ATE24317T1 - 4-methyl-6-phenyl-pyridazinderivate mit einer wirkung auf das zentrale nervensystem. - Google Patents

4-methyl-6-phenyl-pyridazinderivate mit einer wirkung auf das zentrale nervensystem.

Info

Publication number
ATE24317T1
ATE24317T1 AT82401423T AT82401423T ATE24317T1 AT E24317 T1 ATE24317 T1 AT E24317T1 AT 82401423 T AT82401423 T AT 82401423T AT 82401423 T AT82401423 T AT 82401423T AT E24317 T1 ATE24317 T1 AT E24317T1
Authority
AT
Austria
Prior art keywords
methyl
phenyl
effect
nervous system
central nervous
Prior art date
Application number
AT82401423T
Other languages
English (en)
Inventor
Camille Wermuth
Horace Davi
Katleen Biziere
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE24317T1 publication Critical patent/ATE24317T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT82401423T 1981-08-10 1982-07-30 4-methyl-6-phenyl-pyridazinderivate mit einer wirkung auf das zentrale nervensystem. ATE24317T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8115435A FR2510997A1 (fr) 1981-08-10 1981-08-10 Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
EP82401423A EP0072299B1 (de) 1981-08-10 1982-07-30 4-Methyl-6-Phenyl-Pyridazinderivate mit einer Wirkung auf das zentrale Nervensystem

Publications (1)

Publication Number Publication Date
ATE24317T1 true ATE24317T1 (de) 1987-01-15

Family

ID=9261319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82401423T ATE24317T1 (de) 1981-08-10 1982-07-30 4-methyl-6-phenyl-pyridazinderivate mit einer wirkung auf das zentrale nervensystem.

Country Status (29)

Country Link
US (3) US4576946A (de)
EP (1) EP0072299B1 (de)
JP (1) JPS5838262A (de)
KR (1) KR880002710B1 (de)
AT (1) ATE24317T1 (de)
AU (1) AU548029B2 (de)
CA (1) CA1180704A (de)
CS (1) CS241052B2 (de)
DD (3) DD209453A5 (de)
DE (1) DE3274737D1 (de)
DK (1) DK148654C (de)
EG (1) EG15922A (de)
ES (1) ES514854A0 (de)
FI (1) FI74462C (de)
FR (1) FR2510997A1 (de)
GR (1) GR76235B (de)
HU (1) HU190695B (de)
IE (1) IE53611B1 (de)
IL (1) IL66423A0 (de)
MA (1) MA19561A1 (de)
NO (1) NO157141C (de)
NZ (1) NZ201530A (de)
OA (1) OA07178A (de)
PH (1) PH17883A (de)
PL (3) PL137265B1 (de)
PT (1) PT75371B (de)
SU (2) SU1366056A3 (de)
YU (3) YU171782A (de)
ZA (1) ZA825516B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539741A1 (fr) * 1983-01-21 1984-07-27 Sanofi Sa Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action
FR2601011B1 (fr) * 1986-07-03 1988-10-28 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
JP3553142B2 (ja) * 1994-07-29 2004-08-11 花王株式会社 ４級アンモニウム塩の製造方法及び中間体ジアミノアルコール
AU2005260102A1 (en) * 2004-05-08 2006-01-12 Novartis International Pharmaceutical Ltd. 3-aryl-5,6-disubstituted pyridazines
EP1741709A1 (de) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl substituierte Amide mit gesättigtem Linker, und deren Verwendung als Pharmaka
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) * 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
WO2011133920A1 (en) 2010-04-23 2011-10-27 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
MA41598A (fr) * 2015-02-25 2018-01-02 Constellation Pharmaceuticals Inc Composés thérapeutiques de pyridazine et leurs utilisations
AR119731A1 (es) 2019-05-17 2022-01-05 Novartis Ag Inhibidores del inflamasoma nlrp3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2388799A1 (fr) * 1977-04-28 1978-11-24 Rolland Sa A Derives de pyridazinone, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
FR2510997A1 (fr) 1983-02-11
FI822767L (fi) 1983-02-11
NO157141C (no) 1988-01-27
YU209784A (en) 1985-04-30
DD213213A5 (de) 1984-09-05
EG15922A (en) 1986-06-30
ES8305735A1 (es) 1983-05-01
NZ201530A (en) 1985-05-31
KR840001146A (ko) 1984-03-28
DK357482A (da) 1983-02-11
PT75371B (en) 1984-12-10
DD209453A5 (de) 1984-05-09
CS241052B2 (en) 1986-03-13
IE53611B1 (en) 1988-12-21
JPS5838262A (ja) 1983-03-05
PL237837A1 (en) 1984-05-07
OA07178A (fr) 1984-04-30
EP0072299A3 (en) 1984-01-11
PT75371A (en) 1982-09-01
US4677106A (en) 1987-06-30
GR76235B (de) 1984-08-04
MA19561A1 (fr) 1983-04-01
NO822705L (no) 1983-02-11
PL137265B1 (en) 1986-05-31
DK148654C (da) 1986-02-17
EP0072299B1 (de) 1986-12-17
PL137262B1 (en) 1986-05-31
DK148654B (da) 1985-08-26
PH17883A (en) 1985-01-21
FI74462B (fi) 1987-10-30
SU1356961A3 (ru) 1987-11-30
NO157141B (no) 1987-10-19
FR2510997B1 (de) 1984-02-10
ZA825516B (en) 1983-06-29
HU190695B (en) 1986-10-28
FI822767A0 (fi) 1982-08-09
CS591282A2 (en) 1985-06-13
YU171782A (en) 1985-04-30
DD213212A5 (de) 1984-09-05
IL66423A0 (en) 1982-11-30
SU1366056A3 (ru) 1988-01-07
IE821821L (en) 1983-02-10
JPH0417950B2 (de) 1992-03-26
EP0072299A2 (de) 1983-02-16
FI74462C (fi) 1988-02-08
DE3274737D1 (en) 1987-01-29
CA1180704A (en) 1985-01-08
ES514854A0 (es) 1983-05-01
KR880002710B1 (ko) 1988-12-26
PL243376A1 (en) 1984-04-24
PL243377A1 (en) 1984-04-24
AU8661982A (en) 1983-02-17
YU209684A (en) 1985-04-30
US4514397A (en) 1985-04-30
AU548029B2 (en) 1985-11-21
PL137201B1 (en) 1986-05-31
US4576946A (en) 1986-03-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee