YU47948B - Postupak za hlorovanje 6-estara sahoreze - Google Patents

Postupak za hlorovanje 6-estara sahoreze

Info

Publication number
YU47948B
YU47948B YU141190A YU141190A YU47948B YU 47948 B YU47948 B YU 47948B YU 141190 A YU141190 A YU 141190A YU 141190 A YU141190 A YU 141190A YU 47948 B YU47948 B YU 47948B
Authority
YU
Yugoslavia
Prior art keywords
sucrose
ester
mixture
produce
trichloro
Prior art date
Application number
YU141190A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU141190A (sh
Inventor
R.E. Walkup
J.L. Navia
N.M. Vernon
Original Assignee
Noramko Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23507711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU47948(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noramko Inc. filed Critical Noramko Inc.
Publication of YU141190A publication Critical patent/YU141190A/sh
Publication of YU47948B publication Critical patent/YU47948B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
YU141190A 1989-07-18 1990-07-18 Postupak za hlorovanje 6-estara sahoreze YU47948B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,147 US4980463A (en) 1989-07-18 1989-07-18 Sucrose-6-ester chlorination

Publications (2)

Publication Number Publication Date
YU141190A YU141190A (sh) 1992-07-20
YU47948B true YU47948B (sh) 1996-07-24

Family

ID=23507711

Family Applications (1)

Application Number Title Priority Date Filing Date
YU141190A YU47948B (sh) 1989-07-18 1990-07-18 Postupak za hlorovanje 6-estara sahoreze

Country Status (26)

