DK0409549T3 - Forbedret saccharose-6-esterchlorering - Google Patents

Forbedret saccharose-6-esterchlorering

Info

Publication number
DK0409549T3
DK0409549T3 DK90307784.0T DK90307784T DK0409549T3 DK 0409549 T3 DK0409549 T3 DK 0409549T3 DK 90307784 T DK90307784 T DK 90307784T DK 0409549 T3 DK0409549 T3 DK 0409549T3
Authority
DK
Denmark
Prior art keywords
improved sucrose
ester chlorination
chlorination
ester
sucrose
Prior art date
Application number
DK90307784.0T
Other languages
English (en)
Inventor
Robert E Walkup
Juan L Navia
Nicholas M Vernon
Original Assignee
Noramco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23507711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0409549(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noramco Inc filed Critical Noramco Inc
Application granted granted Critical
Publication of DK0409549T3 publication Critical patent/DK0409549T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
DK90307784.0T 1989-07-18 1990-07-17 Forbedret saccharose-6-esterchlorering DK0409549T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,147 US4980463A (en) 1989-07-18 1989-07-18 Sucrose-6-ester chlorination

Publications (1)

Publication Number Publication Date
DK0409549T3 true DK0409549T3 (da) 1996-02-12

Family

ID=23507711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90307784.0T DK0409549T3 (da) 1989-07-18 1990-07-17 Forbedret saccharose-6-esterchlorering

Country Status (26)

Country Link
US (1) US4980463A (da)
EP (1) EP0409549B1 (da)
JP (1) JP3183506B2 (da)
KR (1) KR0144344B1 (da)
AR (1) AR247401A1 (da)
AT (1) ATE133175T1 (da)
AU (1) AU625908B2 (da)
CA (1) CA2021632C (da)
DE (1) DE69024868T2 (da)
DK (1) DK0409549T3 (da)
ES (1) ES2088973T3 (da)
FI (1) FI95802C (da)
GR (1) GR1002037B (da)
IE (1) IE69961B1 (da)
IL (1) IL94994A (da)
MX (1) MX164442B (da)
NO (1) NO175532C (da)
NZ (1) NZ234468A (da)
PE (1) PE21591A1 (da)
PH (1) PH26799A (da)
PT (1) PT94719B (da)
RU (1) RU1836377C (da)
TR (1) TR28705A (da)
TW (1) TW219939B (da)
YU (1) YU47948B (da)
ZA (1) ZA905615B (da)

