IT1320273B1 - Microparticella a rilascio prolungato e metodo per la sua preparazione - Google Patents

Microparticella a rilascio prolungato e metodo per la sua preparazione

Info

Publication number
IT1320273B1
IT1320273B1 IT2000TO000963A ITTO20000963A IT1320273B1 IT 1320273 B1 IT1320273 B1 IT 1320273B1 IT 2000TO000963 A IT2000TO000963 A IT 2000TO000963A IT TO20000963 A ITTO20000963 A IT TO20000963A IT 1320273 B1 IT1320273 B1 IT 1320273B1
Authority
IT
Italy
Prior art keywords
preparation
prolonged release
release microparticle
microparticle
prolonged
Prior art date
Application number
IT2000TO000963A
Other languages
English (en)
Italian (it)
Inventor
Jin Kyu Park
Mork Soon Park
Dong Seon Kim
Il Ho Lim
Ung Kil Jee
Pyung Keun Myung
Sang Beom Kim
Goo Young Jung
Original Assignee
Dong Kook Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Kook Pharm Co Ltd filed Critical Dong Kook Pharm Co Ltd
Publication of ITTO20000963A0 publication Critical patent/ITTO20000963A0/it
Publication of ITTO20000963A1 publication Critical patent/ITTO20000963A1/it
Application granted granted Critical
Publication of IT1320273B1 publication Critical patent/IT1320273B1/it

Links

Classifications

    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00Heating by electric, magnetic or electromagnetic fields
    • H05B6/64Heating using microwaves
    • H05B6/80Apparatus for specific applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02BCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B40/00Technologies aiming at improving the efficiency of home appliances, e.g. induction cooking or efficient technologies for refrigerators, freezers or dish washers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glanulating (AREA)
IT2000TO000963A 2000-06-28 2000-10-13 Microparticella a rilascio prolungato e metodo per la sua preparazione IT1320273B1 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20000036178A KR100392501B1 (ko) 2000-06-28 2000-06-28 다중 에멀젼법에 의한 서방출성 미립구의 제조방법

Publications (3)

Publication Number Publication Date
ITTO20000963A0 ITTO20000963A0 (it) 2000-10-13
ITTO20000963A1 ITTO20000963A1 (it) 2002-04-13
IT1320273B1 true IT1320273B1 (it) 2003-11-26

Family

ID=19674602

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000TO000963A IT1320273B1 (it) 2000-06-28 2000-10-13 Microparticella a rilascio prolungato e metodo per la sua preparazione

Country Status (16)