Country Link
US (1) US4980463A (enExample)
EP (1) EP0409549B1 (enExample)
JP (1) JP3183506B2 (enExample)
KR (1) KR0144344B1 (enExample)
AR (1) AR247401A1 (enExample)
AT (1) ATE133175T1 (enExample)
AU (1) AU625908B2 (enExample)
CA (1) CA2021632C (enExample)
DE (1) DE69024868T2 (enExample)
DK (1) DK0409549T3 (enExample)
ES (1) ES2088973T3 (enExample)
FI (1) FI95802C (enExample)
GR (1) GR1002037B (enExample)
IE (1) IE69961B1 (enExample)
IL (1) IL94994A (enExample)
MX (1) MX164442B (enExample)
NO (1) NO175532C (enExample)
NZ (1) NZ234468A (enExample)
PE (1) PE21591A1 (enExample)
PH (1) PH26799A (enExample)
PT (1) PT94719B (enExample)
RU (1) RU1836377C (enExample)
TR (1) TR28705A (enExample)
TW (1) TW219939B (enExample)
YU (1) YU47948B (enExample)
ZA (1) ZA905615B (enExample)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136031A (en) * 1990-07-09 1992-08-04 Tate & Lyle Public Limited Company Chlorination of sugars
US5470969A (en) * 1990-08-27 1995-11-28 Mcneil-Ppc, Inc. Catalyzed sucrose-6-ester process
GB9110931D0 (en) * 1991-05-21 1991-07-10 Tate & Lyle Plc Process for the preparation of sucrose 6-esters
US5298611A (en) * 1993-03-12 1994-03-29 Mcneil-Ppc, Inc. Sucralose pentaester production
WO1996001832A1 (en) 1994-07-11 1996-01-25 The United States Of America, Represented By The Secretary Of The Department Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US6608039B1 (en) 1994-07-11 2003-08-19 The United States Of America As Represented By The Secretary Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
ZA958724B (en) * 1994-10-17 1997-04-16 Mcnell Ppc Inc Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
KR100405203B1 (ko) * 1996-05-23 2004-02-14 비앤티엔지니어링(주) 암거배수로관
IL131394A0 (en) * 1997-02-13 2001-01-28 Mcneil Ppc Inc Chromatographic purification of chlorinated sucrose
EP1076661A1 (en) * 1998-05-15 2001-02-21 Rostislav G. Zhbankov Method of preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
DE19924770A1 (de) * 1999-05-29 2000-12-21 Buna Sow Leuna Olefinverb Gmbh Verfahren zur Herstellung von Polyetherpolyolen aus Polysacchariden und deren Verwendung für die Herstellung von PUR-Schäumen
US6500973B2 (en) 2000-06-02 2002-12-31 Eastman Chemical Company Extractive solution crystallization of chemical compounds
DE60133011T2 (de) * 2000-08-25 2009-03-19 Eastman Chemical Co., Kingsport Verfahren zur herstellung von disaccharid und trisaccharid c6-c12 fettsäure-estern mit hohem alpha gehalt und materialien davon
US6667397B2 (en) * 2000-08-25 2003-12-23 Eastman Chemical Company Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom
BR0115482B1 (pt) * 2000-11-17 2013-02-19 sacralose cristalina, seu processo de cristalizaÇço e seu produto.
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
US6890581B2 (en) * 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US20040086605A1 (en) * 2002-10-30 2004-05-06 Sox Thomas E. Composition for delivering a high intensity sweetener
US6943248B2 (en) * 2003-04-30 2005-09-13 Tate & Lyle Public Limited Company Crystalline form of sucralose, and method for producing it
CN1176094C (zh) * 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
WO2005087020A1 (en) * 2004-03-05 2005-09-22 Richmond Chemical Corporation High-intensity sweetener-polyol compositions
MXPA06010665A (es) * 2004-03-19 2007-03-28 Pharmed Medicare Pvt Ltd Un proceso mejorado para producir sacarosa clorada.
US20050214425A1 (en) * 2004-03-23 2005-09-29 Roma Vazirani Sugar substitute prepared with nutritive and high-intensity sweeteners
WO2006061856A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Improved process for purificaton of 6 acetyl 4,1’,6’ trichlorogalactosucrose and 4,1’,6’ trichlorogalactosucrose by chromatography on silanized silica gel
WO2006061854A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited CONTROL OF pH BY DIRECT ADDITION OF CARBONATES AND BICARBONATES DURING CONCENTRATION OF ORGANIC SOLVENT EXTRACTS OF 6- ACETYL- 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE AND 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE
WO2006061855A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture
CN101175762A (zh) * 2005-01-03 2008-05-07 法马德医疗保险私人有限公司 通过氯化试剂的共-加入进行蔗糖-6-酯的氯化
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
US20080163867A1 (en) * 2005-02-22 2008-07-10 Molecular Separation Process in Various Steps of Process for Production of Chlorinated Sugars, Their Precursors and Derivatives
US20060205936A1 (en) * 2005-03-14 2006-09-14 Sl Laboratories, Llc Chlorination of Sucrose-6-esters
US20060247180A1 (en) * 2005-04-29 2006-11-02 Bergey James L Purgative composition and uses thereof
AU2006277556A1 (en) * 2005-05-04 2007-02-15 V.B. Medicare Private Limited Generation of Phosphorus Oxychloride as by-product from Phosphorus Pentachloride and DMF and its use for chlorination reaction by converting into Vilsmeier-Haack reagent.
GB2442619B (en) * 2005-05-04 2010-05-26 Pharmed Medicare Pvt Ltd Chlorination of sucrose acylates using triphosgene
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
