ZA200208898B - Adenosine A2A receptor antagonists. - Google Patents

Adenosine A2A receptor antagonists. Download PDF

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Publication number
ZA200208898B
ZA200208898B ZA200208898A ZA200208898A ZA200208898B ZA 200208898 B ZA200208898 B ZA 200208898B ZA 200208898 A ZA200208898 A ZA 200208898A ZA 200208898 A ZA200208898 A ZA 200208898A ZA 200208898 B ZA200208898 B ZA 200208898B
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ZA
South Africa
Prior art keywords
alkyl
alkoxy
compound
formula
mmol
Prior art date
Application number
ZA200208898A
Other languages
English (en)
Inventor
Craig D Boyle
Bernard R Neustadt
William J Greenlee
Lisa S Silverman
Neil A Lindo
Dean Tulshian
Yan Xia
Samuel Chackalamannil
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA200208898B publication Critical patent/ZA200208898B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200208898A 2000-05-26 2002-11-01 Adenosine A2A receptor antagonists. ZA200208898B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20714300P 2000-05-26 2000-05-26

Publications (1)

Publication Number Publication Date
ZA200208898B true ZA200208898B (en) 2004-03-01

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Family Applications (1)

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ZA200208898A ZA200208898B (en) 2000-05-26 2002-11-01 Adenosine A2A receptor antagonists.

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US (4) US6630475B2 (cs)
EP (1) EP1283839B1 (cs)
JP (3) JP4574112B2 (cs)
KR (1) KR100520907B1 (cs)
CN (2) CN100384847C (cs)
AR (1) AR028621A1 (cs)
AT (1) ATE293627T1 (cs)
AU (2) AU2001268089C1 (cs)
BR (1) BRPI0111015B8 (cs)
CA (1) CA2410237C (cs)
CZ (1) CZ303790B6 (cs)
DE (1) DE60110219T2 (cs)
DK (1) DK1283839T3 (cs)
EC (1) ECSP024364A (cs)
ES (1) ES2237576T3 (cs)
HK (1) HK1049007B (cs)
HU (1) HU230420B1 (cs)
IL (3) IL152726A0 (cs)
MX (1) MXPA02011625A (cs)
MY (1) MY132006A (cs)
NO (1) NO325008B1 (cs)
NZ (1) NZ522326A (cs)
PE (1) PE20020062A1 (cs)
PL (1) PL218764B1 (cs)
PT (1) PT1283839E (cs)
RU (1) RU2315053C2 (cs)
SI (1) SI1283839T1 (cs)
SK (1) SK287748B6 (cs)
TW (1) TWI288137B (cs)
WO (1) WO2001092264A1 (cs)
ZA (1) ZA200208898B (cs)

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CN100384847C (zh) 2008-04-30
CA2410237C (en) 2008-01-08
KR20030003746A (ko) 2003-01-10
BR0111015A (pt) 2005-01-11
CN1247588C (zh) 2006-03-29
JP2006219497A (ja) 2006-08-24
US6630475B2 (en) 2003-10-07
HUP0600239A2 (en) 2006-07-28
PT1283839E (pt) 2005-08-31
AU2001268089C1 (en) 2006-04-13
HK1049007A1 (en) 2003-04-25
US20020099061A1 (en) 2002-07-25
PL360472A1 (en) 2004-09-06
NO20025651D0 (no) 2002-11-25
EP1283839A1 (en) 2003-02-19
HUP0600239A3 (en) 2008-06-30
US20040023997A1 (en) 2004-02-05
KR100520907B1 (ko) 2005-10-11
JP4938348B2 (ja) 2012-05-23
CN1800186A (zh) 2006-07-12
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AU2001268089B2 (en) 2005-04-28
JP2003535094A (ja) 2003-11-25
AU6808901A (en) 2001-12-11
CZ303790B6 (cs) 2013-05-09
IL220174A0 (en) 2012-07-31
WO2001092264A1 (en) 2001-12-06
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NO325008B1 (no) 2008-01-14
ATE293627T1 (de) 2005-05-15
JP4574112B2 (ja) 2010-11-04
CZ20023886A3 (cs) 2003-02-12
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NO20025651L (no) 2003-01-23
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US20050026932A1 (en) 2005-02-03
PL218764B1 (pl) 2015-01-30
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ECSP024364A (es) 2003-03-31
BRPI0111015B1 (pt) 2017-11-07
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JP2007145875A (ja) 2007-06-14
HU230420B1 (hu) 2016-05-30
BRPI0111015B8 (pt) 2021-05-25
MY132006A (en) 2007-09-28
SK16712002A3 (sk) 2003-08-05
RU2315053C2 (ru) 2008-01-20
HK1049007B (en) 2005-09-16
DE60110219D1 (de) 2005-05-25
ES2237576T3 (es) 2005-08-01
SK287748B6 (sk) 2011-08-04
EP1283839B1 (en) 2005-04-20
US7067655B2 (en) 2006-06-27
USRE44205E1 (en) 2013-05-07
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US6897216B2 (en) 2005-05-24

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