ZA200004485B - Sustained release microparticle and method for preparing the same. - Google Patents

Sustained release microparticle and method for preparing the same.

Info

Publication number
ZA200004485B
ZA200004485B ZA200004485A ZA200004485A ZA200004485B ZA 200004485 B ZA200004485 B ZA 200004485B ZA 200004485 A ZA200004485 A ZA 200004485A ZA 200004485 A ZA200004485 A ZA 200004485A ZA 200004485 B ZA200004485 B ZA 200004485B
Authority
ZA
South Africa
Prior art keywords
preparing
same
sustained release
release microparticle
microparticle
Prior art date
Application number
ZA200004485A
Other languages
English (en)
Inventor
Jin Kyu Park
Mork Soon Park
Dong Seon Kim
Ii Ho Lim
Ung Kil Jee
Pyung Keun Myung
Sang Beom Kim
Goo Young Jung
Original Assignee
Dong Kook Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Kook Pharm Co Ltd filed Critical Dong Kook Pharm Co Ltd
Publication of ZA200004485B publication Critical patent/ZA200004485B/xx

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/64—Heating using microwaves
    • H05B6/80—Apparatus for specific applications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B40/00—Technologies aiming at improving the efficiency of home appliances, e.g. induction cooking or efficient technologies for refrigerators, freezers or dish washers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Glanulating (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
ZA200004485A 2000-06-28 2000-08-29 Sustained release microparticle and method for preparing the same. ZA200004485B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20000036178A KR100392501B1 (ko) 2000-06-28 2000-06-28 다중 에멀젼법에 의한 서방출성 미립구의 제조방법

Publications (1)

Publication Number Publication Date
ZA200004485B true ZA200004485B (en) 2001-02-28

Family

ID=19674602

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200004485A ZA200004485B (en) 2000-06-28 2000-08-29 Sustained release microparticle and method for preparing the same.

Country Status (16)

