ZA201204135B - 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4.3-c]isoquinoline derivatives - Google Patents
3,4,4a,10b-tetrahydro-1h-thiopyrano-[4.3-c]isoquinoline derivativesInfo
- Publication number
- ZA201204135B ZA201204135B ZA2012/04135A ZA201204135A ZA201204135B ZA 201204135 B ZA201204135 B ZA 201204135B ZA 2012/04135 A ZA2012/04135 A ZA 2012/04135A ZA 201204135 A ZA201204135 A ZA 201204135A ZA 201204135 B ZA201204135 B ZA 201204135B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiopyrano
- tetrahydro
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
- ZQCSTHXMOLTGJA-UHFFFAOYSA-N 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isoquinoline Chemical class N1=CC2=CC=CC=C2C2C1CCSC2 ZQCSTHXMOLTGJA-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179982 | 2009-12-18 | ||
| US31555210P | 2010-03-19 | 2010-03-19 | |
| PCT/EP2010/069704 WO2011073231A1 (en) | 2009-12-18 | 2010-12-15 | 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201204135B true ZA201204135B (en) | 2013-03-27 |
Family
ID=41718903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/04135A ZA201204135B (en) | 2009-12-18 | 2012-06-06 | 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4.3-c]isoquinoline derivatives |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9018175B2 (enExample) |
| EP (2) | EP2513119B1 (enExample) |
| JP (1) | JP5645961B2 (enExample) |
| KR (1) | KR20120123313A (enExample) |
| CN (1) | CN102652136B (enExample) |
| AR (1) | AR079451A1 (enExample) |
| AU (1) | AU2010332955B8 (enExample) |
| BR (1) | BR112012014058A8 (enExample) |
| CA (1) | CA2784013A1 (enExample) |
| CO (1) | CO6551705A2 (enExample) |
| DK (1) | DK2513119T3 (enExample) |
| EA (1) | EA023212B1 (enExample) |
| ES (2) | ES2621291T3 (enExample) |
| GE (1) | GEP20146105B (enExample) |
| HR (1) | HRP20140893T1 (enExample) |
| ME (1) | ME01914B (enExample) |
| MX (1) | MX2012006696A (enExample) |
| NZ (1) | NZ601115A (enExample) |
| PH (1) | PH12012501125A1 (enExample) |
| PL (1) | PL2513119T3 (enExample) |
| PT (1) | PT2513119E (enExample) |
| RS (1) | RS53544B1 (enExample) |
| SG (2) | SG196785A1 (enExample) |
| SI (1) | SI2513119T1 (enExample) |
| SM (1) | SMT201400185B (enExample) |
| TW (1) | TWI468411B (enExample) |
| UA (1) | UA107689C2 (enExample) |
| WO (1) | WO2011073231A1 (enExample) |
| ZA (1) | ZA201204135B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101930561B1 (ko) | 2010-06-07 | 2018-12-18 | 사푸라스트 리써치 엘엘씨 | 재충전 가능한 고밀도 전기 화학 장치 |
| CA2827045A1 (en) * | 2011-02-17 | 2012-08-23 | Cipla Limited | Compositions of glycopyrrolate and a beta2-agonist |
| US20140113877A1 (en) | 2011-06-15 | 2014-04-24 | Takeda Gmbh | Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c] isoquinoline compounds |
| WO2014016548A2 (en) * | 2012-07-27 | 2014-01-30 | Cipla Limited | Pharmaceutical composition |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
| WO2014117947A1 (en) | 2013-02-04 | 2014-08-07 | Grünenthal GmbH | 4-amino substituted condensed pyrimidine compounds as pde4 inhibitors |
| AP2015008663A0 (en) | 2013-02-19 | 2015-08-31 | Pfizer | Azabenzimidazole compounds as inhibitors of PDE4 isozymes for the treatment of cns and other disorders |
| EP3172210B1 (en) | 2014-07-24 | 2020-01-15 | Pfizer Inc | Pyrazolopyrimidine compounds |
| SG11201700243YA (en) | 2014-08-06 | 2017-02-27 | Pfizer | Imidazopyridazine compounds |
| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
| WO2022006470A1 (en) | 2020-07-01 | 2022-01-06 | Vanderbilt University | Methods of treatment for a kidney disease |
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| US3899494A (en) | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
| DE2047465A1 (de) | 1970-09-26 | 1972-03-30 | Farbwerke Hoechst AG, vorm Meister Lucius & Bruning, 6000 Frankfurt | Neue Oxdiazole und Verfahren zu lh rer Herstellung |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| JPH01213284A (ja) | 1988-02-22 | 1989-08-28 | Sankyo Co Ltd | チエノピリミジン−２，４−ジオン誘導体 |
| GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
| ES2060040T5 (es) | 1989-05-31 | 1999-09-16 | Fisons Plc | Dispositivo y formulacion de inhalacion de medicamento. |
| GB8921222D0 (en) | 1989-09-20 | 1989-11-08 | Riker Laboratories Inc | Medicinal aerosol formulations |
| IE67185B1 (en) | 1990-02-02 | 1996-03-06 | Fisons Plc | Propellant compositions |
| DE4003272A1 (de) | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
| CA2077354A1 (en) | 1990-03-23 | 1991-09-24 | Minnesota Mining And Manufacturing Company | Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
| AU658854B2 (en) | 1990-10-18 | 1995-05-04 | Minnesota Mining And Manufacturing Company | Aerosol formulation comprising beclomethasone 17,21 dipropionate |
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| IL104068A (en) | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
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| DE60024992T2 (de) | 1999-04-23 | 2006-08-24 | Battelle Memorial Institute, Columbus | Richtungsverstellbarer ehd- aerosol-zerstäuber |
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| CN1414951A (zh) | 1999-10-28 | 2003-04-30 | 基本治疗公司 | 药剂排出泵抑制药 |
| AU2001281802A1 (en) | 2000-06-07 | 2001-12-17 | Almirall Prodesfarma, S.A. | 6-phenylpyrrolopyrimidinedione derivatives |
| AU2001281965A1 (en) | 2000-07-14 | 2002-01-30 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Novel 6-phenylphenanthridines |
| ATE320242T1 (de) | 2000-10-09 | 2006-04-15 | 3M Innovative Properties Co | Medizinische aerosolzusammensetzung |
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| GB0202254D0 (en) | 2002-01-31 | 2002-03-20 | Pfizer Ltd | Prevention of scarring |
| AU2003253165A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidine fused bicyclic metalloproteinase inhibitors |
| WO2005102317A1 (en) | 2004-04-23 | 2005-11-03 | Celgene Corporation | Methods of using and compositions comprising pde4 modulators for the treatment and management of pulmonary hypertension |
| WO2006027345A2 (en) * | 2004-09-08 | 2006-03-16 | Altana Pharma Ag | Novel 3-thia-10-aza-phenanthrene derivatives |
| JP5009799B2 (ja) * | 2004-09-08 | 2012-08-22 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規の３−オキサ−１０−アザ−フェナントレン |
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| WO2006095009A1 (en) | 2005-03-09 | 2006-09-14 | Nycomed Gmbh | Amido-substituted 6-phenylphenanthridines |
| CA2684644A1 (en) * | 2007-04-23 | 2008-10-30 | Sanofi-Aventis | Quinoline-carboxamide derivatives as p2y12 antagonists |
| US20140113877A1 (en) * | 2011-06-15 | 2014-04-24 | Takeda Gmbh | Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c] isoquinoline compounds |
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