Country Link
US (1) US6506410B1 (enExample)
JP (1) JP3641418B2 (enExample)
KR (1) KR100392501B1 (enExample)
CN (1) CN1330921A (enExample)
BR (2) BRPI0005287B1 (enExample)
CA (1) CA2317769C (enExample)
DE (1) DE10045374B4 (enExample)
ES (1) ES2185460B1 (enExample)
FR (1) FR2810885B1 (enExample)
GB (1) GB2363986B (enExample)
IN (1) IN189017B (enExample)
IT (1) IT1320273B1 (enExample)
MX (1) MXPA00009408A (enExample)
PL (1) PL348343A1 (enExample)
TR (1) TR200003123A2 (enExample)
ZA (1) ZA200004485B (enExample)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376242B1 (en) * 1999-09-21 2002-04-23 Emory University Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
WO2002043580A2 (en) 2000-10-27 2002-06-06 Epic Therapeutics, Inc. Production of microspheres
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
PT1418890E (pt) * 2001-08-16 2008-06-09 Baxter Int Formulações de micropartículas à base de propulsor
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
GB0129489D0 (en) * 2001-12-10 2002-01-30 Quadrant Healthcare Uk Ltd Sustained-release compositions
CA2471521C (en) * 2001-12-26 2010-11-02 Takeda Chemical Industries, Ltd. Novel microsphere and method for production thereof
EP1543722B1 (en) 2002-08-19 2015-04-15 Nagoya Industrial Science Research Institute Nonhuman animal reproducing pathogenic conditions of spinal and bulbar muscular atrophy and remedy for spinal and bulbar muscular atrophy
WO2004058844A1 (ja) * 2002-12-25 2004-07-15 E-Tec Co., Ltd. 樹脂微粒子及び樹脂マイクロカプセル、並びにそれらの製造方法
DE10315640A1 (de) * 2003-04-04 2004-10-14 Ignatov, Konstantin Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
US20040210118A1 (en) * 2003-04-18 2004-10-21 Michel Letort In situ detection of endoleak and endotension
US20040213767A1 (en) * 2003-04-23 2004-10-28 Marc Hendriks Methods for using adipose-derived cells for healing of aortic aneurysmal tissue
US20040215318A1 (en) * 2003-04-24 2004-10-28 Brian Kwitkin Timed delivery of therapeutics to blood vessels
US7387645B2 (en) * 2003-04-25 2008-06-17 Medtronic Vascular, Inc. Cellular therapy to heal vascular tissue
US20040254629A1 (en) * 2003-04-25 2004-12-16 Brian Fernandes Methods and apparatus for treatment of aneurysmal tissue
US7396540B2 (en) * 2003-04-25 2008-07-08 Medtronic Vascular, Inc. In situ blood vessel and aneurysm treatment
US20040215335A1 (en) * 2003-04-25 2004-10-28 Brin David S. Methods and apparatus for treatment of aneurysmal tissue
US20040215320A1 (en) * 2003-04-25 2004-10-28 James Machek Integral stent graft
ATE474606T1 (de) * 2003-05-23 2010-08-15 Gambro Lundia Ab Biokompatibles polymer
SE526027C2 (sv) 2003-05-23 2005-06-14 Gambro Lundia Ab Biokompatibel polymerkomposition, förfarande för beredning av en biokompatibel sampolymerkomposition, artikel med en film av en polymerkomposition och användning av en biokompatibel polymerkomposition för en medicinsk anordning
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
KR101137785B1 (ko) * 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
WO2005009375A2 (en) * 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20050043786A1 (en) * 2003-08-18 2005-02-24 Medtronic Ave, Inc. Methods and apparatus for treatment of aneurysmal tissue
US7371228B2 (en) * 2003-09-19 2008-05-13 Medtronic Vascular, Inc. Delivery of therapeutics to treat aneurysms
CN1314453C (zh) * 2003-09-25 2007-05-09 中国科学院过程工程研究所 尺寸均一、储存稳定的亲水性药物的复乳载体及其制备方法
TW200529890A (en) * 2004-02-10 2005-09-16 Takeda Pharmaceutical Sustained-release preparations
DK1765294T3 (da) * 2004-05-12 2008-11-10 Baxter Int Nukleinsyremikrokugler samt deres fremstilling og afgivelse
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
EP1758558B1 (en) * 2004-05-12 2013-10-16 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
MXPA06012992A (es) 2004-05-12 2007-02-12 Baxter Int Microesferas que comprenden proteina y que muestran inyectabilidad en altas concentraciones de este agente.
US20050266043A1 (en) * 2004-05-27 2005-12-01 Medtronic Vascular, Inc. Methods and compounds for treatment of aneurysmal tissue
