ZA200601231B - Modified human IGF-1R anbitodies - Google Patents

Modified human IGF-1R anbitodies Download PDF

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Publication number
ZA200601231B
ZA200601231B ZA200601231A ZA200601231A ZA200601231B ZA 200601231 B ZA200601231 B ZA 200601231B ZA 200601231 A ZA200601231 A ZA 200601231A ZA 200601231 A ZA200601231 A ZA 200601231A ZA 200601231 B ZA200601231 B ZA 200601231B
Authority
ZA
South Africa
Prior art keywords
antibody
igf
human
antigen
binding portion
Prior art date
Application number
ZA200601231A
Other languages
English (en)
Inventor
Cohen Bruce David
Bedian Vahe
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200601231B publication Critical patent/ZA200601231B/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200601231A 2003-08-13 2006-02-10 Modified human IGF-1R anbitodies ZA200601231B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49520003P 2003-08-13 2003-08-13

Publications (1)

Publication Number Publication Date
ZA200601231B true ZA200601231B (en) 2007-05-30

Family

ID=34193291

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200601231A ZA200601231B (en) 2003-08-13 2006-02-10 Modified human IGF-1R anbitodies

Country Status (37)

Country Link
US (2) US7371378B2 (zh)
EP (1) EP1656391B1 (zh)
JP (1) JP4638870B2 (zh)
KR (1) KR100825156B1 (zh)
CN (1) CN1835975B (zh)
AP (1) AP2006003510A0 (zh)
AR (1) AR045247A1 (zh)
AT (1) ATE484525T1 (zh)
AU (1) AU2004265152A1 (zh)
BR (1) BRPI0413466A (zh)
CA (1) CA2535071A1 (zh)
CL (1) CL2004002035A1 (zh)
CR (1) CR8233A (zh)
DE (1) DE602004029581D1 (zh)
DK (1) DK1656391T3 (zh)
EA (1) EA200600234A1 (zh)
EC (1) ECSP066359A (zh)
ES (1) ES2351395T3 (zh)
GT (1) GT200400158A (zh)
IL (1) IL173273A (zh)
IS (1) IS8266A (zh)
MA (1) MA27988A1 (zh)
MX (1) MXPA06001634A (zh)
NL (1) NL1026829C2 (zh)
NO (1) NO20060542L (zh)
OA (1) OA13234A (zh)
PA (1) PA8608801A1 (zh)
PE (1) PE20050339A1 (zh)
PL (1) PL1656391T3 (zh)
PT (1) PT1656391E (zh)
RS (1) RS20060099A (zh)
TN (1) TNSN06050A1 (zh)
TW (1) TWI294915B (zh)
UA (1) UA85058C2 (zh)
UY (1) UY28464A1 (zh)
WO (1) WO2005016967A2 (zh)
ZA (1) ZA200601231B (zh)

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Also Published As

Publication number Publication date
ES2351395T3 (es) 2011-02-04
WO2005016967A2 (en) 2005-02-24
WO2005016967A3 (en) 2005-04-14
JP2007527705A (ja) 2007-10-04
DE602004029581D1 (de) 2010-11-25
NL1026829A1 (nl) 2005-02-15
ECSP066359A (es) 2006-10-31
MA27988A1 (fr) 2006-07-03
EP1656391B1 (en) 2010-10-13
NO20060542L (no) 2006-05-03
GT200400158A (es) 2005-07-22
RS20060099A (en) 2008-08-07
CR8233A (es) 2007-01-18
KR100825156B1 (ko) 2008-04-24
OA13234A (en) 2006-12-13
PT1656391E (pt) 2010-12-06
PL1656391T3 (pl) 2011-03-31
US7575746B2 (en) 2009-08-18
PA8608801A1 (es) 2005-03-03
UA85058C2 (ru) 2008-12-25
CN1835975A (zh) 2006-09-20
DK1656391T3 (da) 2011-01-03
EP1656391A2 (en) 2006-05-17
US20080181891A1 (en) 2008-07-31
CA2535071A1 (en) 2005-02-24
UY28464A1 (es) 2005-03-31
ATE484525T1 (de) 2010-10-15
US7371378B2 (en) 2008-05-13
IL173273A0 (en) 2006-06-11
IS8266A (is) 2006-01-26
US20050069539A1 (en) 2005-03-31
TW200516145A (en) 2005-05-16
EA200600234A1 (ru) 2006-08-25
NL1026829C2 (nl) 2005-07-05
MXPA06001634A (es) 2006-04-28
TWI294915B (en) 2008-03-21
CL2004002035A1 (es) 2005-06-03
BRPI0413466A (pt) 2006-10-17
KR20060035796A (ko) 2006-04-26
AU2004265152A1 (en) 2005-02-24
IL173273A (en) 2011-10-31
TNSN06050A1 (fr) 2007-10-03
PE20050339A1 (es) 2005-05-17
CN1835975B (zh) 2012-11-21
AR045247A1 (es) 2005-10-19
JP4638870B2 (ja) 2011-02-23
AP2006003510A0 (en) 2006-02-28

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