BR112012014058A2 - derivados de 3,4,4a,10b- tetraidro-1h- tiopirano[4,3-c]isoquinolina - Google Patents
derivados de 3,4,4a,10b- tetraidro-1h- tiopirano[4,3-c]isoquinolinaInfo
- Publication number
- BR112012014058A2 BR112012014058A2 BR112012014058A BR112012014058A BR112012014058A2 BR 112012014058 A2 BR112012014058 A2 BR 112012014058A2 BR 112012014058 A BR112012014058 A BR 112012014058A BR 112012014058 A BR112012014058 A BR 112012014058A BR 112012014058 A2 BR112012014058 A2 BR 112012014058A2
- Authority
- BR
- Brazil
- Prior art keywords
- thiopyran
- tetrahydro
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179982 | 2009-12-18 | ||
| US31555210P | 2010-03-19 | 2010-03-19 | |
| PCT/EP2010/069704 WO2011073231A1 (en) | 2009-12-18 | 2010-12-15 | 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112012014058A2 true BR112012014058A2 (pt) | 2017-10-24 |
| BR112012014058A8 BR112012014058A8 (pt) | 2018-02-06 |
Family
ID=41718903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012014058A BR112012014058A8 (pt) | 2009-12-18 | 2010-12-15 | Derivados de 3,4,4a,10b- tetraidro-1h- tiopirano[4,3-c]isoquinolina |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9018175B2 (pt) |
| EP (2) | EP2513119B1 (pt) |
| JP (1) | JP5645961B2 (pt) |
| KR (1) | KR20120123313A (pt) |
| CN (1) | CN102652136B (pt) |
| AR (1) | AR079451A1 (pt) |
| AU (1) | AU2010332955B8 (pt) |
| BR (1) | BR112012014058A8 (pt) |
| CA (1) | CA2784013A1 (pt) |
| CO (1) | CO6551705A2 (pt) |
| DK (1) | DK2513119T3 (pt) |
| EA (1) | EA023212B1 (pt) |
| ES (2) | ES2621291T3 (pt) |
| GE (1) | GEP20146105B (pt) |
| HK (1) | HK1174326A1 (pt) |
| HR (1) | HRP20140893T1 (pt) |
| ME (1) | ME01914B (pt) |
| MX (1) | MX2012006696A (pt) |
| NZ (1) | NZ601115A (pt) |
| PL (1) | PL2513119T3 (pt) |
| PT (1) | PT2513119E (pt) |
| RS (1) | RS53544B1 (pt) |
| SG (2) | SG180824A1 (pt) |
| SI (1) | SI2513119T1 (pt) |
| SM (1) | SMT201400185B (pt) |
| TW (1) | TWI468411B (pt) |
| UA (1) | UA107689C2 (pt) |
| WO (1) | WO2011073231A1 (pt) |
| ZA (1) | ZA201204135B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110300432A1 (en) | 2010-06-07 | 2011-12-08 | Snyder Shawn W | Rechargeable, High-Density Electrochemical Device |
| EP2749283A3 (en) * | 2011-02-17 | 2014-08-20 | Cipla Limited | Combination of glycopyrronium and olodaterol |
| JP2014519519A (ja) * | 2011-06-15 | 2014-08-14 | タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規３，４，４ａ，１０ｂ−テトラヒドロ−１Ｈ−チオピラノ［４，３−ｃ］イソキノリン化合物 |
| WO2014016548A2 (en) * | 2012-07-27 | 2014-01-30 | Cipla Limited | Pharmaceutical composition |
| US20150322049A1 (en) * | 2012-12-13 | 2015-11-12 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
| WO2014117947A1 (en) | 2013-02-04 | 2014-08-07 | Grünenthal GmbH | 4-amino substituted condensed pyrimidine compounds as pde4 inhibitors |
| EP2958915B1 (en) | 2013-02-19 | 2017-07-05 | Pfizer Inc | Azabenzimidazole compounds as inhibitors of pde4 isozymes for the treatment of cns and other disorders |
| WO2016012896A1 (en) | 2014-07-24 | 2016-01-28 | Pfizer Inc. | Pyrazolopyrimidine compounds |
| JP6506833B2 (ja) | 2014-08-06 | 2019-04-24 | ファイザー・インク | イミダゾピリダジン化合物 |
| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
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| DE2047465A1 (de) | 1970-09-26 | 1972-03-30 | Farbwerke Hoechst AG, vorm Meister Lucius & Bruning, 6000 Frankfurt | Neue Oxdiazole und Verfahren zu lh rer Herstellung |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| JPH01213284A (ja) | 1988-02-22 | 1989-08-28 | Sankyo Co Ltd | チエノピリミジン−２，４−ジオン誘導体 |
| GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
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| GB8921222D0 (en) | 1989-09-20 | 1989-11-08 | Riker Laboratories Inc | Medicinal aerosol formulations |
| IL97065A (en) | 1990-02-02 | 1994-01-25 | Fisons Plc | Repellent preparations for aerosol |
| DE4003272A1 (de) | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
| DE69109284T2 (de) | 1990-03-23 | 1995-08-24 | Minnesota Mining & Mfg | Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe. |
| ES2064160T3 (es) | 1990-10-18 | 1995-01-16 | Minnesota Mining & Mfg | Formulacion de aerosol que comprende 17,21-dipropionato de beclometasona. |
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| GB9213874D0 (en) | 1992-06-30 | 1992-08-12 | Fisons Plc | Process to novel medicament form |
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| JP5009799B2 (ja) * | 2004-09-08 | 2012-08-22 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規の３−オキサ−１０−アザ−フェナントレン |
| WO2006027345A2 (en) * | 2004-09-08 | 2006-03-16 | Altana Pharma Ag | Novel 3-thia-10-aza-phenanthrene derivatives |
| WO2006054560A1 (ja) | 2004-11-17 | 2006-05-26 | Kissei Pharmaceutical Co., Ltd. | 芳香族アミド誘導体、それを含有する医薬組成物およびそれらの医薬用途 |
| EA200701813A1 (ru) * | 2005-03-09 | 2008-06-30 | Никомед Гмбх | Новые амидозамещенные 6-фенилфенантридины |
| EP2148871A1 (en) | 2007-04-23 | 2010-02-03 | Sanofi-Aventis | Quinoline-carboxamide derivatives as p2y12 antagonists |
| JP2014519519A (ja) * | 2011-06-15 | 2014-08-14 | タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規３，４，４ａ，１０ｂ−テトラヒドロ−１Ｈ−チオピラノ［４，３−ｃ］イソキノリン化合物 |
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