US20050266042A1 (en) * 2004-05-27 2005-12-01 Medtronic Vascular, Inc. Methods and apparatus for treatment of aneurysmal tissue
US8048409B2 (en) * 2004-05-27 2011-11-01 Medtronic Vascular, Inc. Cellular therapy to heal vascular tissue
EP2594259A1 (en) * 2004-08-04 2013-05-22 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
WO2006036964A2 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Barrier layer
AU2006241145B2 (en) * 2005-04-27 2011-04-28 Baxter Healthcare S. A. Surface-modified microparticles and methods of forming and using the same
EP1933764A2 (en) * 2005-09-02 2008-06-25 Medtronic Vascular, Inc. Methods and apparatus for treatment of aneurysms adjacent to branch arteries
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
CN1939316B (zh) * 2005-09-28 2012-01-25 中国人民解放军军事医学科学院毒物药物研究所 含阿霉素的微球及其制备方法
US20080286375A1 (en) * 2005-11-15 2008-11-20 Amorepacific Corporation Method for Preparing Sustained-Release Microparticles Comprising Sucrose Acetate Isobutyrate
EP1968549B1 (en) * 2005-12-22 2014-05-14 Novartis AG Sustained release formulation comprising octreotide and two or more polylactide-co-glycolide polymers
KR100722607B1 (ko) * 2006-05-11 2007-05-28 주식회사 펩트론 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
KR100801194B1 (ko) * 2006-07-14 2008-02-11 한국과학기술원 세포 배양 및 전달용 다공성 생분해성 고분자 미립 담체와그의 제조방법
EP2056883B1 (en) * 2006-08-04 2021-09-22 Baxter International Inc. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
CN101511347B (zh) * 2006-08-31 2012-11-28 Sk化学株式会社 含药物微球的制造方法及由该方法制造的含药物微球
JP2010505882A (ja) * 2006-10-06 2010-02-25 バクスター・インターナショナル・インコーポレイテッド 表面改質微粒子を含むマイクロエンカプセルならびに、その形成および使用の方法
KR100845009B1 (ko) * 2007-08-07 2008-07-08 한국생명공학연구원 전하를 띠는 물질이 고착된 다공성 고분자 입자 및 그제조방법
WO2009067462A1 (en) * 2007-11-19 2009-05-28 Capsulated Systems Inc. Prolonged release of local anesthetics using microparticles and surgery applications
US8728528B2 (en) 2007-12-20 2014-05-20 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
KR101005562B1 (ko) 2008-05-01 2011-01-05 한국생명공학연구원 난용성 약물을 함유하는 균일한 크기의 고분자 나노입자제조방법
US8697098B2 (en) * 2011-02-25 2014-04-15 South Dakota State University Polymer conjugated protein micelles
GB2460915B (en) * 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
KR100963435B1 (ko) 2008-06-19 2010-06-17 한국과학기술연구원 서방형 약물전달 및 조직재생용 덮인 다공성 생분해성고분자 미립구의 제조 방법
US8034382B2 (en) * 2008-07-31 2011-10-11 The Board Of Trustees Of The University Of Arkansas Preparation method for biodegradable micro-particles containing drugs
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8323685B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US20100131051A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Systems and Methods for Treatment of Aneurysms Using Zinc Chelator(s)
US20100131001A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Targeted Drug Delivery for Aneurysm Treatment
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
US20100189800A1 (en) * 2009-01-23 2010-07-29 Peter Markland Continous double emulsion process for making microparticles
KR101663561B1 (ko) * 2009-02-18 2016-10-10 동국제약 주식회사 서방출성 미립구의 제조방법
CN101530396A (zh) * 2009-04-15 2009-09-16 西安力邦医药科技有限责任公司 氨氯地平微球的制备方法
KR101105292B1 (ko) 2009-06-05 2012-01-17 주식회사 리젠 바이오텍 생분해성 고분자 미세입자와 그의 제조방법
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
RU2545865C2 (ru) * 2009-09-22 2015-04-10 Евоник Корпорейшн Имплантируемые устройства с различными вариантами загрузки биологически активного компонента
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
WO2012009707A2 (en) 2010-07-16 2012-01-19 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
KR20120048811A (ko) * 2010-11-08 2012-05-16 에스케이케미칼주식회사 아나스트로졸 함유 고분자 미립구를 유효성분으로 포함하는 약학적 조성물
KR101785515B1 (ko) * 2010-11-08 2017-10-16 에스케이케미칼주식회사 올란자핀 함유 고분자 미립구를 유효성분으로 포함하는 약학적 조성물
KR101411349B1 (ko) * 2010-12-24 2014-06-25 주식회사 삼양바이오팜 생리활성 펩타이드를 포함하는 마이크로입자 및 그의 제조방법, 및 그를 포함하는 약제학적 조성물
KR101952599B1 (ko) 2011-02-25 2019-05-22 사우스다코타주립대학 고분자 컨쥬게이트화된 단백질 마이셀
KR101481859B1 (ko) * 2011-05-20 2015-01-14 에스케이케미칼주식회사 초기 약물 방출이 감소된 고분자 미립자의 제조방법 및 그 방법에 의해 제조된 고분자 미립자
