ES8202811A1 - Un procedimiento para la preparacion de derivados de benzo (1,4) dioxina - Google Patents

Un procedimiento para la preparacion de derivados de benzo (1,4) dioxina

Info

Publication number
ES8202811A1
ES8202811A1 ES502003A ES502003A ES8202811A1 ES 8202811 A1 ES8202811 A1 ES 8202811A1 ES 502003 A ES502003 A ES 502003A ES 502003 A ES502003 A ES 502003A ES 8202811 A1 ES8202811 A1 ES 8202811A1
Authority
ES
Spain
Prior art keywords
benzodioxines
therapy
processes
preparation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502003A
Other languages
English (en)
Other versions
ES502003A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Europeen de Recherches Mauvernay CERM
Original Assignee
Centre Europeen de Recherches Mauvernay CERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Europeen de Recherches Mauvernay CERM filed Critical Centre Europeen de Recherches Mauvernay CERM
Publication of ES502003A0 publication Critical patent/ES502003A0/es
Publication of ES8202811A1 publication Critical patent/ES8202811A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE DEIRVADOS DE BENZO (1,4) DIOXINA. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) EN QUE HAL ES HALOGENO (PREFERIBLEMENTE CLORO), CON EL COMPUESTO (III) O UNA SAL DE ADICION DEL MISMO. SE OBTIENE EL COMPUESTO (III) EL CUAL PUEDE TRANSFORMARSE EN LA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE. EN DICHO COMPUESTO (III), X ES HIDROGENO, ALQUILO DE 1 A 4 ATOMOS DE CARBONO, ALCOXI O TRIFUORMETILO.
ES502003A 1980-05-07 1981-05-07 Un procedimiento para la preparacion de derivados de benzo (1,4) dioxina Expired ES8202811A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8010223A FR2482101A1 (fr) 1980-05-07 1980-05-07 2-methanol a-aminomethyl benzo (1,4) dioxines, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES502003A0 ES502003A0 (es) 1982-03-01
ES8202811A1 true ES8202811A1 (es) 1982-03-01

Family

ID=9241732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502003A Expired ES8202811A1 (es) 1980-05-07 1981-05-07 Un procedimiento para la preparacion de derivados de benzo (1,4) dioxina

Country Status (8)

Country Link
EP (1) EP0039646A1 (es)
JP (1) JPS57500510A (es)
DK (1) DK417481A (es)
ES (1) ES8202811A1 (es)
FR (1) FR2482101A1 (es)
IE (1) IE810992L (es)
WO (1) WO1981003172A1 (es)
ZA (1) ZA812948B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0367888A1 (en) * 1988-11-08 1990-05-16 ISTITUTO LUSO FARMACO D'ITALIA S.p.A. 2,2-Disubstituted 2,3-dihydro-1,4-benzodioxin derivatives having hypotensive activity
WO1998025617A1 (en) * 1996-12-13 1998-06-18 Merck & Co., Inc. Substituted aryl piperazines as modulators of chemokine receptor activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038333A (en) * 1963-02-13 1966-08-10 Ici Ltd Pharmaceutical compositions
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
DE2325633A1 (de) * 1973-05-21 1974-12-12 Boehringer Sohn Ingelheim Piperazinderivate

Also Published As

Publication number Publication date
IE810992L (en) 1981-11-07
ES502003A0 (es) 1982-03-01
FR2482101B1 (es) 1983-05-27
JPS57500510A (es) 1982-03-25
FR2482101A1 (fr) 1981-11-13
ZA812948B (en) 1982-05-26
DK417481A (da) 1982-01-08
EP0039646A1 (fr) 1981-11-11
WO1981003172A1 (fr) 1981-11-12

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