JP6415979B2 - ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体 - Google Patents

ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体 Download PDF

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JP6415979B2
JP6415979B2 JP2014513746A JP2014513746A JP6415979B2 JP 6415979 B2 JP6415979 B2 JP 6415979B2 JP 2014513746 A JP2014513746 A JP 2014513746A JP 2014513746 A JP2014513746 A JP 2014513746A JP 6415979 B2 JP6415979 B2 JP 6415979B2
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JP2014515406A5 (enExample
JP2014515406A (ja
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ディー．ワイトマン ポール
ディー．ワイトマン ポール
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3M Innovative Properties Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
JP2014513746A 2011-06-03 2012-06-01 ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体 Active JP6415979B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161493051P 2011-06-03 2011-06-03
US201161493143P 2011-06-03 2011-06-03
US61/493,143 2011-06-03
US61/493,051 2011-06-03
PCT/US2012/040461 WO2012167081A1 (en) 2011-06-03 2012-06-01 Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017078814A Division JP6430574B2 (ja) 2011-06-03 2017-04-12 ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体

Publications (3)

Publication Number Publication Date
JP2014515406A JP2014515406A (ja) 2014-06-30
JP2014515406A5 JP2014515406A5 (enExample) 2015-07-23
JP6415979B2 true JP6415979B2 (ja) 2018-10-31

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JP2014513746A Active JP6415979B2 (ja) 2011-06-03 2012-06-01 ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体
JP2017078814A Expired - Fee Related JP6430574B2 (ja) 2011-06-03 2017-04-12 ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体
JP2017078817A Pending JP2017160220A (ja) 2011-06-03 2017-04-12 ポリエチレングリコールセグメントを有するヘテロ２官能性リンカー及び該リンカーから調製された免疫反応調節複合体

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JP2017078814A Expired - Fee Related JP6430574B2 (ja) 2011-06-03 2017-04-12 ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体
JP2017078817A Pending JP2017160220A (ja) 2011-06-03 2017-04-12 ポリエチレングリコールセグメントを有するヘテロ２官能性リンカー及び該リンカーから調製された免疫反応調節複合体

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US (3) US9107958B2 (enExample)
EP (3) EP3153180A1 (enExample)
JP (3) JP6415979B2 (enExample)
CN (1) CN103582640B (enExample)
AU (1) AU2012261959B2 (enExample)
BR (1) BR112013031039B1 (enExample)
CA (1) CA2838023C (enExample)
MX (1) MX355623B (enExample)
WO (1) WO2012167081A1 (enExample)
ZA (1) ZA201309687B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871782B2 (en) 2003-10-03 2014-10-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
US8541438B2 (en) 2004-06-18 2013-09-24 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
RS55819B1 (sr) 2010-08-17 2017-08-31 3M Innovative Properties Co Kompozicije sa lipidiranim modifikatorom imuno-odgovora, formulacije, i postupci
MX355623B (es) * 2011-06-03 2018-04-25 3M Innovative Properties Co Hidrazino-1h-imidazoquinolin-4-aminas y conjugados elaborados a partir de las mismas.
MX347240B (es) 2011-06-03 2017-04-20 3M Innovative Properties Co Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos.
PE20151747A1 (es) 2013-03-14 2015-12-18 Univ Massachusetts Metodo para inhibir cataratas y presbicia
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US9107958B2 (en) 2015-08-18
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