10-16
KR930000113A (ko) 1993-01-15
MY109512A (en) 1997-02-28
UA35559C2 (uk) 2001-04-16
AT403436B (de) 1998-02-25
RO111021B1 (ro) 1996-06-28
DE4244986B4 (de) 2008-07-24
LU88138A1 (fr) 1994-03-01
TW267943B (xx) 1996-01-11
ATA129892A (de) 1997-07-15
FR2678169A1 (fr) 1992-12-31
NO964382L (no) 1992-12-28
PT539319E (pt) 2000-05-31
IE922082A1 (en) 1992-12-30
ITRM920476A0 (it) 1992-06-23
SK278759B6 (sk) 1998-02-04
CN1079907A (zh) 1993-12-29
CN1077798C (zh) 2002-01-16
IL118546A (en) 1998-09-24
CA2175842C (en) 2002-05-07
FR2678169B1 (fr) 1994-08-26
FI922958A (fi) 1992-12-28
CA2072509C (en) 1996-07-30
GB9213393D0 (en) 1992-08-05
JPH09118894A (ja) 1997-05-06
NO922506L (no) 1992-12-28
CH685764A5 (de) 1995-09-29
NO964382D0 (no) 1996-10-15
AU659460B2 (en) 1995-05-18
IL102310A0 (en) 1993-01-14
DK0953630T3 (da) 2004-11-01
SK197792A3 (en) 1994-03-09
HU216792B (hu) 1999-08-30
UY23864A1 (es) 1995-05-29
EP0953630A1 (en) 1999-11-03
DK0539319T3 (da) 2000-05-22
EP0953630B1 (en) 2004-09-08

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