Country Link
US (1) US6506410B1 (enExample)
JP (1) JP3641418B2 (enExample)
KR (1) KR100392501B1 (enExample)
CN (1) CN1330921A (enExample)
BR (2) BRPI0005287B1 (enExample)
CA (1) CA2317769C (enExample)
DE (1) DE10045374B4 (enExample)
ES (1) ES2185460B1 (enExample)
FR (1) FR2810885B1 (enExample)
GB (1) GB2363986B (enExample)
IN (1) IN189017B (enExample)
IT (1) IT1320273B1 (enExample)
MX (1) MXPA00009408A (enExample)
PL (1) PL348343A1 (enExample)
TR (1) TR200003123A2 (enExample)
ZA (1) ZA200004485B (enExample)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003509478A (ja) * 1999-09-21 2003-03-11 エモリー・ユニバーシティ 血小板関連障害を処置する方法および組成物
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
DE60138641D1 (de) 2000-10-27 2009-06-18 Baxter Healthcare Sa Herstellung von mikrokügelchen
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
US20030064033A1 (en) * 2001-08-16 2003-04-03 Brown Larry R. Propellant-based microparticle formulations
GB0129489D0 (en) * 2001-12-10 2002-01-30 Quadrant Healthcare Uk Ltd Sustained-release compositions
CN1620285A (zh) * 2001-12-26 2005-05-25 武田药品工业株式会社 新微球和其生产方法
US20060064767A1 (en) * 2002-08-19 2006-03-23 Gen Sobue Nonhuman animal reproducing pathogenic conditions of spinal and bulbar muscular atrophy and remedy for spinal and bulbar muscular atrophy
WO2004058844A1 (ja) * 2002-12-25 2004-07-15 E-Tec Co., Ltd. 樹脂微粒子及び樹脂マイクロカプセル、並びにそれらの製造方法
DE10315640A1 (de) * 2003-04-04 2004-10-14 Ignatov, Konstantin Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
US20040210118A1 (en) * 2003-04-18 2004-10-21 Michel Letort In situ detection of endoleak and endotension
US20040213767A1 (en) * 2003-04-23 2004-10-28 Marc Hendriks Methods for using adipose-derived cells for healing of aortic aneurysmal tissue
US20040215318A1 (en) * 2003-04-24 2004-10-28 Brian Kwitkin Timed delivery of therapeutics to blood vessels
US20040215320A1 (en) * 2003-04-25 2004-10-28 James Machek Integral stent graft
US20040254629A1 (en) * 2003-04-25 2004-12-16 Brian Fernandes Methods and apparatus for treatment of aneurysmal tissue
US7387645B2 (en) * 2003-04-25 2008-06-17 Medtronic Vascular, Inc. Cellular therapy to heal vascular tissue
US7396540B2 (en) * 2003-04-25 2008-07-08 Medtronic Vascular, Inc. In situ blood vessel and aneurysm treatment
US20040215335A1 (en) * 2003-04-25 2004-10-28 Brin David S. Methods and apparatus for treatment of aneurysmal tissue
WO2004103425A1 (en) * 2003-05-23 2004-12-02 Gambro Lundia Ab Biocompatible polymer
SE526027C2 (sv) 2003-05-23 2005-06-14 Gambro Lundia Ab Biokompatibel polymerkomposition, förfarande för beredning av en biokompatibel sampolymerkomposition, artikel med en film av en polymerkomposition och användning av en biokompatibel polymerkomposition för en medicinsk anordning
US8075919B2 (en) * 2003-07-18 2011-12-13 Baxter International Inc. Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
WO2005009375A2 (en) * 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20050043786A1 (en) * 2003-08-18 2005-02-24 Medtronic Ave, Inc. Methods and apparatus for treatment of aneurysmal tissue
US7371228B2 (en) 2003-09-19 2008-05-13 Medtronic Vascular, Inc. Delivery of therapeutics to treat aneurysms
CN1314453C (zh) * 2003-09-25 2007-05-09 中国科学院过程工程研究所 尺寸均一、储存稳定的亲水性药物的复乳载体及其制备方法
TW200529890A (en) * 2004-02-10 2005-09-16 Takeda Pharmaceutical Sustained-release preparations
US7884085B2 (en) * 2004-05-12 2011-02-08 Baxter International Inc. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
CN103393601A (zh) 2004-05-12 2013-11-20 巴克斯特国际公司 含有蛋白并在高浓度蛋白下显示可注射性的微球体
EP1765294B1 (en) * 2004-05-12 2008-09-24 Baxter International Inc. Nucleic acid microspheres, production and delivery thereof
US20050266043A1 (en) * 2004-05-27 2005-12-01 Medtronic Vascular, Inc. Methods and compounds for treatment of aneurysmal tissue
US20050266042A1 (en) * 2004-05-27 2005-12-01 Medtronic Vascular, Inc. Methods and apparatus for treatment of aneurysmal tissue
US8048409B2 (en) * 2004-05-27 2011-11-01 Medtronic Vascular, Inc. Cellular therapy to heal vascular tissue
ES2432556T3 (es) * 2004-08-04 2013-12-04 Evonik Corporation Métodos para fabricar dispositivos de suministro y sus dispositivos