CN102389756B (zh) * 2011-08-11 2014-01-01 长春金赛药业有限责任公司 复乳法制备微球的方法
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
CN105246500A (zh) 2013-04-05 2016-01-13 克劳迪娅·齐尔贝尔博格 基质金属蛋白酶及其用途
CN103211773B (zh) * 2013-04-10 2014-11-05 上海丽珠制药有限公司 一种制备醋酸亮丙瑞林微球的方法
KR101543507B1 (ko) * 2013-05-15 2015-08-11 씨제이헬스케어 주식회사 연속 공정의 미립구의 제조 방법 및 이로부터 제조된 미립구
CN103724635B (zh) * 2013-12-06 2016-01-20 中国烟草总公司郑州烟草研究院 一种醋酸纤维素多孔微球的制备方法及其产品
CN103766351B (zh) * 2014-02-14 2015-11-04 国家纳米科学中心 一种纳米农药组合物及其制备方法
KR101558083B1 (ko) * 2014-04-07 2015-10-07 에스케이케미칼주식회사 약물함유 고분자미립구 제조방법
TW201618783A (zh) 2014-08-07 2016-06-01 艾森塔製藥公司 以布魯頓(Bruton)氏酪胺酸激酶(BTK)佔據和BTK再合成速率為基礎之治療癌症、免疫和自體免疫疾病及發炎性疾病之方法
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HRP20250396T1 (hr) 2016-08-31 2025-05-23 Mapi Pharma Ltd. Depo sustavi koji sadrže glatiramer acetat
AU2018242998B2 (en) 2017-03-26 2023-11-02 Mapi Pharma Ltd. Glatiramer depot systems for treating progressive forms of multiple sclerosis
CN107412171B (zh) * 2017-04-21 2020-04-17 湖南赛隆药业有限公司 注射用左旋泮托拉唑钠长效微球冻干制剂及其制备方法
KR102142026B1 (ko) * 2017-05-31 2020-08-06 주식회사 대웅제약 방출제어가 용이한 서방성 약물 미립자의 제조방법
CN109316371B (zh) * 2018-09-21 2021-09-03 珀莱雅化妆品股份有限公司 一种芹菜素缓释制剂的制备方法
KR102185348B1 (ko) * 2018-12-17 2020-12-01 주식회사 지투지바이오 데슬로렐린을 함유하는 서방형 주사제 및 그 제조방법
CN110403736A (zh) * 2019-08-09 2019-11-05 常州市第二人民医院 一种3d打印超多孔钛合金促成骨表面改性方法
DE102019126672B4 (de) * 2019-10-02 2021-07-01 Universität Rostock Wirkstoffdepotsystem sowie Kit zur in situ Polymerisation des Wirkstoffdepotsystems
CN111249524B (zh) * 2020-01-18 2020-12-08 南京医科大学附属口腔医院 用于骨组织再生的高孔隙率聚己内酯多孔微球支架及其制备方法
CN111658620B (zh) * 2020-04-30 2022-04-19 天津医科大学口腔医院 一种透明质酸-帕瑞昔布plga微球及其制备方法和应用
JP2023538901A (ja) * 2020-08-18 2023-09-12 オークウッド ラボラトリーズ,エル.エル.シー. ケタミンを含むマイクロスフェア製剤ならびにその製造及び使用方法
JP7522402B2 (ja) * 2021-02-26 2024-07-25 熊本県 塩化ビニル系ポリマー粒子の製造方法
CN113648283B (zh) * 2021-07-23 2023-11-07 丽水市中心医院 靶向抑制HIF-2α的载药微球制备方法、载药微球及应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT74025B (de) * 1914-10-16 1917-11-26 Siemens Ag Verfahren und Herstellung einer Mauer im Erdreich.
US4495509A (en) * 1983-06-09 1985-01-22 Moore Business Forms, Inc. Microencapsulation by interchange of multiple emulsions
AR240875A1 (es) * 1984-01-09 1991-03-27 Stauffer Chemical Co Procedimiento para producir capsulas de poliurea de dimensiones multiples que contienen un material inmiscible en agua en su interior y las capsulas resultantes
EP0190833B1 (en) * 1985-02-07 1991-03-27 Takeda Chemical Industries, Ltd. Method for producing microcapsule
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
JPH04247230A (ja) * 1991-02-01 1992-09-03 Fuji Photo Film Co Ltd マイクロカプセルの製造方法およびそれを用いた感光材料
FR2679788B1 (fr) * 1991-08-02 1994-03-18 Thorel Jean Noel Structures d'emulsions polyphasiques autostabilisees.
FR2702391B1 (fr) * 1993-03-11 1995-04-28 Roussel Uclaf Nouvelles émulsions multiples, leur préparation, leur application à la préparation de compositions cosmétiques et ces compositions cosmétiques.
JP3790567B2 (ja) * 1994-09-30 2006-06-28 武田薬品工業株式会社 徐放剤
DE19545257A1 (de) * 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
FR2742354B1 (fr) * 1995-12-15 1998-01-23 Oreal Emulsion e/h/e stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau
DE19719297A1 (de) * 1997-05-07 1998-11-12 Henkel Kgaa Verfahren zur Herstellung multipler W/O/W-Emulsionen
US6287587B2 (en) * 1997-07-15 2001-09-11 Takeda Chemical Industries, Ltd. Process for producing sustained-release preparation by in-water drying
FR2766737B1 (fr) * 1997-07-31 1999-09-24 Centre Nat Rech Scient Emulsions multiples et leurs applications

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CN1330921A (zh) 2002-01-16
DE10045374A1 (de) 2002-01-24
KR100392501B1 (ko) 2003-07-22
DE10045374B4 (de) 2007-08-30
ZA200004485B (en) 2001-02-28
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CA2317769C (en) 2005-03-15
ITTO20000963A1 (it) 2002-04-13
TR200003123A2 (tr) 2002-01-21
FR2810885A1 (fr) 2002-01-04
BR0005287A (pt) 2002-02-13
BRPI0005287B1 (pt) 2019-01-22
ES2185460B1 (es) 2004-06-16
GB2363986A (en) 2002-01-16
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