ZA200806277B - Triazolopyridazines as tyrosine kinase modulators - Google Patents

Triazolopyridazines as tyrosine kinase modulators

Info

Publication number
ZA200806277B
ZA200806277B ZA200806277A ZA200806277A ZA200806277B ZA 200806277 B ZA200806277 B ZA 200806277B ZA 200806277 A ZA200806277 A ZA 200806277A ZA 200806277 A ZA200806277 A ZA 200806277A ZA 200806277 B ZA200806277 B ZA 200806277B
Authority
ZA
South Africa
Prior art keywords
triazolopyridazines
tyrosine kinase
kinase modulators
modulators
tyrosine
Prior art date
Application number
ZA200806277A
Other languages
English (en)
Inventor
Tianbao Lu
Richard W Connors
Robert A Galemmo
Dana L Johnson
Kristi A Leonard
Anna C Maroney
Jeremy M Travins
Richard Alexander
Maxwell D Cummings
Heather Rae Hufnagel
Ehab Khalil
Thoman P Markotan
Jan L Sechler
Robert W Tuman
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37964498&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200806277(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA200806277B publication Critical patent/ZA200806277B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Materials For Medical Uses (AREA)
ZA200806277A 2005-12-21 2008-07-18 Triazolopyridazines as tyrosine kinase modulators ZA200806277B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75263405P 2005-12-21 2005-12-21

Publications (1)

Publication Number Publication Date
ZA200806277B true ZA200806277B (en) 2010-09-29

Family

ID=37964498

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200806277A ZA200806277B (en) 2005-12-21 2008-07-18 Triazolopyridazines as tyrosine kinase modulators

Country Status (40)

Country Link
US (2) US8030305B2 (fr)
EP (1) EP1966214B9 (fr)
JP (1) JP5292102B2 (fr)
KR (1) KR101412675B1 (fr)
CN (1) CN101374843B (fr)
AP (1) AP3433A (fr)
AR (1) AR058703A1 (fr)
AU (1) AU2006331912B2 (fr)
BR (1) BRPI0620292B1 (fr)
CA (1) CA2634721C (fr)
CR (1) CR10170A (fr)
CY (1) CY1118846T1 (fr)
DK (1) DK1966214T3 (fr)
EA (1) EA015754B1 (fr)
EC (1) ECSP088573A (fr)
ES (1) ES2612377T3 (fr)
GT (1) GT200800105A (fr)
HN (1) HN2008000931A (fr)
HR (1) HRP20170103T1 (fr)
HU (1) HUE030390T2 (fr)
IL (1) IL192108A (fr)
LT (1) LT1966214T (fr)
MA (1) MA30084B1 (fr)
ME (1) ME02736B (fr)
MX (1) MX2008008277A (fr)
MY (1) MY159523A (fr)
NI (1) NI200800179A (fr)
NO (1) NO340958B1 (fr)
NZ (1) NZ568807A (fr)
PE (2) PE20110008A1 (fr)
PL (1) PL1966214T3 (fr)
PT (1) PT1966214T (fr)
RS (1) RS55630B1 (fr)
SV (1) SV2008002963A (fr)
TN (1) TNSN08278A1 (fr)
TW (1) TWI399378B (fr)
UA (1) UA98297C2 (fr)
UY (1) UY30041A1 (fr)
WO (1) WO2007075567A1 (fr)
ZA (1) ZA200806277B (fr)

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