ZA201309687B - Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom - Google Patents

Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom

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Publication number
ZA201309687B
ZA201309687B ZA2013/09687A ZA201309687A ZA201309687B ZA 201309687 B ZA201309687 B ZA 201309687B ZA 2013/09687 A ZA2013/09687 A ZA 2013/09687A ZA 201309687 A ZA201309687 A ZA 201309687A ZA 201309687 B ZA201309687 B ZA 201309687B
Authority
ZA
South Africa
Prior art keywords
imidazoquinolin
hydrazino
amines
made therefrom
conjugates made
Prior art date
Application number
ZA2013/09687A
Other languages
English (en)
Inventor
Paul D Wightman
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of ZA201309687B publication Critical patent/ZA201309687B/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
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    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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  • Biochemistry (AREA)
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  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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ZA2013/09687A 2011-06-03 2013-12-20 Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom ZA201309687B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493051P 2011-06-03 2011-06-03
US201161493143P 2011-06-03 2011-06-03
PCT/US2012/040461 WO2012167081A1 (en) 2011-06-03 2012-06-01 Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom

Publications (1)

Publication Number Publication Date
ZA201309687B true ZA201309687B (en) 2015-05-27

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Country Status (10)

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US (3) US9107958B2 (enExample)
EP (3) EP3153180A1 (enExample)
JP (3) JP6415979B2 (enExample)
CN (1) CN103582640B (enExample)
AU (1) AU2012261959B2 (enExample)
BR (1) BR112013031039B1 (enExample)
CA (1) CA2838023C (enExample)
MX (1) MX355623B (enExample)
WO (1) WO2012167081A1 (enExample)
ZA (1) ZA201309687B (enExample)

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RS55819B1 (sr) 2010-08-17 2017-08-31 3M Innovative Properties Co Kompozicije sa lipidiranim modifikatorom imuno-odgovora, formulacije, i postupci
MX355623B (es) * 2011-06-03 2018-04-25 3M Innovative Properties Co Hidrazino-1h-imidazoquinolin-4-aminas y conjugados elaborados a partir de las mismas.
MX347240B (es) 2011-06-03 2017-04-20 3M Innovative Properties Co Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos.
PE20151747A1 (es) 2013-03-14 2015-12-18 Univ Massachusetts Metodo para inhibir cataratas y presbicia
EP3033056B1 (en) 2013-08-12 2020-01-15 3M Innovative Properties Company Peptides for enhancing transdermal delivery
CN105873587B (zh) 2013-11-05 2020-07-21 3M创新有限公司 基于芝麻油的注射配制品
AR100137A1 (es) 2014-04-22 2016-09-14 Hoffmann La Roche Compuestos 4-amino-imidazoquinolina
PE20171456A1 (es) 2015-03-06 2017-10-06 Hoffmann La Roche Compuestos de dicarboxamida de benzazepinas
WO2016183371A1 (en) 2015-05-13 2016-11-17 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for the treatment or prevention of ischemic tissue damage
JP6893501B2 (ja) 2015-09-17 2021-06-23 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト スルフィニルフェニル又はスルホンイミドイルフェニルベンザゼピン
EP3356371A4 (en) * 2015-09-29 2020-06-24 The University of Chicago POLYMER CONJUGATE VACCINES
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CN109311851B (zh) 2016-06-12 2021-08-10 豪夫迈·罗氏有限公司 二氢嘧啶基苯并氮杂䓬甲酰胺化合物
AU2017292934B9 (en) 2016-07-07 2024-08-29 Bolt Biotherapeutics, Inc. Antibody adjuvant conjugates
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WO2019047824A1 (zh) * 2017-09-05 2019-03-14 浙江海正药业股份有限公司 新型咪唑喹啉化合物及其制备方法和用途
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