CN102124017A (zh) * 2005-06-01 2011-07-13 V.B.医疗保险私人有限公司 利用溶剂萃取法纯化氯化蔗糖衍生物的方法
US20100160625A1 (en) * 2005-09-22 2010-06-24 Rakesh Ratnam Novel Preparation of 6-O-Acyl Chlorosucrose from Anhydrous Cholorinated Reaction Mass
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
JP2009528342A (ja) * 2006-02-28 2009-08-06 ヴイ ビー メディケア プライヴェート リミテッド 塩化チオニルを使用する糖類を塩素化するための新規塩素化試薬及び新規方法
CN100418976C (zh) * 2006-04-03 2008-09-17 广州科宏食品添加物有限公司 一种三氯蔗糖的制备方法
CN100402541C (zh) * 2006-06-15 2008-07-16 浙江工业大学 一种三氯蔗糖-6-乙酯的合成方法
CN101092438A (zh) * 2006-06-22 2007-12-26 南京莱因医药科技有限公司 6－o－苯甲酰三氯半乳型蔗糖四乙酯的制备方法
BRPI0621844A2 (pt) * 2006-07-06 2013-03-19 Alembic Ltd processo aperfeiÇoado para a preparaÇço de sucralose de alta pureza
CN100420697C (zh) * 2006-08-30 2008-09-24 河北苏科瑞科技有限公司 一种制备蔗糖-6-有机酸酯的方法
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US8258291B2 (en) * 2006-10-25 2012-09-04 Mamtek International Limited Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
GB0702857D0 (en) * 2007-01-19 2007-03-28 Tate & Lyle Plc Improved sucralose production method
US20080227971A1 (en) * 2007-01-19 2008-09-18 Leinhos Duane A Deacylation of sucralose-6-acylates
CN101260127B (zh) * 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
US20080300392A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
US20080300401A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US7932380B2 (en) * 2008-03-06 2011-04-26 Wanhe International (Group) Co. Ltd. Process for the preparation of sucralose
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
JP2011517445A (ja) * 2008-03-20 2011-06-09 テート アンド ライル テクノロジー リミテッド 第三級アミド溶媒からの酸の除去
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
TW200946683A (en) * 2008-04-03 2009-11-16 Tate & Lyle Technology Ltd A process for the purification of aqueous feed streams containing sucralose extraction efficiency
US20090299055A1 (en) * 2008-04-03 2009-12-03 Tate & Lyle Technology Limited Purification of Sucralose Containing Feed Streams for Sucralose Crystallization
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
US7862744B2 (en) * 2008-07-23 2011-01-04 Mamtek International Limited Methods and systems for preparing materials for sucralose production
US20100022765A1 (en) * 2008-07-23 2010-01-28 David Losan Ho Methods for extracting and purifying sucralose intermediate
GB2468936B (en) 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) * 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
GB2471348B (en) * 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
PL2609120T3 (pl) * 2010-08-25 2016-03-31 Davuluri Ramamohan Rao Ulepszony sposób wytwarzania sugammadeksu
AU2011332011B2 (en) * 2010-11-23 2017-01-12 Lexington Pharmaceuticals Laboratories, Llc Low temperature chlorination of carbohydrates
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
JP5679447B2 (ja) * 2011-06-20 2015-03-04 第一工業製薬株式会社 ショ糖ベンゾエート組成物の製造方法
US8884004B2 (en) 2011-09-02 2014-11-11 Divi's Laboratories, Ltd. Process for the preparation of sucralose
ES2574261T3 (es) * 2011-10-14 2016-06-16 Lexington Pharmaceuticals Laboratories, Llc Cloración de carbohidratos y derivados de carbohidratos
CN102964396B (zh) * 2012-10-26 2015-11-18 溧阳维信生物科技有限公司 一种三氯蔗糖-6-乙酯重结晶的方法
JP6109531B2 (ja) * 2012-11-02 2017-04-05 第一工業製薬株式会社 溶媒の除去方法
CN103145772A (zh) * 2013-03-26 2013-06-12 山东金城柯瑞化学有限公司 三氯蔗糖的制备方法
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
US10081651B2 (en) 2014-08-08 2018-09-25 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
CN104387427A (zh) * 2014-10-30 2015-03-04 安徽金禾实业股份有限公司 一种三氯蔗糖的生产方法
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN105131050B (zh) * 2015-07-22 2018-07-31 青岛科技大学 一种氯化剂的制备方法及其制备三氯蔗糖的方法
CN105859802B (zh) * 2016-05-14 2019-02-12 广西科技大学 一种三氯蔗糖的结晶和纯化方法
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
MX2023003704A (es) 2020-09-30 2023-05-09 Anhui Jinhe Ind Co Ltd Método de purificación de sucralosa.
CN113699196A (zh) * 2021-08-17 2021-11-26 安徽金禾实业股份有限公司 一种蔗糖-6-乙酸酯的无水酶法催化合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435440A (en) * 1976-01-08 1984-03-06 Tate & Lyle Limited Sweeteners
EP0010409A1 (en) * 1978-10-18 1980-04-30 TATE & LYLE PATENT HOLDINGS LIMITED Bittering agents
US4324888A (en) * 1979-03-09 1982-04-13 Talres Development (N.A.) N.V. Process for the preparation of chlorodeoxysugars
EP0031651B1 (en) * 1979-12-20 1983-03-23 TATE & LYLE PUBLIC LIMITED COMPANY Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
US4291158A (en) * 1980-01-28 1981-09-22 Velsicol Chemical Corporation Sucrose ester of 2-methoxy-3,6-dichlorobenzoic acid
US4345933A (en) * 1980-01-28 1982-08-24 Velsicol Chemical Corporation Sucrose ester of 2-methoxy-3,6-dichlorobenzoic acid
ATE9355T1 (de) * 1980-07-08 1984-09-15 Tate & Lyle Public Limited Company Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs).
IE55619B1 (en) * 1982-09-13 1990-11-21 Tate & Lyle Plc 6-derivatives of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
GB8316790D0 (en) * 1983-06-21 1983-07-27 Tate & Lyle Plc Chemical process
GB8622345D0 (en) * 1986-09-17 1986-10-22 Tate & Lyle Plc Sucrose derivatives

