ME01914B - Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina - Google Patents

Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina

Info

Publication number
ME01914B
ME01914B MEP-2014-114A MEP11414A ME01914B ME 01914 B ME01914 B ME 01914B ME P11414 A MEP11414 A ME P11414A ME 01914 B ME01914 B ME 01914B
Authority
ME
Montenegro
Prior art keywords
tiopirano
izohinolina
derivati
test
Prior art date
Application number
MEP-2014-114A
Other languages
English (en)
Unknown language (me)
Inventor
Degenhard Marx
Clemens Braun
Dieter Flockerzi
Thomas Stengel
Alexander Mann
Harald Ohmer
Ulrich Kautz
Steffen Weinbrenner
Stefan Fischer
Christof Zitt
Armin Hatzelmann
Torsten Dunkern
Christian Hesslinger
Thomas Maier
Hermann Tenor
Raimund Külzer
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of ME01914B publication Critical patent/ME01914B/me

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
MEP-2014-114A 2009-12-18 2010-12-15 Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina ME01914B (me)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP09179982 2009-12-18
US31555210P 2010-03-19 2010-03-19
EP10790569.7A EP2513119B1 (en) 2009-12-18 2010-12-15 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinoline derivatives
PCT/EP2010/069704 WO2011073231A1 (en) 2009-12-18 2010-12-15 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
ME01914B true ME01914B (me) 2015-05-20

Family

ID=41718903

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2014-114A ME01914B (me) 2009-12-18 2010-12-15 Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina

Country Status (29)

Country Link
US (1) US9018175B2 (enExample)
EP (2) EP2813509B1 (enExample)
JP (1) JP5645961B2 (enExample)
KR (1) KR20120123313A (enExample)
CN (1) CN102652136B (enExample)
AR (1) AR079451A1 (enExample)
AU (1) AU2010332955B8 (enExample)
BR (1) BR112012014058A8 (enExample)
CA (1) CA2784013A1 (enExample)
CO (1) CO6551705A2 (enExample)
DK (1) DK2513119T3 (enExample)
EA (1) EA023212B1 (enExample)
ES (2) ES2621291T3 (enExample)
GE (1) GEP20146105B (enExample)
HR (1) HRP20140893T1 (enExample)
ME (1) ME01914B (enExample)
MX (1) MX2012006696A (enExample)
NZ (1) NZ601115A (enExample)
PH (1) PH12012501125A1 (enExample)
PL (1) PL2513119T3 (enExample)
PT (1) PT2513119E (enExample)
RS (1) RS53544B1 (enExample)
SG (2) SG196785A1 (enExample)
SI (1) SI2513119T1 (enExample)
SM (1) SMT201400185B (enExample)
TW (1) TWI468411B (enExample)
UA (1) UA107689C2 (enExample)
WO (1) WO2011073231A1 (enExample)
ZA (1) ZA201204135B (enExample)

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WO2014016548A2 (en) * 2012-07-27 2014-01-30 Cipla Limited Pharmaceutical composition
US20150322049A1 (en) * 2012-12-13 2015-11-12 Ludwig Aigner Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease
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WO2016012896A1 (en) 2014-07-24 2016-01-28 Pfizer Inc. Pyrazolopyrimidine compounds
EA031201B1 (ru) 2014-08-06 2018-11-30 Пфайзер Инк. Соединения имидазопиридазина
WO2017089347A1 (en) 2015-11-25 2017-06-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas
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