ZA87471B - Indolizine derivatives,process for preparing them and the compositions containing them - Google Patents

Indolizine derivatives,process for preparing them and the compositions containing them

Info

Publication number
ZA87471B
ZA87471B ZA87471A ZA87471A ZA87471B ZA 87471 B ZA87471 B ZA 87471B ZA 87471 A ZA87471 A ZA 87471A ZA 87471 A ZA87471 A ZA 87471A ZA 87471 B ZA87471 B ZA 87471B
Authority
ZA
South Africa
Prior art keywords
preparing
compositions containing
indolizine derivatives
indolizine
derivatives
Prior art date
Application number
ZA87471A
Other languages
English (en)
Inventor
Jean Gubin
Pierre Chatelain
Marcel Descamps
Dino Nisato
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA87471B publication Critical patent/ZA87471B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA87471A 1986-02-14 1987-01-22 Indolizine derivatives,process for preparing them and the compositions containing them ZA87471B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8602045A FR2594438B1 (fr) 1986-02-14 1986-02-14 Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant

Publications (1)

Publication Number Publication Date
ZA87471B true ZA87471B (en) 1988-09-28

Family

ID=9332147

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA87471A ZA87471B (en) 1986-02-14 1987-01-22 Indolizine derivatives,process for preparing them and the compositions containing them

Country Status (33)

Country Link
US (5) US4957925A (ko)
EP (1) EP0235111B1 (ko)
JP (1) JP2547004B2 (ko)
KR (1) KR870007931A (ko)
AR (1) AR245127A1 (ko)
AT (1) ATE62485T1 (ko)
AU (1) AU587525B2 (ko)
BE (1) BE1006666A4 (ko)
CA (1) CA1310965C (ko)
CZ (1) CZ281209B6 (ko)
DD (1) DD264436A5 (ko)
DE (1) DE3769174D1 (ko)
DK (1) DK170403B1 (ko)
ES (1) ES2040276T3 (ko)
FI (1) FI84353C (ko)
FR (1) FR2594438B1 (ko)
GR (1) GR3001883T3 (ko)
HU (1) HU196401B (ko)
IE (1) IE59656B1 (ko)
IL (1) IL81358A (ko)
MA (1) MA20878A1 (ko)
MY (1) MY101541A (ko)
NO (1) NO165344C (ko)
NZ (1) NZ219274A (ko)
OA (1) OA08481A (ko)
PH (1) PH24830A (ko)
PL (2) PL153650B1 (ko)
PT (1) PT84277B (ko)
SK (1) SK279557B6 (ko)
SU (2) SU1486064A3 (ko)
TN (1) TNSN87021A1 (ko)
YU (2) YU21287A (ko)
ZA (1) ZA87471B (ko)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
US5182291A (en) * 1986-02-14 1993-01-26 Sanofi Pyrozala-pyridyl aminoabkoxyphenol compounds
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2633622B1 (fr) * 1988-07-04 1991-05-17 Sanofi Sa Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
CA2008985A1 (en) * 1989-02-06 1990-08-06 Jean Gubin Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (ko) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5118707A (en) * 1990-10-31 1992-06-02 The Procter & Gamble Company Compositions for regulating skin wrinkles comprising a benzofuran derivative
US5435991A (en) * 1991-08-09 1995-07-25 Nycomed Innovation Ab Use of persistent heterocyclic free-radicals in magnetic resonance imaging
FR2692574B1 (fr) * 1992-06-23 1995-06-23 Sanofi Elf Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles.
FR2692578B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Derives d'indolizines, procede de preparation et utilisation pour la preparation de composes aminoalkoxybenzenesulfonyl-indolizines a activite pharmaceutique.
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
FR2725133B1 (fr) * 1994-09-30 1996-12-20 Sanofi Sa Composition pharmaceutique de fantofarone pour administration orale
US6514971B1 (en) 1996-03-15 2003-02-04 Zeneca Limited Cinnoline derivatives and use as medicine
US6482854B1 (en) 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
US6699866B2 (en) * 2001-04-17 2004-03-02 Sepracor Inc. Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof
PL214231B1 (pl) * 2001-04-27 2013-07-31 Eisai R & D Man Co Pochodne pirazolo [1,5-a] pirydyny, kompozycje je zawierajace oraz zastosowanie
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
AU2003274053A1 (en) * 2002-10-22 2004-05-13 Glaxo Group Limited Aryloxyalkylamine derivates as h3 receptor ligands
CN100528883C (zh) * 2003-01-31 2009-08-19 日本曹达株式会社 形成光变换性有机薄膜的新型化合物和有机薄膜形成体
AU2004268614C1 (en) 2003-08-27 2010-10-28 Ophthotech Corporation Combination therapy for the treatment of ocular neovascular disorders
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101582A1 (en) * 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) * 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20050250737A1 (en) * 2003-11-12 2005-11-10 Allergan, Inc. Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
JP2007518804A (ja) 2004-01-20 2007-07-12 アラーガン、インコーポレイテッド トリアムシノロンアセトニドおよびヒアルロン酸を好ましく含有する眼局所治療用組成物
US20050244458A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
US7993634B2 (en) * 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US8119154B2 (en) * 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US8147865B2 (en) * 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
WO2005107708A1 (en) 2004-04-30 2005-11-17 Allergan, Inc. Biodegradable intravitreal tyrosine kinase inhibitors implants
US20050244472A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
US20050244471A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Estradiol derivative and estratopone containing sustained release intraocular implants and related methods
US20070059336A1 (en) * 2004-04-30 2007-03-15 Allergan, Inc. Anti-angiogenic sustained release intraocular implants and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US20050244466A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Photodynamic therapy in conjunction with intraocular implants
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US20050244462A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US20050244478A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Anti-excititoxic sustained release intraocular implants and related methods
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8591885B2 (en) * 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US20050244461A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Controlled release drug delivery systems and methods for treatment of an eye
JP2008505978A (ja) * 2004-07-12 2008-02-28 アラーガン、インコーポレイテッド 眼病用組成物および眼病治療法
WO2006073938A2 (en) * 2004-12-30 2006-07-13 East Carolina University Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
US20090017112A1 (en) * 2006-03-01 2009-01-15 Roskamp Research Llc Compounds for Inhibiting Beta-Amyloid Production
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
EP2120557A4 (en) * 2006-12-08 2010-02-10 Roskamp Res Llc POLYHYDROQUINOLINE COMPOUNDS AND DIHYDROPYRIDINE COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION
US7911053B2 (en) * 2007-04-19 2011-03-22 Marvell World Trade Ltd. Semiconductor packaging with internal wiring bus
SI2266990T1 (sl) * 2008-04-15 2013-01-31 Eisai R&D Management Co. Ltd. Spojina 3-fenilpirazolo(5,1-b)tiazola
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
JPWO2011043387A1 (ja) * 2009-10-08 2013-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
CN102724951A (zh) 2009-11-09 2012-10-10 阿勒根公司 用于刺激毛发生长的组合物和方法
EP2956096A1 (en) 2013-02-15 2015-12-23 Allergan, Inc. Sustained drug delivery implant
CN108084186B (zh) * 2016-11-16 2021-06-25 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
EP4426434A1 (en) 2021-11-02 2024-09-11 Flare Therapeutics, Inc. Pparg inverse agonists and uses thereof