US9801913B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Barrier layer
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
MX2007013356A (es) * 2005-04-27 2008-03-26 Baxter Int Microparticulas modificadas en la superficie y metodos de formacion y uso de las mismas.
EP1933764A2 (en) * 2005-09-02 2008-06-25 Medtronic Vascular, Inc. Methods and apparatus for treatment of aneurysms adjacent to branch arteries
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
CN1939316B (zh) * 2005-09-28 2012-01-25 中国人民解放军军事医学科学院毒物药物研究所 含阿霉素的微球及其制备方法
US20080286375A1 (en) * 2005-11-15 2008-11-20 Amorepacific Corporation Method for Preparing Sustained-Release Microparticles Comprising Sucrose Acetate Isobutyrate
KR20130024988A (ko) * 2005-12-22 2013-03-08 노파르티스 아게 옥트레오티드 및 2종 이상의 폴리락티드-코-글리콜리드 중합체를 포함하는 서방형 제제
KR100722607B1 (ko) * 2006-05-11 2007-05-28 주식회사 펩트론 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
KR100801194B1 (ko) * 2006-07-14 2008-02-11 한국과학기술원 세포 배양 및 전달용 다공성 생분해성 고분자 미립 담체와그의 제조방법
AU2007281737B2 (en) 2006-08-04 2013-09-19 Baxter Healthcare S.A. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
ES2420479T3 (es) * 2006-08-31 2013-08-23 Sk Chemicals, Co., Ltd. Procedimiento para la producción de microesferas cargadas con fármacos y microesferas cargadas con fármacos producidas mediante el mismo
MX2009003661A (es) * 2006-10-06 2009-04-22 Baxter Int Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas.
KR100845009B1 (ko) 2007-08-07 2008-07-08 한국생명공학연구원 전하를 띠는 물질이 고착된 다공성 고분자 입자 및 그제조방법
JP2011503213A (ja) * 2007-11-19 2011-01-27 カプスレイテッド システムズ インコーポレイテッド マイクロ粒子を使用する局所麻酔薬の持続放出および手術適用方法
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
KR101005562B1 (ko) 2008-05-01 2011-01-05 한국생명공학연구원 난용성 약물을 함유하는 균일한 크기의 고분자 나노입자제조방법
US8697098B2 (en) * 2011-02-25 2014-04-15 South Dakota State University Polymer conjugated protein micelles
GB2460915B (en) * 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
KR100963435B1 (ko) * 2008-06-19 2010-06-17 한국과학기술연구원 서방형 약물전달 및 조직재생용 덮인 다공성 생분해성고분자 미립구의 제조 방법
US8034382B2 (en) * 2008-07-31 2011-10-11 The Board Of Trustees Of The University Of Arkansas Preparation method for biodegradable micro-particles containing drugs
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8323685B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US20100131001A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Targeted Drug Delivery for Aneurysm Treatment
US20100131051A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Systems and Methods for Treatment of Aneurysms Using Zinc Chelator(s)
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
CA2749993C (en) * 2009-01-23 2016-12-20 Surmodics Pharmaceuticals, Inc. Continuous double emulsion process for making microparticles
KR101663561B1 (ko) * 2009-02-18 2016-10-10 동국제약 주식회사 서방출성 미립구의 제조방법
CN101530396A (zh) * 2009-04-15 2009-09-16 西安力邦医药科技有限责任公司 氨氯地平微球的制备方法
KR101105292B1 (ko) 2009-06-05 2012-01-17 주식회사 리젠 바이오텍 생분해성 고분자 미세입자와 그의 제조방법
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
KR20120107070A (ko) * 2009-09-22 2012-09-28 에보닉 데구사 코포레이션 다양한 생리활성 물질 로딩 구성을 갖는 임플란트 장치
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US10322213B2 (en) 2010-07-16 2019-06-18 Atrium Medical Corporation Compositions and methods for altering the rate of hydrolysis of cured oil-based materials
KR101785515B1 (ko) * 2010-11-08 2017-10-16 에스케이케미칼주식회사 올란자핀 함유 고분자 미립구를 유효성분으로 포함하는 약학적 조성물
KR20120048811A (ko) * 2010-11-08 2012-05-16 에스케이케미칼주식회사 아나스트로졸 함유 고분자 미립구를 유효성분으로 포함하는 약학적 조성물
KR101411349B1 (ko) 2010-12-24 2014-06-25 주식회사 삼양바이오팜 생리활성 펩타이드를 포함하는 마이크로입자 및 그의 제조방법, 및 그를 포함하는 약제학적 조성물
CA2828253C (en) 2011-02-25 2016-10-18 South Dakota State University Polymer conjugated protein micelles
KR101481859B1 (ko) * 2011-05-20 2015-01-14 에스케이케미칼주식회사 초기 약물 방출이 감소된 고분자 미립자의 제조방법 및 그 방법에 의해 제조된 고분자 미립자
CN102389756B (zh) * 2011-08-11 2014-01-01 长春金赛药业有限责任公司 复乳法制备微球的方法
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
HK1221405A1 (zh) 2013-04-05 2017-06-02 Claudia Zylberberg 基质金属蛋白酶及其用途
CN103211773B (zh) * 2013-04-10 2014-11-05 上海丽珠制药有限公司 一种制备醋酸亮丙瑞林微球的方法
KR101543507B1 (ko) * 2013-05-15 2015-08-11 씨제이헬스케어 주식회사 연속 공정의 미립구의 제조 방법 및 이로부터 제조된 미립구