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WO1996001832A1 (en) 1994-07-11 1996-01-25 The United States Of America, Represented By The Secretary Of The Department Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US6608039B1 (en) 1994-07-11 2003-08-19 The United States Of America As Represented By The Secretary Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US5498709A (en) 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
KR100405203B1 (ko) * 1996-05-23 2004-02-14 비앤티엔지니어링(주) 암거배수로관
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RU2217435C2 (ru) * 1998-05-15 2003-11-27 Ростислав Георгиевич Жбанков Способ получения 4,1'6'-трихлор-4,1',6'-тридезоксигалактосахарозы
DE19924770A1 (de) * 1999-05-29 2000-12-21 Buna Sow Leuna Olefinverb Gmbh Verfahren zur Herstellung von Polyetherpolyolen aus Polysacchariden und deren Verwendung für die Herstellung von PUR-Schäumen
US6500973B2 (en) 2000-06-02 2002-12-31 Eastman Chemical Company Extractive solution crystallization of chemical compounds
DE60133011T2 (de) * 2000-08-25 2009-03-19 Eastman Chemical Co., Kingsport Verfahren zur herstellung von disaccharid und trisaccharid c6-c12 fettsäure-estern mit hohem alpha gehalt und materialien davon
US6667397B2 (en) * 2000-08-25 2003-12-23 Eastman Chemical Company Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom
AU2002226918B2 (en) * 2000-11-17 2006-05-25 Tate & Lyle Technology Limited Improved sucralose composition and process for the crystallization thereof
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6890581B2 (en) * 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
US20040086605A1 (en) * 2002-10-30 2004-05-06 Sox Thomas E. Composition for delivering a high intensity sweetener
US6943248B2 (en) 2003-04-30 2005-09-13 Tate & Lyle Public Limited Company Crystalline form of sucralose, and method for producing it
CN1176094C (zh) * 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
US20050196503A1 (en) * 2004-03-05 2005-09-08 Sunil Srivastava High-intensity sweetener-polyol compositions
CA2560284A1 (en) * 2004-03-19 2005-09-29 Pharmed Medicare Pvt. Ltd. An improved process for producing chlorinated sucrose
US20050214425A1 (en) * 2004-03-23 2005-09-29 Roma Vazirani Sugar substitute prepared with nutritive and high-intensity sweeteners
WO2006061856A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Improved process for purificaton of 6 acetyl 4,1’,6’ trichlorogalactosucrose and 4,1’,6’ trichlorogalactosucrose by chromatography on silanized silica gel
CN101098971B (zh) * 2004-12-10 2010-04-21 V.B.医疗保险私人有限公司 有助于从含水反应混合物中选择性萃取4,1',6'三氯半乳蔗糖的盐
GB2437205B (en) * 2004-12-10 2010-03-17 Pharmed Medicare Pvt Ltd Control of ph by direct addition of carbonates and bicarbonates during concentration of organic solvent extracts of 6-acetyl-4,1',6'trichlorogalactosucrose
CN101175762A (zh) * 2005-01-03 2008-05-07 法马德医疗保险私人有限公司 通过氯化试剂的共-加入进行蔗糖-6-酯的氯化
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
CN101166748A (zh) * 2005-02-22 2008-04-23 法马德医疗保险私人有限公司 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法
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KR20080004575A (ko) * 2005-05-04 2008-01-09 팜드 메디케어 프리베이트 리미티드 염소화 반응을 위한 디(트리클로로메틸)카보네이트 유래의빌스마이어 헥크 시약의 합성
GB2441917A (en) * 2005-06-01 2008-03-19 Pharmed Medicare Pvt Ltd Method for purification of chlorinated sucrose derivatives by solvent extraction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
WO2007057920A2 (en) * 2005-09-22 2007-05-24 Pharmed Medicare Pvt. Ltd. Novel preparation of 6-o-acyl chlorosucrose from anhydrous chlorinated reaction mass
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
BRPI0707033A2 (pt) * 2006-02-28 2011-04-12 Vb Medicare Pvt Ltd reagente de cloração e processo para cloração de açúcares, por meio do uso de cloreto de tionila
CN100418976C (zh) * 2006-04-03 2008-09-17 广州科宏食品添加物有限公司 一种三氯蔗糖的制备方法
CN100402541C (zh) * 2006-06-15 2008-07-16 浙江工业大学 一种三氯蔗糖-6-乙酯的合成方法
CN101092438A (zh) * 2006-06-22 2007-12-26 南京莱因医药科技有限公司 6－o－苯甲酰三氯半乳型蔗糖四乙酯的制备方法
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CN100420697C (zh) * 2006-08-30 2008-09-24 河北苏科瑞科技有限公司 一种制备蔗糖-6-有机酸酯的方法
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US8258291B2 (en) * 2006-10-25 2012-09-04 Mamtek International Limited Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
US20080227971A1 (en) * 2007-01-19 2008-09-18 Leinhos Duane A Deacylation of sucralose-6-acylates
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US20080300401A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
US20080300392A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
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US7932380B2 (en) * 2008-03-06 2011-04-26 Wanhe International (Group) Co. Ltd. Process for the preparation of sucralose
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
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US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
CN101981044B (zh) * 2008-04-03 2014-08-06 塔特和莱利技术有限公司 碳水化合物浓度对三氯半乳蔗糖萃取效率的影响
WO2009124113A1 (en) * 2008-04-03 2009-10-08 Tate & Lyle Technology Ltd. Extraction of less polar impurities from sucralose containing aqueous feed streams
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
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US20100022765A1 (en) * 2008-07-23 2010-01-28 David Losan Ho Methods for extracting and purifying sucralose intermediate
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GB2468936B (en) * 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
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JP5679447B2 (ja) * 2011-06-20 2015-03-04 第一工業製薬株式会社 ショ糖ベンゾエート組成物の製造方法
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CN102964396B (zh) * 2012-10-26 2015-11-18 溧阳维信生物科技有限公司 一种三氯蔗糖-6-乙酯重结晶的方法
JP6109531B2 (ja) * 2012-11-02 2017-04-05 第一工業製薬株式会社 溶媒の除去方法
CN103145772A (zh) * 2013-03-26 2013-06-12 山东金城柯瑞化学有限公司 三氯蔗糖的制备方法
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CN106573949B (zh) * 2014-08-08 2019-03-15 塔特和莱利技术有限公司 蔗糖-6-酯的氯化
CN104387427A (zh) * 2014-10-30 2015-03-04 安徽金禾实业股份有限公司 一种三氯蔗糖的生产方法
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN105131050B (zh) * 2015-07-22 2018-07-31 青岛科技大学 一种氯化剂的制备方法及其制备三氯蔗糖的方法
CN105859802B (zh) * 2016-05-14 2019-02-12 广西科技大学 一种三氯蔗糖的结晶和纯化方法
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CN113699196A (zh) * 2021-08-17 2021-11-26 安徽金禾实业股份有限公司 一种蔗糖-6-乙酸酯的无水酶法催化合成方法