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1720033A1 (de) * 1966-03-02 1971-05-19 Yoshitomi Pharmaceutical Neue Indolderivate und Verfahren zu ihrer Herstellung
US3485835A (en) * 1968-04-10 1969-12-23 Haessle Ab 2-benzoyl-3-tertiaryamino alkoxy benzofuran derivatives
IL32186A (en) * 1968-05-24 1974-10-22 Fisons Ltd 5-benzofuranyl compounds,their preparation,and physiologically active compositions containing them
US3860609A (en) * 1969-05-27 1975-01-14 Novo Terapeutisk Labor As 3-aminoalkyloxyindoles
US3859305A (en) * 1970-03-10 1975-01-07 Degussa Indole aminoketones
SE379196B (ko) * 1971-06-24 1975-09-29 Sandoz Ag
US3947470A (en) * 1974-06-20 1976-03-30 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4013012A (en) * 1974-11-18 1977-03-22 Altus Corporation Electronic safe arming and fuzing system
FI61030C (fi) * 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
US4117128A (en) * 1976-08-03 1978-09-26 Smithkline Corporation Sulfonyl benzofurans and benzothiophenes having coronary vasodilator activity
FR2376145A1 (fr) * 1977-01-03 1978-07-28 Thea Therapeutiques Applic Sa Nouveaux derives de chromones a activite medicamenteuse et leur preparation
GB1560006A (en) * 1977-08-18 1980-01-30 Laroche Navarron Sa Benzoyl furan derivatives process for their preparation and therapeutic applications thereof
US4128552A (en) * 1977-09-26 1978-12-05 Warner-Lambert Company 1-[4,4-Bis(4-fluorophenyl)butyl]-4-phenylthio-1,2,3,6-tetrahydropyridines and related sulfoxides and sulfones
JPS59204191A (ja) * 1983-03-26 1984-11-19 Kyorin Pharmaceut Co Ltd ピラゾロピリジン誘導体、その製法及びそれを含有する治療剤
US4654360A (en) * 1984-06-01 1987-03-31 Syntex (U.S.A.) Inc. 1,2,3-trisubstituted indoles for treatment of inflammation
DE3426419A1 (de) * 1984-07-18 1986-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
US4675405A (en) * 1984-09-21 1987-06-23 American Home Products Corporation Quinoline compounds as antiallergic and antithrombotic agents
FR2584723B1 (fr) * 1985-07-09 1988-02-12 Adir Nouveaux derives du dihydro-2,3 benzofuranne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US4873259A (en) * 1987-06-10 1989-10-10 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them