CN103724635B (zh) * 2013-12-06 2016-01-20 中国烟草总公司郑州烟草研究院 一种醋酸纤维素多孔微球的制备方法及其产品
CN103766351B (zh) * 2014-02-14 2015-11-04 国家纳米科学中心 一种纳米农药组合物及其制备方法
KR101558083B1 (ko) * 2014-04-07 2015-10-07 에스케이케미칼주식회사 약물함유 고분자미립구 제조방법
WO2016020901A1 (en) 2014-08-07 2016-02-11 Acerta Pharma B.V. Methods of treating cancers, immune and autoimmune diseases, and inflammatory diseases based on btk occupancy and btk resynthesis rate
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
IL316573A (en) 2017-03-26 2024-12-01 Mapi Pharma Ltd Storage systems containing glatiramer acetate for the treatment of multiple sclerosis
CN107412171B (zh) * 2017-04-21 2020-04-17 湖南赛隆药业有限公司 注射用左旋泮托拉唑钠长效微球冻干制剂及其制备方法
KR102142026B1 (ko) * 2017-05-31 2020-08-06 주식회사 대웅제약 방출제어가 용이한 서방성 약물 미립자의 제조방법
CN109316371B (zh) * 2018-09-21 2021-09-03 珀莱雅化妆品股份有限公司 一种芹菜素缓释制剂的制备方法
WO2020130585A1 (ko) * 2018-12-17 2020-06-25 주식회사 지투지바이오 데슬로렐린을 함유하는 서방형 주사제 및 그 제조방법
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DE102019126672B4 (de) * 2019-10-02 2021-07-01 Universität Rostock Wirkstoffdepotsystem sowie Kit zur in situ Polymerisation des Wirkstoffdepotsystems
CN111249524B (zh) * 2020-01-18 2020-12-08 南京医科大学附属口腔医院 用于骨组织再生的高孔隙率聚己内酯多孔微球支架及其制备方法
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CN115942935B (zh) * 2020-08-18 2025-09-05 奥克伍德实验室有限责任公司 包括氯胺酮的微球制剂及其制备和使用方法
US12685714B2 (en) 2020-08-18 2026-07-21 Oakwood Laboratories, Llc Microsphere formulations comprising ketamine and methods for making and using the same
JP7522402B2 (ja) * 2021-02-26 2024-07-25 熊本県 塩化ビニル系ポリマー粒子の製造方法
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Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT74025B (de) * 1914-10-16 1917-11-26 Siemens Ag Verfahren und Herstellung einer Mauer im Erdreich.
US4495509A (en) * 1983-06-09 1985-01-22 Moore Business Forms, Inc. Microencapsulation by interchange of multiple emulsions
AR240875A1 (es) * 1984-01-09 1991-03-27 Stauffer Chemical Co Procedimiento para producir capsulas de poliurea de dimensiones multiples que contienen un material inmiscible en agua en su interior y las capsulas resultantes
ATE61935T1 (de) * 1985-02-07 1991-04-15 Takeda Chemical Industries Ltd Verfahren zur herstellung von mikrokapseln.
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
JPH04247230A (ja) * 1991-02-01 1992-09-03 Fuji Photo Film Co Ltd マイクロカプセルの製造方法およびそれを用いた感光材料
FR2679788B1 (fr) * 1991-08-02 1994-03-18 Thorel Jean Noel Structures d'emulsions polyphasiques autostabilisees.
FR2702391B1 (fr) * 1993-03-11 1995-04-28 Roussel Uclaf Nouvelles émulsions multiples, leur préparation, leur application à la préparation de compositions cosmétiques et ces compositions cosmétiques.
JP3790567B2 (ja) * 1994-09-30 2006-06-28 武田薬品工業株式会社 徐放剤
DE19545257A1 (de) * 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
FR2742354B1 (fr) * 1995-12-15 1998-01-23 Oreal Emulsion e/h/e stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau
DE19719297A1 (de) * 1997-05-07 1998-11-12 Henkel Kgaa Verfahren zur Herstellung multipler W/O/W-Emulsionen
US6287587B2 (en) * 1997-07-15 2001-09-11 Takeda Chemical Industries, Ltd. Process for producing sustained-release preparation by in-water drying
FR2766737B1 (fr) * 1997-07-31 1999-09-24 Centre Nat Rech Scient Emulsions multiples et leurs applications

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CA2317769A1 (en) 2001-12-28
GB2363986A (en) 2002-01-16
ES2185460B1 (es) 2004-06-16
ITTO20000963A0 (it) 2000-10-13
ES2185460A1 (es) 2003-04-16
KR100392501B1 (ko) 2003-07-22
MXPA00009408A (es) 2002-03-15
BRPI0005287B1 (pt) 2019-01-22
FR2810885A1 (fr) 2002-01-04
CN1330921A (zh) 2002-01-16
KR20020000698A (ko) 2002-01-05
FR2810885B1 (fr) 2003-10-17
GB2363986B (en) 2002-12-11
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BR0005287A (pt) 2002-02-13
JP3641418B2 (ja) 2005-04-20
US6506410B1 (en) 2003-01-14
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PL348343A1 (en) 2002-01-02
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DE10045374A1 (de) 2002-01-24
ITTO20000963A1 (it) 2002-04-13
CA2317769C (en) 2005-03-15

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