ZA824537B - Compounds - Google Patents

Compounds

Info

Publication number
ZA824537B
ZA824537B ZA824537A ZA824537A ZA824537B ZA 824537 B ZA824537 B ZA 824537B ZA 824537 A ZA824537 A ZA 824537A ZA 824537 A ZA824537 A ZA 824537A ZA 824537 B ZA824537 B ZA 824537B
Authority
ZA
South Africa
Prior art keywords
pyridyl
sub
oxo
sup
dimethyl
Prior art date
Application number
ZA824537A
Other languages
English (en)
Inventor
George Sidney Sach
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of ZA824537B publication Critical patent/ZA824537B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Treating Waste Gases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA824537A 1981-06-27 1982-06-25 Compounds ZA824537B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8119906 1981-06-27

Publications (1)

Publication Number Publication Date
ZA824537B true ZA824537B (en) 1983-05-25

Family

ID=10522859

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA824537A ZA824537B (en) 1981-06-27 1982-06-25 Compounds
ZA824580A ZA824580B (en) 1981-06-27 1982-06-28 Compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA824580A ZA824580B (en) 1981-06-27 1982-06-28 Compounds

Country Status (27)

Country Link
US (4) US4444772A (de)
EP (2) EP0068833B1 (de)
JP (4) JPS588079A (de)
KR (1) KR880001475B1 (de)
AT (2) ATE22891T1 (de)
AU (2) AU551066B2 (de)
BG (1) BG38163A3 (de)
CS (1) CS241036B2 (de)
DD (1) DD202291A5 (de)
DE (2) DE3273019D1 (de)
DK (2) DK287082A (de)
ES (1) ES513469A0 (de)
FI (1) FI822281L (de)
GR (2) GR74925B (de)
HU (1) HU190396B (de)
IE (1) IE53348B1 (de)
IL (1) IL66125A (de)
JO (1) JO1185B1 (de)
NO (1) NO822120L (de)
NZ (1) NZ201077A (de)
PH (1) PH19680A (de)
PL (3) PL137627B1 (de)
PT (1) PT75074B (de)
SU (1) SU1232145A3 (de)
YU (1) YU138982A (de)
ZA (2) ZA824537B (de)
ZW (1) ZW13082A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (de) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
GR78463B (de) * 1982-03-25 1984-09-27 Smith Kline French Lab
ATE33832T1 (de) * 1982-03-25 1988-05-15 Smith Kline French Lab Verfahren zur herstellung von 3,5disubstituierten 2-pyridylalkylaminen.
PT77287B (en) * 1982-10-01 1986-02-04 Smith Kline French Lab Compound
GB8319874D0 (en) * 1983-07-23 1983-08-24 Smith Kline French Lab Compounds
CA1286297C (en) * 1985-06-13 1991-07-16 George S. Sach Pyridine derivatives
GB8601816D0 (en) * 1986-01-25 1986-02-26 Smith Kline French Lab Pyridine derivatives
GB8610867D0 (en) * 1986-05-02 1986-06-11 Smith Kline French Lab 3-hydroxypyridines
JP2679977B2 (ja) * 1986-09-19 1997-11-19 株式会社日立製作所 半導体集積回路
WO1989010124A1 (en) * 1988-04-27 1989-11-02 Kievsky Nauchno-Issledovatelsky Institut Farmakolo Antidote for organic phosphorus compound poisoning
US5216170A (en) * 1989-01-26 1993-06-01 Bayer Aktiengesellschaft (2-aminopropyl) pyridines useful as intermediates
KR100498005B1 (ko) * 2002-07-26 2005-07-01 주식회사 소하드 기능성 액상비료 및 그 제조방법
JP4426527B2 (ja) * 2002-12-20 2010-03-03 エクソンモービル・ケミカル・パテンツ・インク 重合プロセス
US7443103B2 (en) * 2005-06-24 2008-10-28 General Electric Company High pressure lamp with lamp flicker suppression and lamp voltage control
WO2010003976A1 (en) * 2008-07-10 2010-01-14 Novartis Ag Cyclic sulfones with aminobenzyl substitution useful as bace inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN146736B (de) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4227000A (en) * 1978-04-11 1980-10-07 Smith Kline & French Laboratories Limited Intermediates in the process for making histamine antagonists
IL57416A (en) * 1978-05-30 1983-03-31 Smith Kline French Lab Nitro compounds,processes for preparing them and compositions containing them
US4255428A (en) * 1979-03-24 1981-03-10 Smith Kline & French Laboratories Limited 5-(Hydroxypyridylalkyl)-4-pyrimidones
JPS55133379A (en) * 1979-04-05 1980-10-17 Smith Kline French Lab Pyrimidone compound
EP0017680B1 (de) * 1979-04-11 1982-04-21 Smith Kline & French Laboratories Limited Pyrimidon-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
JPS55145683A (en) * 1979-04-26 1980-11-13 Smith Kline French Lab Pyrimidone derivative

Also Published As

Publication number Publication date
IL66125A (en) 1986-01-31
PL237110A1 (en) 1983-06-20
ES8305755A1 (es) 1983-05-01
DD202291A5 (de) 1983-09-07
FI822281A0 (fi) 1982-06-24
ATE22891T1 (de) 1986-11-15
EP0068833A2 (de) 1983-01-05
IL66125A0 (en) 1982-09-30
HU190396B (en) 1986-08-28
IE53348B1 (en) 1988-10-26
JO1185B1 (en) 1983-11-30
EP0068834A3 (en) 1983-04-06
PL137627B1 (en) 1986-07-31
ATE21900T1 (de) 1986-09-15
ES513469A0 (es) 1983-05-01
ZW13082A1 (en) 1982-09-29
JPS588080A (ja) 1983-01-18
DE3273782D1 (en) 1986-11-20
JPS6328424B2 (de) 1988-06-08
US4584381A (en) 1986-04-22
DK286982A (da) 1982-12-28
US4535163A (en) 1985-08-13
GR74926B (de) 1984-07-12
DK287082A (da) 1982-12-28
SU1232145A3 (ru) 1986-05-15
JPS61233670A (ja) 1986-10-17
KR840000533A (ko) 1984-02-25
YU138982A (en) 1985-03-20
EP0068834A2 (de) 1983-01-05
GR74925B (de) 1984-07-12
CS480082A2 (en) 1985-06-13
PT75074B (en) 1986-02-26
AU8535182A (en) 1983-01-06
PL240628A1 (en) 1983-10-10
AU551066B2 (en) 1986-04-17
IE821533L (en) 1982-12-27
PT75074A (en) 1982-07-01
JPS588079A (ja) 1983-01-18
KR880001475B1 (ko) 1988-08-13
DE3273019D1 (en) 1986-10-09
NZ201077A (en) 1985-09-13
AU8535282A (en) 1983-01-06
US4444772A (en) 1984-04-24
ZA824580B (en) 1983-05-25
PH19680A (en) 1986-06-13
PL138524B1 (en) 1986-09-30
PL137600B1 (en) 1986-07-31
CS241036B2 (en) 1986-03-13
JPH0244812B2 (de) 1990-10-05
EP0068833B1 (de) 1986-10-15
US4486434A (en) 1984-12-04
EP0068834B1 (de) 1986-09-03
JPS61233616A (ja) 1986-10-17
FI822281L (fi) 1982-12-28
NO822120L (no) 1982-12-28
EP0068833A3 (en) 1983-03-30
JPH0345073B2 (de) 1991-07-09
BG38163A3 (en) 1985-10-15

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