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ATE732T1 (de) * 1978-10-18 1982-03-15 Tate & Lyle Patent Holdings Limited Verfahren zur herstellung von 2-chlor-2-deoxy-sacchariden und einige 2-chlor-2-deoxy-saccharide.
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EP0043649B1 (en) * 1980-07-08 1984-09-12 TATE & LYLE PUBLIC LIMITED COMPANY Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
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Also Published As

Publication number Publication date
IE902603A1 (en) 1991-02-27
AU625908B2 (en) 1992-07-16
DE69024868T2 (de) 1996-07-11
GR1002037B (en) 1995-10-31
RU1836377C (ru) 1993-08-23
CA2021632C (en) 2000-09-12
JPH03218388A (ja) 1991-09-25
ES2088973T3 (es) 1996-10-01
IE69961B1 (en) 1996-10-16
DE69024868D1 (de) 1996-02-29
AR247401A1 (es) 1994-12-29
CA2021632A1 (en) 1991-01-19
PH26799A (en) 1992-10-13
FI95802B (fi) 1995-12-15
IL94994A0 (en) 1991-06-10
YU141190A (sh) 1992-07-20
JP3183506B2 (ja) 2001-07-09
EP0409549B1 (en) 1996-01-17
NO175532C (no) 1994-10-26
PT94719A (pt) 1991-03-20
ATE133175T1 (de) 1996-02-15
AU5906990A (en) 1991-01-24
KR910002885A (ko) 1991-02-26
TW219939B (da) 1994-02-01
TR28705A (tr) 1997-01-27
YU47948B (sh) 1996-07-24
IL94994A (en) 1994-06-24
ZA905615B (en) 1992-03-25
FI903603A0 (fi) 1990-07-17
FI95802C (fi) 1996-03-25
EP0409549A2 (en) 1991-01-23
NO903190D0 (no) 1990-07-17
US4980463A (en) 1990-12-25
KR0144344B1 (ko) 1998-07-01
MX164442B (es) 1992-08-13
PT94719B (pt) 1997-04-30
EP0409549A3 (en) 1992-08-26
NO175532B (no) 1994-07-18
GR900100537A (el) 1991-12-10
NO903190L (no) 1991-01-21
PE21591A1 (es) 1991-07-22
NZ234468A (en) 1992-01-29

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