Also Published As

Publication number Publication date
AU5906990A (en) 1991-01-24
ES2088973T3 (es) 1996-10-01
AU625908B2 (en) 1992-07-16
KR0144344B1 (ko) 1998-07-01
JP3183506B2 (ja) 2001-07-09
GR900100537A (el) 1991-12-10
GR1002037B (en) 1995-10-31
FI95802B (fi) 1995-12-15
PE21591A1 (es) 1991-07-22
CA2021632A1 (en) 1991-01-19
EP0409549A3 (en) 1992-08-26
JPH03218388A (ja) 1991-09-25
TR28705A (tr) 1997-01-27
US4980463A (en) 1990-12-25
ATE133175T1 (de) 1996-02-15
KR910002885A (ko) 1991-02-26
AR247401A1 (es) 1994-12-29
DE69024868T2 (de) 1996-07-11
NO175532B (no) 1994-07-18
IE69961B1 (en) 1996-10-16
PH26799A (en) 1992-10-13
IL94994A0 (en) 1991-06-10
FI903603A0 (fi) 1990-07-17
NO903190L (no) 1991-01-21
PT94719B (pt) 1997-04-30
IL94994A (en) 1994-06-24
NO903190D0 (no) 1990-07-17
FI95802C (fi) 1996-03-25
EP0409549B1 (en) 1996-01-17
CA2021632C (en) 2000-09-12
PT94719A (pt) 1991-03-20
ZA905615B (en) 1992-03-25
EP0409549A2 (en) 1991-01-23
DE69024868D1 (de) 1996-02-29
IE902603A1 (en) 1991-02-27
DK0409549T3 (da) 1996-02-12
MX164442B (es) 1992-08-13
YU141190A (sh) 1992-07-20
NZ234468A (en) 1992-01-29
TW219939B (enExample) 1994-02-01
NO175532C (no) 1994-10-26
RU1836377C (ru) 1993-08-23

Similar Documents

Publication Publication Date Title
YU47948B (sh) Postupak za hlorovanje 6-estara sahoreze
DE69434532D1 (de) Verfahren zur Herstellung eines Produktes mit hohem Trehalosegehalt
AU7818691A (en) Method of producing eicosapentaenoic acid or the ester derivatives thereof
DE3687564D1 (de) Verfahren zur herstellung von 1,6-dichlor-1,6-dideoxy-beta-d-fructofuranosyl-4-chlor-4-deoxy-alpha-galactopyranosid.
GB2011900A (en) N'-substituted -aminoalkanoyl- -aminoalkanoic acids their use and process for their production as well as pharmaceutical products containing these compounds
FR2322189A1 (fr) Procede d'amelioration de la stabilite a l'hydrolyse de la liaison entre des surfaces d'acier et des produits adhesifs organiques
IT7825713A0 (it) Derivati d'acido ciclopropancarbossilico, processo per la loro produzione e loro impiego come prodotti per laproduzione d'insetticidi.
SE7706425L (sv) Forfarande for framstellning av polyribonukleotider med aktivitet vid alstrandet av leukocyter och blodplettar
ATE125731T1 (de) Verfahren zur modifizierung eines molekularsiebes.
KR880007434A (ko) 치환 아미노메틸-5,6,7,8-테트라히드로나프틸옥시아세트산, 신규 중간체 생성물, 그의 제조 방법 및 의약품에 있어서 그의 용도
JPS645460A (en) Production of delaying gelatinous material
ATE40353T1 (de) Verfahren zur herstellung von chlorierten pyridinderivaten und radikal initiatoren verwendet in diesem verfahren.
BE862417A (fr) Procede de preparation d'acide methacrylique et de derives fonctionnels de cet acide, et produits obtenus
FR2354774A1 (fr) Derives de l'acide adenosine-5'-monophosphorique et medicament contenant ces substances
ATE42203T1 (de) Semi-synthetisches verfahren zur herstellung von insulin.
FR2702482B1 (fr) Nouveau procede de preparation d'alkylpolyosides faiblement colores et a faible teneur en produits de degradation acide.
CS274696B2 (en) Method of 4-chloro-3-alkoxybut-2e-enoic acid's alkyl esters production
FR2547812B1 (fr) Procede d'halogenation et de fluoration simultanees de derives aromatiques
ATE15044T1 (de) Bis-ester von alkandiolen, pharmazeutische zusammensetzungen und zwischenprodukte.
ZA919958B (en) Method for the preparation of substituted and unsubstituted 2,3-pyridine and quinolinedicarboxylic acids
GR1000429B (el) Συνθεση με βαση την τριμεβουτινη παρατεταμενης απελευθερωσης και μεθοδος παρασκευης της.
GR3019276T3 (en) Process for making 2-oxindole-1-carboxamides
ATE46165T1 (de) Verfahren zur herstellung von 7oxabicyclo(2,2,1)hept-5-en-derivaten.
ATE132147T1 (de) Verfahren zur herstellung von 2,2-difluoro-1,3- benzodioxole
DE69212072D1 (de) Kontinuierliches Verfahren zur Herstellung von Sucrose-6-Estern