Also Published As

Publication number Publication date
NO165344B (no) 1990-10-22
CA1310965C (en) 1992-12-01
ATE62485T1 (de) 1991-04-15
EP0235111B1 (fr) 1991-04-10
DK74087A (da) 1987-08-15
IL81358A0 (en) 1987-08-31
AU587525B2 (en) 1989-08-17
MY101541A (en) 1991-12-17
IE870345L (en) 1987-08-14
JPS62192380A (ja) 1987-08-22
AU6884687A (en) 1987-08-20
BE1006666A4 (fr) 1994-11-16
HUT43604A (en) 1987-11-30
DK170403B1 (da) 1995-08-21
YU21287A (en) 1988-08-31
IL81358A (en) 1991-03-10
US5039700A (en) 1991-08-13
MA20878A1 (fr) 1987-10-01
NO870579L (no) 1987-08-17
JP2547004B2 (ja) 1996-10-23
NO870579D0 (no) 1987-02-13
US4994474A (en) 1991-02-19
ES2040276T3 (es) 1993-10-16
OA08481A (fr) 1988-07-29
HU196401B (en) 1988-11-28
TNSN87021A1 (fr) 1990-01-01
US5147878A (en) 1992-09-15
IE59656B1 (en) 1994-03-09
FR2594438A1 (fr) 1987-08-21
NZ219274A (en) 1989-04-26
FI870629A (fi) 1987-08-15
DK74087D0 (da) 1987-02-13
GR3001883T3 (en) 1992-11-23
PT84277A (en) 1987-03-01
EP0235111A1 (fr) 1987-09-02
DE3769174D1 (de) 1991-05-16
DD264436A5 (de) 1989-02-01
SU1528321A3 (ru) 1989-12-07
US5017579A (en) 1991-05-21
PL153650B1 (en) 1991-05-31
US4957925A (en) 1990-09-18
AR245127A1 (es) 1993-12-30
FI84353B (fi) 1991-08-15
NO165344C (no) 1991-01-30
SK97787A3 (en) 1998-12-02
CZ97787A3 (en) 1996-07-17
KR870007931A (ko) 1987-09-23
PH24830A (en) 1990-10-30
PL152609B1 (en) 1991-01-31
PL264078A1 (en) 1988-07-21
CZ281209B6 (cs) 1996-07-17
FI870629A0 (fi) 1987-02-13
YU46588A (en) 1989-08-31
SK279557B6 (sk) 1998-12-02
FI84353C (fi) 1991-11-25
SU1486064A3 (ru) 1989-06-07
FR2594438B1 (fr) 1990-01-26
PT84277B (pt) 1989-09-14

Similar Documents

Publication Publication Date Title
ZA87471B (en) Indolizine derivatives,process for preparing them and the compositions containing them
EG19242A (en) Process for preparing oral compositions.
IL83467A0 (en) Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same
IL84522A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL83760A (en) 3-pyrazoliomethyl-3- cephem-4-carboxylate derivatives, process for the preparation thereof, and pharmacetuical compositions containing the same
ZA859756B (en) Peptide-aldehydes,process for the preparation thereof and pharmaceutical compositions containing the same
PT85239A (en) Process for the preparation of-aryl-phenyl-ethyl-1h-1,2,4-triazole-1-propanenitriles
PT76596A (en) Process for preparing 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
IL87809A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL84589A0 (en) Pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them
IL87542A (en) Arylenediamino substituted triazine derivatives, processes for the preparation thereof and compositions containing the same
HUT44435A (en) Process for preparing stable nicorandyl compositions
OA08608A (en) Pestical compositions and process for preparation thereof.
NZ226131A (en) Cholecalciferol derivatives; compositions, precursors and processes for preparation
IL86027A (en) 2-acylpyrrolidine derivatives,a process for the preparation thereof,compositions containing them,and their use
ZA818867B (en) Pyrazoloindazole derivatives,process for preparing the same,and pharmaceutical compositions containing the same
IL87563A (en) Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL84955A0 (en) Novel carbamoyloxylabdanes,process for the preparation thereof and pharmaceutical compositions containing them
ZA856431B (en) 1,6-naphthyridine derivatives,process for the preparation and the use thereof
ZA876305B (en) 3-perfluoroalkyl-5-substituted-oxy-isoxazole derivatives,process for preparing the same,and herbicides containing the same
PT84441B (en) Process for preparing benzylpyrimidine derivatives and compositions containing them
ZA871756B (en) Arylazolylmethylbenzocycloalkene derivatives,processes for the preparation thereof,and the use thereof
DE3479656D1 (en) Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same
EP0282895A3 (en) 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
EP0246861A3 (en) Pharmaceutical composition based on crotoxine, process for preparing the active component and the pharmaceutical composition